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New insight into how protein E75 may control circadian rhythms and metabolic processes

University of Toronto researchers have gained new insight into how a specific protein may control circadian rhythms and metabolic processes, which has implications for treating cholesterol-related diseases.

28 Jul 2005

Anti-inflammatory function of Alzheimer's disease drugs revealed

The mechanism in anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been revealed by researchers at the Hebrew university of Jerusalem.

28 Jul 2005

Study raises concern about the use of beta blockers for all heart patients

Doubt has been cast on the popular practice of giving most heart patients drugs that reduce the heart's workload before and after major surgery, after new research has raised concerns about it.

28 Jul 2005

Scientists discover genes linked to spread of breast cancer

In new research scientists have identified genes which enable breast cancer cells to spread to the lungs, and the discovery could very well improve diagnosis and treatment of the disease.

28 Jul 2005

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Carbon monoxide, a poisonous gas that kills thousands of Americans every year, could turn out to be a life-saver for patients recovering from organ transplants, strokes or heart attacks, according to new research from the University of Michigan Cardiovascular Center.

28 Jul 2005

Bone marrow may be source of new egg-cell generation

Last year a group of Massachusetts General Hospital (MGH) researchers announced surprising findings that female mice - contrary to longstanding theories of mammalian reproductive physiology - retained the ability to make new egg cells or oocytes into adulthood.

27 Jul 2005

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Imagine a cancer drug that can burrow into a tumor, seal the exits and detonate a lethal dose of anti-cancer toxins, all while leaving healthy cells unscathed.

27 Jul 2005

Infectious diseases pose a serious threat to the nation's public health

Infectious diseases pose a serious threat to the nation's public health. Today, experts addressed key developments to the current and future outlook of infectious diseases, highlighting adolescent immunizations, outbreaks and epidemics of infectious diseases, antimicrobial resistance and new developments in HIV medicine, at a press conference sponsored by the National Foundation for Infectious Diseases (NFID).

27 Jul 2005

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Opiates appear to better "ameliorate the withdrawal, facilitate feeding and potentially reduce the likelihood of seizures," according to two new systematic reviews done by David Osborn, a neonatologist at the Royal Prince Alfred Hospital in Sydney, Australia, and colleagues.

26 Jul 2005

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

The effectiveness of chemotherapy in patients with advanced breast cancer can be evaluated earlier by using 18F-FDG positron emission tomography (PET) imaging over other conventional imaging procedures, according to an article in the July issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

26 Jul 2005

Single prenatal dose of methamphetamine enough to cause long-term neurodevelopmental problems in babies

In research published in the August issue of Free Radical Biology and Medicine, U of T pharmacy and pharmacology professor Peter Wells and his colleagues determined that exposing pregnant mice only once to methamphetamine led to delivery of offspring with long-term neurodevelopmental problems, including reduced motor co-ordination.

26 Jul 2005

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

The study found that almost three fourths of those 80 years and older have hypertension -- blood pressure greater than 140 systolic over greater than 90 diastolic. Fewer than 10 percent have "normal" blood pressure levels -- less than 120 systolic over less than 80 diastolic.

26 Jul 2005

GenoMed submits 50th provisional patent application

GenoMed announced today that the Company has submitted its 50th provisional patent application, a major milestone in any development stage company. GenoMed has so far been awarded two patents, one for treating acute kidney failure without dialysis, and another for hastening lung maturation in prematurely born infants.

26 Jul 2005

TEVA to acquire IVAX for $7.4 billion

TEVA Pharmaceutical Industries and IVAX Corporation have jointly announced that they have signed a definitive agreement providing for the acquisition of IVAX by TEVA.

26 Jul 2005

Acetaminophen, when taken as directed, is safe for patients with liver disease

Contrary to common perception, clinical data demonstrate that acetaminophen is an appropriate pain relief choice for patients with chronic liver disease. According to a systematic literature review of the data, which is published in the current issue of the American Journal of Therapeutics, there is no evidence that acetaminophen at therapeutic doses aggravates liver disease.

26 Jul 2005

Analysis of the Phase I/II clinical trial of HIV drug candidate PA-457

V.I. Technologies (Vitex) and collaborators at the University at Buffalo's School of Pharmacy and Pharmaceutical Sciences, Buffalo, NY, today presented a detailed analysis of the Phase I/II clinical trial of its HIV drug candidate PA-457 at the 3rd International AIDS Society (IAS) Conference on HIV Pathogenesis and Treatment in Rio de Janeiro, Brazil.

26 Jul 2005

Combination therapy based on artemisinins might not be the ideal treatment for malaria

If used alone, artemisinins will cure the most severe type of malaria - falciparum malaria - in seven days. However, when used on their own, they have a high risk of the malaria coming back and hence must be combined with other antimalarials to work best.

26 Jul 2005

Drugs News and Research

New insight into how protein E75 may control circadian rhythms and metabolic processes

Anti-inflammatory function of Alzheimer's disease drugs revealed

Study raises concern about the use of beta blockers for all heart patients

Scientists discover genes linked to spread of breast cancer

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Bone marrow may be source of new egg-cell generation

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Infectious diseases pose a serious threat to the nation's public health

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

Single prenatal dose of methamphetamine enough to cause long-term neurodevelopmental problems in babies

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

GenoMed submits 50th provisional patent application

TEVA to acquire IVAX for $7.4 billion

Acetaminophen, when taken as directed, is safe for patients with liver disease

Analysis of the Phase I/II clinical trial of HIV drug candidate PA-457

Combination therapy based on artemisinins might not be the ideal treatment for malaria

Multiple rare mutations within a single gene may increase risk for autism

Pneumonia - another use for statins

Nonsmokers report better health and fewer symptoms of depression than smokers

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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