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Thrombospondin (TSP-1) can cause kidney failure when normal blood flow is disrupted

Scientists led by a University of Cincinnati (UC) kidney expert have found that a naturally occurring protein that normally fights cancer cells can also cause severe kidney failure when normal blood flow is disrupted.

26 Nov 2005

United Kingdom has among the highest reported rates of primary resistance to HIV drugs worldwide

Those infected with HIV in the UK have one of the highest rates of resistance to anti-HIV drugs of anywhere in the world, prompting fears of a second wave epidemic of resistant virus, a new study claims in the British Medical Journal (BMJ).

26 Nov 2005

Tuberculosis research

It is estimated that two billion people--or one-third of the world's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths.

26 Nov 2005

Researchers identify genes affected by Methotrexate (MTX)

A Queen's University study of fruit flies that may revolutionize the way birth defects are studied has identified the genes affected by a widely-prescribed drug known to cause birth defects.

26 Nov 2005

High blood pressure research advances efforts to tailor drugs to individual patients

Having high blood pressure and a particular genetic alteration dramatically increases the risk of heart attack, stroke or death, and may explain why some hypertensive patients fare worse than others - even if they take the same medication, University of Florida researchers announced.

26 Nov 2005

Fear gene discovered

In the Nov. 18 issue of Cell, researchers report the discovery of a gene that controls the ability to react with appropriate fear to impending danger.

26 Nov 2005

Study of two drugs for angina treatment shows equal outcomes to patients

Researchers have found that the blood-thinning drug Lovenox works as well as a standard artery-clearing drug in patients with severe heart-related chest pain, but neither reduced the risk of death after a year of treatment.

24 Nov 2005

Personal computers will help fight AIDS

A new project, called FightAIDS@Home, is hoping to tap into the unused power of individual and business computers to help research and identify drugs used to combat the HIV virus.

24 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Aspirin can significantly reduce the risk of stroke in women

A meta-analysis of more than 95,000 patients has shown that aspirin can significantly reduce the risk of stroke in women, but it appears to have no protective effect in men, according to a new analysis by Duke University Medical Center cardiologists.

21 Nov 2005

Heart patients, do you tell your doctor you're using alternative medicines?

Doctors, do you ask your patients if they're using alternative medicines?

21 Nov 2005

Critical role of p53 gene

Fruit flies can live significantly longer, and remain healthy, when activity of the fly version of the tumor-suppressing protein p53 is reduced in nerve cells.

21 Nov 2005

Newly identified protein may help improve treatment for lung cancer

Researchers hope that a newly identified protein can one day help improve treatment for lung cancer. The findings are reported by researchers from Wake Forest University School of Medicine and colleagues in the Journal of the National Cancer Institute.

21 Nov 2005

Seasonal depression affects hamsters

A new study suggests that hamsters may suffer from symptoms of anxiety and depression during the dark days of winter, just as some humans do.

21 Nov 2005

Nanotechnology and biochemistry provide new way to study T cell signaling

Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley, combining nanotechnology with biochemistry, have created unique synthetic membranes that, for the first time ever, enable them to directly control signaling activity in living T cells from the immune system. Already their experiments have yielded surprising results.

21 Nov 2005

Warning labels on high-risk drugs ignored by doctors

In a survey of approximately 930,000 ambulatory care patients, researchers from the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care) and colleagues found that 42 percent received prescriptions for drugs with Black Box Warnings (BBW), the Food and Drug Administration's strongest label for high-risk medication.

21 Nov 2005

American physicians may be too liberal in their use of blood transfusions

In an analysis of some 24,000 patient records, the researchers found that Americans rushed to the hospital with heart attack symptoms have significantly higher rates of bleeding and transfusions after treatment than similar patients throughout the world.

21 Nov 2005

Africa worst hit by AIDS - 2.4m dead, 3.2m infected in sub-Sahara

According to a new UN report, levels of HIV infection in the Middle East and North Africa are increasing and there is an urgent need for better education and prevention strategies.

21 Nov 2005

Warnings on popular asthma drug could damage drug giant

The U.S. Food and Drug Administration (FDA) is recommending new restrictions on the asthma drug Advair.

21 Nov 2005

Women more sensitive to chronic stress than men

"It's generally understood that females respond more strongly to acute (immediate, short-term) stress than males," said Helmer Figueiredo, PhD, of UC's department of psychiatry. "Our research shows that this may also be the case in more clinically relevant chronic-stress conditions."

20 Nov 2005