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Genetic research offers insight into Sjögren's syndrome and the general developmental machinery of the immune system

By knocking out a single gene in mice, immunologists at Duke University Medical Center have mimicked a little-understood autoimmune disorder in humans.

21 Oct 2004

New medication to prevent colon cancer

A Stony Brook University researcher is testing a new form of aspirin--one that is much more potent than its commercially available counterpart, but with almost none of the side effects--to determine whether it can be used to prevent colon cancer in patients who are prone to the disease.

21 Oct 2004

Treatment with oestrogen to reduce the adult height of tall girls may cause fertility problems later in life

Research from Australia in this week’s issue of THE LANCET suggests that tall girls given oestrogen therapy in adolescence to reduce adult height are more likely to experience later fertility problems than the general population.

21 Oct 2004

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Researchers at Virginia Commonwealth University’s Massey Cancer Center received a prestigious award and a $600,000 grant from the V Foundation for Cancer Research, one of the nation’s leading organizations devoted exclusively to funding cancer research.

20 Oct 2004

Guidebook helps adults identify and cope with teen stress

Returning to school can be a stressful time, especially for teens. Many teens face stress from the new demands of school, puberty, changing relationships, family responsibilities and safety issues in their neighborhoods. However, teen stress is not always recognized by adults.

20 Oct 2004

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

A brain protein already known to play a central role in the "feast or fast" signaling that controls the urge to eat has now been found to influence appetite in a second way. The discovery identifies a potential new target for drugs against obesity.

19 Oct 2004

Launch of an internet-based HIV/AIDS training resource database

A major barrier to access to care for HIV/AIDS patients in resource limited settings -- the lack of trained healthcare providers -- is now eased with the launch of an internet-based clinical training resource database.

19 Oct 2004

Scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia

UCLA scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia, (A-T), a life-shortening disorder that devastates the neurological and immune systems of one in 40,000 young children.

19 Oct 2004

Cost cutting measures and patent expirations to propel the European generics and biogenerics market

The upcoming spate of patent expirations bodes well for the European generics market. The growing loss of patent protection on blockbuster brands over the next few years, coupled with the rising need to contain spiralling healthcare costs, is set to provide a fillip to market expansion.

19 Oct 2004

Discovery might improve design, effectiveness of anti-cancer drugs

Working with an enzyme that degrades anti-cancer drugs in humans, University of North Carolina at Chapel Hill biochemists and colleagues have made a discovery that they believe eventually could help improve such drugs’ design and effectiveness.

18 Oct 2004

Patients with chronic rhinosinusitis do not necessarily develop resistance to antibiotics

Patients with chronic rhinosinusitis (CRS, inflammation of the nasal passages and sinuses) do not necessarily develop resistance to antibiotics although they may be treated for long periods of time with these drugs

18 Oct 2004

One in four deaths among women with heart failure can be attributed to kidney problems

About one in four deaths among women with heart failure can be attributed to kidney problems, and more deaths are linked to renal insufficiency than to any other single risk factor, according to a new study in the Oct. 19, 2004 issue of the Journal of the American College of Cardiology.

18 Oct 2004

FDA issues warning on adolescent use of antidepressants

The Food and Drug Administration (FDA) has issued a Public Health Advisory announcing a multi-pronged strategy to warn the public about the increased risk of suicidal thoughts and behavior ("suicidality") in children and adolescents being treated with antidepressant medications.

18 Oct 2004

Researchers have found two areas of the brain that appear to compete for control over behavior

You walk into a room and spy a plate of gooey doughnuts dripping with chocolate frosting. But wait: You were saving your sweets allotment for a party later today. If it feels like one part of your brain is battling another, it probably is, according to a newly published study.

18 Oct 2004

Study underscores the relative safety of infliximab, when used properly

Rheumatoid arthritis patients receiving the recommended starting dose (3mg/kg) of infliximab (REMICADE®) have no more serious rate of infections than do patients taking methotrexate alone

18 Oct 2004

Presentation of the most recent and advanced work in the rapidly progressing field of fertility preservation

Each year approximately 50,000 women under the age of 40 are diagnosed with breast cancer. Treatments vary but most involve the administration of chemotherapeutic agents or radiation which can disrupt ovarian function or damage a patient’s eggs.

18 Oct 2004

COX-2 agents have influenced the way physicians prescribe rheumatology medication

COX-2 agents, with their perceived reduction in side effects, have contributed substantially to a dramatic increase in NSAIDs (non-steroidal anti-inflammatory drugs) prescription utilization and influenced the way physicians prescribe rheumatology medication

18 Oct 2004

Pneumococcal vaccinations help protect patients with rheumatoid arthritis against serious pneumococcal infections of the lungs, brain, blood, and ears

Rheumatoid arthritis patients have an approximately two-fold increased morbidity and mortality in infections compared to a population without the disease.

18 Oct 2004

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004

Significant steps to fight a deadly childhood muscle cancer

University of Utah scientists have taken significant steps to fight a deadly childhood muscle cancer by identifying some of the genetic events that cause the disease and then engineering mice that develop the tumors.

16 Oct 2004

Drugs News and Research

Genetic research offers insight into Sjögren's syndrome and the general developmental machinery of the immune system

New medication to prevent colon cancer

Treatment with oestrogen to reduce the adult height of tall girls may cause fertility problems later in life

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Guidebook helps adults identify and cope with teen stress

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

Launch of an internet-based HIV/AIDS training resource database

Scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia

Cost cutting measures and patent expirations to propel the European generics and biogenerics market

Discovery might improve design, effectiveness of anti-cancer drugs

Patients with chronic rhinosinusitis do not necessarily develop resistance to antibiotics

One in four deaths among women with heart failure can be attributed to kidney problems

FDA issues warning on adolescent use of antidepressants

Researchers have found two areas of the brain that appear to compete for control over behavior

Study underscores the relative safety of infliximab, when used properly

Presentation of the most recent and advanced work in the rapidly progressing field of fertility preservation

COX-2 agents have influenced the way physicians prescribe rheumatology medication

Pneumococcal vaccinations help protect patients with rheumatoid arthritis against serious pneumococcal infections of the lungs, brain, blood, and ears

Researchers have developed a novel drug-antidote pair

Significant steps to fight a deadly childhood muscle cancer

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