Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

New study associates commonly used diabetes drugs with pancreatic cancer risk

ndividuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida.

28 Mar 2013

Research findings could lead to new treatments for lung disorders in premature babies

Researchers at Yale School of Medicine have made major discoveries that could lead to new treatments for lung disorders in premature babies. In a mouse study, the team located key molecules that switch on stress pathways in preterm lung disorders, and also found that when parts of these pathways were blocked with a pain drug, lung damage was prevented or reversed.

21 Mar 2013

Study finds significant variation over diuretics use in BPD patients

Even though there is little data to support the extended use of diuretic medications to help reduce fluid build-up in the lungs of premature infants, researchers at Nationwide Children's Hospital have found significant variation in how babies receive these medications at hospitals across the nation.

20 Mar 2013

Special issue on colorectal cancer published in GIE: Gastrointestinal Endoscopy journal

In recognition of National Colorectal Cancer Awareness Month, GIE: Gastrointestinal Endoscopy has published a special issue for March on colorectal cancer.

20 Mar 2013

Screening healthy adults could potentially prevent rare genetic disorders

Millions of people unknowingly carry rare gene mutations that put them at high risk of developing preventable diseases such as colorectal cancer, breast cancer, and several catastrophic blood vessel disorders.

6 Mar 2013

Patients with Barrett's esophagus benefit from endoscope-based therapies

According to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, patients with Barrett's esophagus and early or pre-cancerous cells have been shown to significantly benefit from minimally invasive therapy delivered through an endoscope - a medical instrument used to look inside an organ or cavity in the body.

21 Feb 2013

Military women more likely to contract sexually transmitted infections: Study

As the number of women in the military increases, so does the need for improved gynecologic care. Military women may be more likely to engage in high-risk sexual practices, be less likely to consistently use barrier contraception, and, therefore, more likely to contract sexually transmitted infections (STIs), according to research recently released by a physician at Women & Infants Hospital of Rhode Island.

29 Jan 2013

Researchers unveil first maturation-based ‘disease in a dish’ model for ARVD/C

Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by 2012 Nobel Prize winner Shinya Yamanaka, M.D., Ph.D., helps solve this problem.

29 Jan 2013

Skin cells transformed into heart cells for research into cardiomyopathy

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28 Jan 2013

Evidence links HPV16 to focal cortical dysplasia type IIB

Researchers at Shriner's Hospital Pediatric Research Center at the Temple University School of Medicine, and the University of Pennsylvania have evidence linking the human papillomavirus 16 (HPV16) - the most common cause of cervical cancer - to a common form of childhood epilepsy.

28 Jan 2013

Study to determine prevalence of abnormal anal cytology and HPV in at-risk women

A basic connection of statistics lead a researcher at Women & Infants Hospital of Rhode Island to question whether women should be screened for anal cancer during a regular visit to the gynecologist, and what technique is most effective.

18 Jan 2013

Multiple birth hip dysplasia screening questioned

Ultrasound screening for developmental dysplasia of the hip is unnecessary in twins and triplets without signs of the condition, say UK researchers.

7 Jan 2013

Inovio, MVI collaborate to advance malaria vaccine development and new delivery technologies

The PATH Malaria Vaccine Initiative (MVI) and Inovio Pharmaceuticals, Inc. today announced a follow-on collaboration to advance malaria vaccine development and new vaccination delivery technologies.

7 Jan 2013

Umbilical cord stem cell therapy shows promise in infant BPD

Researchers have successfully used human umbilical cord stem cells to partially prevent damage and restore lung structure and function in an experimental animal model of bronchopulmonary dysplasia.

19 Dec 2012

NeoGenomics launches FISH assay for surveillance of patients with Barrett's Esophagus

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today it has validated and launched a laboratory developed Fluorescent in Situ Hybridization assay for the surveillance of patients with Barrett's Esophagus.

17 Dec 2012

Perthes’ disease link to congenital disorders revealed

Researchers have linked Perthes' disease with several congenital conditions, pointing to intra-uterine factors behind the development of the disease.

14 Dec 2012

Celgene announces results from REVLIMID plus VIDAZA phase II study on AML

Celgene International Sàrl today announced that results from a study evaluating the combination of REVLIMID (lenalidomide) plus VIDAZA (azacitidine) in patients 60 years or older with untreated acute myeloid leukemia (AML) were presented at the American Society of Hematology annual meeting in Atlanta, GA.

11 Dec 2012

Child psychiatrist from England named recipient of Lennox-Lombroso Award

The American Epilepsy Society has announced that David C. Taylor, lately Head of the Department of Psychiatry and Behavioural Sciences, University of Manchester, UK, and a pioneering child psychiatrist, has been named recipient of The William G. Lennox—Cesare T. Lombroso Award for 2012.

1 Dec 2012

Inovio's SynCon DNA vaccine effective at inducing CD8+ T cell responses specific to CMV

Inovio Pharmaceuticals, Inc. announced today that testing of multiple synthetic vaccine constructs for cytomegalovirus (CMV) induced robust T cells in mice, demonstrating the potential for a SynCon DNA vaccine to treat this virus that causes infant death and congenital abnormalities, is associated with cerebral palsy and brain tumors, and is the most common viral infection in organ transplant recipients. CMV is also associated with numerous inflammatory diseases and cancers, and is implicated in hypertension, a major risk factor for cardiovascular diseases.

26 Nov 2012

New research helps improve quality of life-saving blood transfusions for preterm babies

Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood.

26 Nov 2012