Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.
AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.
A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and pancreatic cyst fluids.
A study conducted by researchers at the University of São Paulo's Ribeirão Preto School of Medicine in Brazil, with support from the Sao Paulo Research Foundation - FAPESP , indicates that length of stay in the ICU is the factor that best explains some preterm babies' behavioral problems relating to emotional regulation, regardless of the degree of prematurity and the presence of bronchopulmonary dysplasia and retinopathy of prematurity (ROP).
Elevated pathogen colonization and a lack of bacterial diversity in the mouth were identified in people with precancerous lesions that could precede stomach cancer, finds a new study led by New York University College of Dentistry and New York University School of Medicine.
As the Trump administration and Republicans in Congress look to scale back Medicaid, many voters and state lawmakers across the country are moving to make it bigger.
Researchers at Drexel University have revealed that inhibiting the micro-RNA miR-34a significantly reduces bronchopulmonary dysplasia (BPD) in mice.
The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below. BE is a condition in which there are unusual changes to the cells lining the esophagus. It is believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD).
The lungs are one of the last organs to undergo full maturation in a baby's body. Children that are born very prematurely do not have fully developed lungs, and are therefore more susceptible to associated complications.
Over the past 30 years, squamous cell carcinoma of the anus (SCCA) is one of the few cancers with steadily rising incidence in the United States, with the most rapid increase seen in black men.
A team of engineers and pediatric orthopedic surgeons are using 3D printing to help train surgeons and shorten surgeries for the most common hip disorder found in children ages 9 to 16.
Premature babies treated with caffeine have better lung function in mid-childhood than preemies not treated with caffeine, according to a randomized controlled trial published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
It is almost axiomatic in medicine that the study of rare disorders informs the understanding of more common, widespread ailments.
Tests of cells collected from the umbilical cord blood vessel walls at birth can predict death or poor pulmonary outcomes in extremely preterm infants, say researchers at the University of Alabama at Birmingham.
As of this year, kids under the age of 15 only need 2 doses of HPV vaccine. New research out of Boston Medical Center, published online in the STD Journal, is the first published clinical evidence to support new recommendations by the Center for Disease Control and Prevention for a two-dose HPV vaccine to prevent genital warts.
Leti, a technology research institute of CEA Tech, today announced a European Union project to develop a nanotherapy targeting the molecules involved in inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis.
Artificial intelligence--commonly known as A.I.--is already exceeding human abilities. Self-driving cars use A.I. to perform some tasks more safely than people. E-commerce companies use A.I. to tailor product ads to customers' tastes quicker and with more precision than any breathing marketing analyst.
Findings published in the Journal of Pediatrics describe growth factors in cord blood that may identify premature infants at risk for bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) – an often fatal lung disease in which the vessels carrying blood from the heart to the lungs become narrowed and dysfunctional.
THE long-held belief that Omega-3 fats can help reduce chronic lung disease in pre-term babies has been debunked by researchers.
Thanatophoric dysplasia (TD) is an intractable disease designated by Ministry of Welfare, Health and Labor of Japan, causing severe abnormalities of bones and the brain.
While a first time kneecap dislocation can usually be treated non-surgically, recurring dislocations often necessitate surgical intervention. MPFL (medial patellofemoral ligament) reconstructions have become a common surgical option and have seen improved outcomes and a high rate of return to sport.