Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

Study sheds light on the mechanism of lung damage in premature babies

The lungs are one of the last organs to undergo full maturation in a baby's body. Children that are born very prematurely do not have fully developed lungs, and are therefore more susceptible to associated complications.

30 Sep 2017

Researchers find racial and gender disparities in survival of patients with anal cancer

Over the past 30 years, squamous cell carcinoma of the anus (SCCA) is one of the few cancers with steadily rising incidence in the United States, with the most rapid increase seen in black men.

9 Aug 2017

3D-printed models help shorten surgery time for common hip disorder in children

A team of engineers and pediatric orthopedic surgeons are using 3D printing to help train surgeons and shorten surgeries for the most common hip disorder found in children ages 9 to 16.

2 Aug 2017

Preemies treated with caffeine have better lung function in mid-childhood, study finds

Premature babies treated with caffeine have better lung function in mid-childhood than preemies not treated with caffeine, according to a randomized controlled trial published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

14 Jul 2017

Researchers who study HED identify mechanism that may be disrupted in male pattern baldness

It is almost axiomatic in medicine that the study of rare disorders informs the understanding of more common, widespread ailments.

8 Jun 2017

Biomarker may predict death or poor pulmonary outcomes in extremely preterm infants

Tests of cells collected from the umbilical cord blood vessel walls at birth can predict death or poor pulmonary outcomes in extremely preterm infants, say researchers at the University of Alabama at Birmingham.

22 May 2017

Two-dose HPV vaccine provides effective protection against genital warts

As of this year, kids under the age of 15 only need 2 doses of HPV vaccine. New research out of Boston Medical Center, published online in the STD Journal, is the first published clinical evidence to support new recommendations by the Center for Disease Control and Prevention for a two-dose HPV vaccine to prevent genital warts.

15 May 2017

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Leti, a technology research institute of CEA Tech, today announced a European Union project to develop a nanotherapy targeting the molecules involved in inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis.

12 May 2017

Artificial intelligence image detection technique offers low-cost, improved screening for cervical cancer

Artificial intelligence--commonly known as A.I.--is already exceeding human abilities. Self-driving cars use A.I. to perform some tasks more safely than people. E-commerce companies use A.I. to tailor product ads to customers' tastes quicker and with more precision than any breathing marketing analyst.

24 Apr 2017

Growth factors in cord blood may help identify preemies at risk for fatal lung disease

Findings published in the Journal of Pediatrics describe growth factors in cord blood that may identify premature infants at risk for bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) – an often fatal lung disease in which the vessels carrying blood from the heart to the lungs become narrowed and dysfunctional.

6 Apr 2017

Omega-3 fats fail to reduce risk of chronic lung disease in pre-term babies, study finds

THE long-held belief that Omega-3 fats can help reduce chronic lung disease in pre-term babies has been debunked by researchers.

31 Mar 2017

Researchers use animal model to study brain abnormality in human TD patients

Thanatophoric dysplasia (TD) is an intractable disease designated by Ministry of Welfare, Health and Labor of Japan, causing severe abnormalities of bones and the brain.

17 Mar 2017

MPFL reconstructions safe and effective for treating patients with trochlear dysplasia, study shows

While a first time kneecap dislocation can usually be treated non-surgically, recurring dislocations often necessitate surgical intervention. MPFL (medial patellofemoral ligament) reconstructions have become a common surgical option and have seen improved outcomes and a high rate of return to sport.

16 Mar 2017

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow.

23 Nov 2016

Two Staffordshire hospitals introduce pioneering technology to improve cervical cancer diagnosis

Two hospitals in Staffordshire have introduced a pioneering new technology designed to improve the speed and accuracy in diagnosing pre-cancerous conditions of the cervix.

From Zilico 5 Oct 2016

Steroid treatment linked to increased risk of retinopathy in very low birth weight infants

Because of the beneficial effect of corticosteroids on lung function, especially in infants who are ventilator dependent, corticosteroids are, at times, administered to very low birth weight neonates to treat established or evolving lung disease. However, it has long been suspected that steroids may have negative neurodevelopmental effects on very premature infants.

16 Aug 2016

Disordered airway microbiome at birth may be linked to severe neonatal lung disease

In contrast to the general belief that the airways of an infant are sterile until after birth, University of Alabama at Birmingham researchers and colleagues have found that the infant airway is already colonized with bacteria or bacterial DNA when a baby is born -- and this is true for infants born as early as 24 weeks gestation.

5 Aug 2016

Study offers new hope for preventing chronic lung disease in premature infants

By triggering a process called autophagy -- in which cells literally engulf their own insides --researchers from Drexel University and Yale University were able to decrease lung injury in mice that were exposed to high concentrations of oxygen.

20 Jul 2016

Women with SLE may have increased cervical cancer risk

The results of a study presented today at the European League Against Rheumatism Annual Congress found a doubled risk of pre-malignant cervical changes, and potentially also an increased risk of cervical cancer, among women with Systemic Lupus Erythematosus (SLE) compared to the general female population.

10 Jun 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016