E. coli News and Research

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E. coli or Escherichia coli is the name of a type of bacteria that lives in your intestines. Most types of E. coli are harmless. However, some types can make you sick and cause diarrhea. One type causes travelers' diarrhea. The worst type of E. coli causes bloody diarrhea, and can sometimes cause kidney failure and even death. These problems are most likely to occur in children and in adults with weak immune systems. You can get E. coli infections by eating foods containing the bacteria. To help avoid food poisoning and prevent infection, handle food safely. Cook meat well, wash fruits and vegetables before eating or cooking them, and avoid unpasteurized milk and juices. You can also get the infection by swallowing water in a swimming pool contaminated with human waste. Most cases of E. coli infection get better without treatment in 5 to 10 days.

An antibiotic, Tigecycline produces 74 percent cure rate in cSSSI patients

An antibiotic, currently being tested in clinical trials, produced a 74 percent cure rate for hospitalized patients with possibly life-threatening, complicated skin and skin structure infections (cSSSI).

23 May 2004

Signs of liver disease also improve in conjunction with alterations to gut flora

Some cirrhotic patients develop brain dysfunction, called hepatic encephalopathy, which causes deficits in behavior, intelligence, consciousness and neuromuscular function.

14 May 2004

Protein in the male reproductive tract is a potent anti-bacterial agent

Scientists at the University of North Carolina at Chapel Hill have found that a protein they discovered three years ago in the male reproductive tract is a potent anti-bacterial agent.

6 May 2004

Scientists have unraveled the behavior of one key component of bacteria

The researchers studied a mechanism of action they call the "magic spot" – an important regulator of gene expression. They describe their results in the current issue of the journal Cell.

29 Apr 2004

Pennsylvania's restaurants, stadiums, bars and supermarkets are adjusting to revised food safety requirements

Pennsylvania's restaurants, stadiums, bars and supermarkets are adjusting to revised food safety requirements in the Pennsylvania Food Code, according to a specialist in Penn State's College of Agricultural Sciences.

27 Apr 2004

Genetically engineered bugs to fight cancer

GENETICALLY engineered bacteria could become the latest weapons against cancer, Cancer Research UK scientists suggest in a study published today 22nd April 2004.

22 Apr 2004

Poultry litter harbors agents that generate antibiotic multi-resistance

They found that poultry litter – a ubiquitous part of large broiler operations – harbors a vastly larger number of microbial agents that collect and express resistance genes than was previously known.

19 Apr 2004

76 million people get sick in US, 300,000 are hospitalized, and 5,000 die from foodborne illness

Foodborne illnesses have a major public health impact in the United States. It is estimated that each year in the United States, 76 million people get sick, more than 300,000 are hospitalized, and 5,000 die as a result of foodborne illnesses, primarily the very young, elderly, and the immunocompromised.

18 Apr 2004

Scientists will debate E.coli and the adaption by micro-organisms to modern day drugs

This debate will centre around why humans are constantly under attack from infectious diseases such as E.coli despite medical advances in vaccinations and antibiotics, and how micro-organisms that cause disease evolve and adapt quickly to the many barriers that our bodies' anti-infection strategies and our drugs industry throw at them.

16 Apr 2004

New process to extract proteins from membranes by using chemicals

Proteins are complex compounds that are essential for the growth and repair of tissue. While scientists understand much about the structure and stability of water-soluble proteins that ‘float’ around in humans, they know very little about the shape and stability of proteins that are embedded, or folded, into the lipid membrane of cells. Such membrane proteins make up about 30 percent of all proteins in the body.

8 Apr 2004

Analysis of Bacterial Genomes Begins to Unravel Complex Story of Metabolic Evolution

In a paper published in the current issue of the journal Molecular Biology and Evolution , Arizona State University biochemists Jason Raymond, Christopher Staples and Robert Blankenship and Rice University's Janet Siefert do an analysis of the genomes of a large group of bacteria and archaea, comparing in particular similar genes that produce the protein nitrogenase.

7 Apr 2004

Scientists have discovered that a non-genetic molecular process can effect cell behaviour

Genetic mutations, sudden, random and usually harmful changes to the structure of a gene, are only one factor that determines the ultimate fate of a cell. Chicago scientists have discovered that a non-genetic molecular process also can play a role, and that experimenters can influence this process in bacteria, they report in the April 1 issue of the journal Nature.

1 Apr 2004

Scientists seek cause for what makes good cell go bad

Genetic mutations--sudden, random and usually harmful changes to the structure of a gene--are only one factor that determines the ultimate fate of a cell. Chicago scientists have discovered that a non-genetic molecular process also can play a role, and that experimenters can influence this process in bacteria, they report in the April 1 issue of the journal Nature.

31 Mar 2004

Novel uses for bacterial cellulose, artificial blood vessels, bioengineered wound dressing

New and unique products created from bacterial cellulose — from electronic paper to treatment for wounds — will highlight a one-day symposium at the 227th national meeting of the American Chemical Society, the world's largest scientific society.

30 Mar 2004

New drug to treat urinary tract infections, a step closer

Depomed, Inc. today announced top line results from the Phase III clinical trial of its Ciprofloxacin GR, an extended release formulation of ciprofloxacin HCl, which is used to treat urinary tract infections. The data confirmed Phase II results, demonstrating that Depomed's once-daily Ciprofloxacin GR eliminated the organisms responsible for urinary tract infections as effectively as twice-daily CIPRO(R), but with fewer gastrointestinal side effects, specifically fewer incidences of nausea and diarrhea.

22 Mar 2004