Elephantiasis News and Research

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Elephantiasis is a disease that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals.

Anacor, UCSF and NYBC collaborate to discover drug therapies for river blindness

Anacor Pharmaceuticals, the University of California San Francisco (UCSF) Sandler Center and the Lindsley F. Kimball Research Institute (LFKRI) of the New York Blood Center (NYBC) today announced the establishment of a research and development collaboration to discover new drug therapies for the treatment of river blindness (onchocerciasis), a parasitic disease that is the second leading cause of infectious blindness worldwide, and is most prevalent in Africa.

1 Dec 2010

Eisai signs statement of intent with WHO to supply medicine for treatment of lymphatic filariasis

Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito) announced today that it has signed a statement of intent with the World Health Organization to supply free of charge a primary medicine for the treatment of lymphatic filariasis.

19 Nov 2010

Discovery of anti-parasitic drug mechanism could lead to new treatments for filarial diseases

In a major breakthrough that comes after decades of research and nearly half a billion treatments in humans, scientists have finally unlocked how a key anti-parasitic drug kills the worms brought on by the filarial diseases river blindness and elephantitis.

11 Nov 2010

Drosophila fly study may aid in staving off diseases in humans using defensive bacteria

It has been a basic principle of evolution for more than a century that plants and animals can adapt genetically in ways that help them better survive and reproduce.

12 Jul 2010

Merck proposes to initiate Phase II proof-of-concept clinical study of posaconazole for chronic Chagas disease

Merck today announced plans to initiate a Phase II investigational proof-of-concept clinical study to evaluate its oral antifungal agent posaconazole for the treatment of chronic Chagas disease. Chagas disease results from infection with the parasite Trypanosoma cruzi that is spread by biting insects. The disease is estimated to affect approximately eight million people in Latin America, of whom approximately 30-40 percent will develop serious cardiac disease, digestive disease, or both as a result of this infection.

24 Jun 2010

Global Programme seeks to eliminate Lymphatic Filariasis by 2020

Representatives from more than 50 countries attended the Sixth Meeting of the Global Alliance to Eliminate Lymphatic Filariasis (GAELF) in Seoul last week, to review the progress of the Global Programme to Eliminate Lymphatic Filariasis (Global Programme), which seeks to eliminate the disease by 2020.

14 Jun 2010

Elephantiasis and river blindness: MSU researcher receives $2M for reformulating flubendazole

In an effort to eliminate the tropical diseases elephantiasis and river blindness, a Michigan State University researcher has been awarded $2 million to reformulate an existing drug that could stop the debilitating diseases in their tracks.

5 Feb 2010

UK DFID awards CNTD £10M in elimination of elephantiasis initiative

The Centre for Neglected Tropical Diseases (CNTD) at the Liverpool School of Tropical Medicine has been awarded £10 million by the UK Department for International Development (DFID) to support endemic countries in tackling lymphatic filariasis (LF) - a crippling disease more commonly known as elephantiasis.

3 Dec 2009

DNA "barcodes" used to map mosquito species in West Africa that spread lymphatic filariasis

New biotechnologies that allow scientists to quickly and accurately distinguish species based on a simple DNA analysis are being creatively deployed for the first time in the war against a major global disease.

29 Apr 2009

Doxycycline effective against filariasis in Southeast Asia

Doxycycline alone is more effective against the most common form of filariasis in Southeast Asia than the standard treatment, with significantly fewer side effects, according to a new study published in the May 1 issue of Clinical Infectious Diseases and currently available online.

10 Apr 2008

Experts call for a global fund to combat neglected tropical diseases

An international team of tropical disease control experts has urged the global health and development community, and particularly the G8 leaders, to establish a new financing mechanism to combat the neglected tropical diseases (NTDs) of poverty.

28 Mar 2008

Study paves way for mass co-delivery of three antiparasitic drugs

Findings from a new study in Zanzibar, published January 23 in PLoS Neglected Tropical Diseases, pave the way for the World Health Organization (WHO) to recommend the mass co-delivery of three anti-parasitic drugs for the first time.

24 Jan 2008

Neglected tropical diseases, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis and schistosomiasis

Though little known to most Americans, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis, schistosomiasis and other so-called neglected tropical diseases are responsible for severe health burdens, especially among the world's poorest people.

28 Dec 2007

Lymphatic filariasis causes devastating social and economic losses

Sri Lankans infected with lymphatic filariasis (also known as elephantiasis) experience severe loss of income, social isolation, and devastating stigma resulting in emotional distress, delayed diagnosis, and avoidance of treatment.

22 Nov 2007

Mass drug treatment for elephantiasis is affordable compared with other public health programs

Once-yearly administration of two anti-parasitic drugs to control lymphatic filariasis (elephantiasis) costs just $0.06 to $2.23 per person treated, making it comparatively inexpensive, according to a major new international study of treatment costs.

31 Oct 2007

Brugia malayi's secrets revealed

An international team of researchers has revealed the genetic secrets of one of the world's most debilitating human parasites, Brugia malayi (B. malayi), which the World Health Organization estimates has seriously incapacitated and disfigured more than 40 million people around the globe.

21 Sep 2007

Scientists solve genetic code of parasitic worm that causes elephantiasis

More than 150 million people worldwide are infected with filarial parasites -- long, thread-like worms that can live for years inside the human body and cause severe, debilitating diseases such as elephantiasis.

21 Sep 2007

Drug-enriched salt could prevent elephantiasis

Though little known outside the developing world, the disease called lymphatic filariasis wreaks havoc on millions of people by causing their limbs and genitals to fill with fluid and swell monstrously - the symptom commonly known as elephantiasis.

1 Mar 2007

WHO unveils new strategy to fight some of the most neglected tropical diseases

The World Health Organization (WHO) and a group of more than 25 partner organizations unveiled a new strategy to fight some of the most neglected tropical diseases that destroy the lives and health of poor people.

26 Oct 2006

Waterborne infectious diseases could soon be consigned to history

Waterborne infectious diseases, which bring death and illness to millions of people around the world, could largely be consigned to history by 2015 if global health partnerships integrate their programmes, according to Alan Fenwick writing in Science.

28 Aug 2006