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Patient and nurse safety may be related by common causes

A safe working environment for nurses is also a safe environment for the patients in their care, according to a new study led by public health researchers at Drexel University. Researchers, led by Dr. Jennifer Taylor, an assistant professor in Drexel's School of Public Health, found that safety climate was associated with both patient and nurse injuries, suggesting that patient and nurse safety may be linked outcomes.

8 Nov 2011

Doctors may stop anti-TNF medications for RA patients before surgery to reduce disease flares

As guidelines recommend, doctors appear to be stopping anti-TNF medications before surgery, but may be doing so far sooner than is necessary, according to a new study by researchers at Hospital for Special Surgery. These medications are used to treat a variety of inflammatory diseases, including rheumatoid arthritis, and better timing of withdrawal prior to surgery might minimize the risk of disease flares.

6 Nov 2011

Enoxaparin can reduce risk of VTE in plastic surgery patients

For plastic surgery patients at high risk, treatment with the anticoagulant (blood-thinning) drug enoxaparin can reduce the risk of serious blood clot-related complications called venous thromboembolism (VTE), reports a study in the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

28 Oct 2011

Potential deadly consequences of silicone injections

Reports of adverse events, including death, from silicone injections for cosmetic purposes have been increasing in both medical and consumer literature. In studies presented at CHEST 2011, the 77th annual meeting of the American College of Chest Physicians (ACCP), in Honolulu, Hawaii, researchers from Louisiana State University Health Sciences Center in New Orleans, Louisiana; Henry Ford Hospital in Detroit, Michigan; and Olive View-UCLA Medical Center in Sylmar, California all reported cases of near-lethal and lethal silicone use.

24 Oct 2011

Change in CT protocols could decrease radiation dose to the breast and lungs

Carefully consider the radiation dose to the breast and lungs before deciding which CT protocol to use for thoracic imaging of individual patients, a new study cautions.

1 Oct 2011

New AAOS guideline recommends how to reduce DVT, PE after joint replacement surgery

An updated clinical practice guideline released last week by the American Academy of Orthopaedic Surgeons (AAOS) Board of Directors recommends how to reduce the likelihood of blood clots after hip or knee replacement surgery, procedures that more than 800,000 Americans undergo each year. The new guideline suggests use of preventive treatments and advises against routinely screening patients after surgery using ultrasound imaging.

1 Oct 2011

African American patients more likely to receive replacement surgery in low-quality hospitals

Racial minorities have reduced access to high-quality joint replacement care, according to Dr. Xueya Cai and colleagues from the University of Iowa in the US. Their work, published online in Springer's journal Clinical Orthopaedics and Related Research, shows that African American patients are more likely than Caucasians to receive total knee arthroplasty (or replacement surgery) in low-quality hospitals.

14 Sep 2011

Genentech submits vismodegib NDA to FDA for treatment of advanced basal cell carcinoma

Genentech, a member of the Roche Group, today announced that the company has submitted a New Drug Application for vismodegib to the U.S. Food and Drug Administration (FDA) for the treatment of people with advanced basal cell carcinoma (BCC) for whom surgery is considered inappropriate.

12 Sep 2011

FDA panel votes 9-2 in favor of new blood thinner drug

A new stroke preventer from Bayer and Johnson & Johnson – Xarelto moved one step closer to U.S. approval, but questions remained about restrictions on labeling and the need for more studies.

9 Sep 2011

Cardiovascular and Renal Drugs Advisory Committee recommends FDA approval of J&JPRD's rivaroxaban

Johnson & Johnson Pharmaceutical Research and Development, L.L.C. (J&JPRD) announced today that the U.S. Food and Drug Administration's (FDA) Cardiovascular and Renal Drugs Advisory Committee recommended approval of rivaroxaban, a novel, once-daily, oral anticoagulant, for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

9 Sep 2011

FDA stalls the blood-thinner Xarelto’s approval citing inadequate evidence

The Food and Drug Administration (FDA) said in a staff report released today that “there is insufficient information about the drug to determine whether it is safe for use with its proposed labeling.” Their report questions its safety and effectiveness, saying a new study is needed.

6 Sep 2011

Dabigatran etexilate superior to warfarin for stroke prevention in AF patients

New data from two RE-LY trial sub-group analyses show that dabigatran etexilate provides consistent benefits in stroke in atrial fibrillation (AF) compared to well-controlled warfarin, irrespective of whether patients use antiplatelet or other concomitant therapies, such as the anti-arrhythmics amiodarone or verapamil.

29 Aug 2011

ELIQUIS better than warfarin in reduction of stroke, major bleeding, and mortality

Bristol-Myers Squibb Company and Pfizer Inc. today announced the main results of the Phase 3 clinical trial ARISTOTLE, which evaluated ELIQUIS compared to warfarin for the prevention of stroke or systemic embolism in 18,201 patients with atrial fibrillation and at least one risk factor for stroke.

29 Aug 2011

Apixaban superior to warfarin in preventing stroke and systemic embolism

A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation.

29 Aug 2011

BIPI to launch dabigatran etexilate Phase II trial in patients with mechanical heart valves

Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) today announced plans to launch RE-ALIGN, a global, Phase II trial evaluating the safety and pharmacokinetics of dabigatran etexilate in 400 patients who have mechanical heart valves.

26 Aug 2011

Patients with SVT more likely to develop venous thromboembolism

Patients with clinically diagnosed superficial vein thrombosis (SVT), a blood clot in the veins just beneath the skin that commonly resolves on its own without treatment, are four to six times more likely to develop venous thromboembolism (VTE), a dangerous, often life-threatening condition, according to study results published today in Blood, the Journal of the American Society of Hematology.

18 Aug 2011

New tool can identify patients at high risk of venous thromboembolism

A new risk prediction tool can identify patients at high risk of serious blood clots (known as venous thromboembolism) who might need preventative treatment, says a study published on bmj.com today.

17 Aug 2011

Current Medical Research & Opinion publishes new data on EVISTA for postmenopausal osteoporosis

Eli Lilly and Company today announced that data on EVISTA® (raloxifene HCl tablets) therapy for more than three years was published online in Current Medical Research & Opinion.

10 Aug 2011

Curis second quarter net loss increases to $4.9 million

Curis, Inc., a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today reported its financial results for the second quarter ended June 30, 2011.

28 Jul 2011

Hip and knee replacement surgery linked to increased risk of clot development

When tennis star Serena Williams underwent emergency treatment for a pulmonary embolism earlier this year, the world's attention was drawn to this often fatal medical condition which, although surprisingly not uncommon, is unfamiliar to most men and women.

28 Jul 2011

Embolism News and Research

Patient and nurse safety may be related by common causes

Doctors may stop anti-TNF medications for RA patients before surgery to reduce disease flares

Enoxaparin can reduce risk of VTE in plastic surgery patients

Potential deadly consequences of silicone injections

Change in CT protocols could decrease radiation dose to the breast and lungs

New AAOS guideline recommends how to reduce DVT, PE after joint replacement surgery

African American patients more likely to receive replacement surgery in low-quality hospitals

Genentech submits vismodegib NDA to FDA for treatment of advanced basal cell carcinoma

FDA panel votes 9-2 in favor of new blood thinner drug

Cardiovascular and Renal Drugs Advisory Committee recommends FDA approval of J&JPRD's rivaroxaban

FDA stalls the blood-thinner Xarelto’s approval citing inadequate evidence

Dabigatran etexilate superior to warfarin for stroke prevention in AF patients

ELIQUIS better than warfarin in reduction of stroke, major bleeding, and mortality

Apixaban superior to warfarin in preventing stroke and systemic embolism

BIPI to launch dabigatran etexilate Phase II trial in patients with mechanical heart valves

Patients with SVT more likely to develop venous thromboembolism

New tool can identify patients at high risk of venous thromboembolism

Current Medical Research & Opinion publishes new data on EVISTA for postmenopausal osteoporosis

Curis second quarter net loss increases to $4.9 million

Hip and knee replacement surgery linked to increased risk of clot development

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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