Encephalopathy News and Research

RSS

Phase 2a clinical trial describes safety and efficacy of dendrimer nanotherapy in severe COVID-19 patients

A multicenter, randomized, placebo-controlled phase 2a clinical trial has recently been conducted to evaluate the efficacy of a nanotherapeutic compound OP-101 in treating severe COVID-19 patients.

21 Jul 2022

Adding erythropoietin to cooling therapy shows no added benefits for newborns with birth asphyxia

Adding erythropoietin to cooling therapy for term newborns with birth asphyxia has no benefit over cooling therapy alone, a study published today in the New England Journal of Medicine.

14 Jul 2022

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Prion diseases are incurable, deadly neurological disorders that can affect both humans and animals–including Creutzfeldt-Jakob Disease (CJD) in people, Bovine Spongiform Encephalopathy (also known as Mad Cow Disease) and Chronic Wasting Disease found in deer.

13 Jul 2022

Researchers unravel the functioning of antibodies in autoimmune encephalitis

Using a state-of-the-art method, researchers at DZNE and the University of Texas have succeeded for the first time at unraveling the effects of autoimmune antibodies, that are directed against the brain, in detail at the atomic level.

8 Jul 2022

Neuropsychiatric symptoms prevalent in over 50% of monkeypox infections according to new research

Scientists have recently conducted a systematic review and meta-analysis to assess the types and prevalence of neurological and psychiatric symptoms associated with monkeypox virus infection in humans.

7 Jul 2022

Influenza vaccination may provide protective effect against Alzheimer’s disease

Researchers compared Alzheimer's Disease development risks among recipients and non-recipients of intramuscularly administered influenza vaccines.

5 Jul 2022

Elevated cerebrospinal fluid biomarkers of neuroinflammation in NeuroCOVID patients

A new research paper studied several biomarkers associated with neuronal injury, neuroinflammation, and neurodegeneration in NeuroCOVID adults who experienced a CNS syndrome during acute SARS-CoV-2 infection.

4 Jul 2022

The effects and mechanisms of SARS-CoV-2 on the nervous system

Researchers reviewed the neurologic manifestations associated with SARS-CoV-2.

30 Jun 2022

APOEε4 may confer increased risk for CTE-related neuropathological outcomes among older adults with repetitive head impacts

How could two individuals who both played football for 10 years and developed CTE have different disease severity? How could some individuals develop dementia in their 50's while other never develop dementia at all? Perhaps the answer lies in their genes.

27 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Assessing neurological symptoms present in long COVID patients

Researchers assessed the symptoms of neurological post-acute sequelae of SARS-CoV-2 infection (neuro-PASC) among patients with and without neurologic disorders.

17 Jun 2022

New research provides credible estimates for prevalence of Alzheimer’s-like brain disorder

New National Institutes of Health-funded research shows that the prevalence of brain changes from Limbic-predominant Age-related TDP-43 Encephalopathy (LATE) may be roughly 40% in older adults and as high as 50% in people with Alzheimer's disease.

13 Jun 2022

Study provides the most definitive assessment of new non-Alzheimer’s dementia

Researchers from the University of Kentucky's Sanders-Brown Center on Aging say a paper recently published in Acta Neuropathologica is the most definitive assessment yet of the prevalence of a form of dementia classified in 2019 and now known as LATE.

13 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Study highlights the need for liver cirrhosis patients to be educated on hepatic venous pressure gradient

Just like the hypertension that people develop when their blood pressure increases, the increase of blood pressure in the main vein that supplies blood to the liver, called the portal vein, is also a dangerous situation.

31 May 2022

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Research may lead to more effective interventions for hypoxic-ischemic encephalopathy

One of the most common causes of disability or death in newborns is a lack of oxygen or blood flow in the brain during labor or delivery.

11 May 2022

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

A new study has focused on the microcirculatory factors associated with neurological complications of COVID-19.

10 May 2022

Approximately 13% of hospitalized COVID patients have serious neurologic symptoms

In a recent study in the journal Critical Care Explorations, the Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry was used to record significant neurologic signs of SARS-CoV-2 infection, as well as prehospital risk factors and outcomes.

9 May 2022