Endocrine News and Research

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Bristol-Myers Squibb announces positive results from Phase 2 study of ipilimumab in patients with NSCLC

Bristol-Myers Squibb Company today announced positive results from a randomized Phase 2 study evaluating ipilimumab in combination with standard chemotherapy in previously untreated patients with advanced non-small cell lung cancer.

21 May 2010

Women exposed prenatally to BPA or DES at increased risk of breast cancer: Study

A study in mice reveals that prenatal exposure to endocrine-disrupting chemicals, like bisphenol-A and diethylstilbestrol, may program a fetus for life. Therefore, adult women who were exposed prenatally to BPA or DES could be at increased risk of breast cancer, according to a new study accepted for publication in Hormones & Cancer, a journal of The Endocrine Society.

21 May 2010

Zebrafish may help scientists reveal function of mysterious enzyme linked to steroid cortisol

Michael E. Baker, PhD, a researcher at the University of California, San Diego School of Medicine has discovered that zebrafish - an important animal model in disease and environmental studies - could provide the means to help scientists eventually reveal the function of a mysterious enzyme linked to the steroid cortisol, and found in the human brain.

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

i3 completes acquisition of ChinaGate

i3, a global life sciences services company and subsidiary of Ingenix, has acquired ChinaGate, a contract research organization that provides product-development regulatory services for pharmaceutical, medical device and biotechnology companies looking to enter and access the Chinese market.

19 May 2010

Choir singing induces state of stimulated regeneration in IBS patients

A Swedish investigation has compared choir singing and group discussion in irritable bowel syndrome in the current issue of Psychotherapy and Psychosomatics.

19 May 2010

President's Cancer Panel recommends home filtering devices to decrease exposure to cancer-causing agents

In its official annual report, the President's Cancer Panel is recommending that people use home filtering devices to decrease exposure to cancer-causing agents.

18 May 2010

Research sheds light on early embryogenesis, genetic disease

Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births.

15 May 2010

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Researchers studying the common genetic disorder chromosome 22q.11 deletion syndrome have identified key proteins that act together to regulate early embryonic development. One protein is essential to life; in animal studies, embryos without the protein do not survive past the first few days of gestation.

13 May 2010

FDA approves Aeterna Zentaris' AEZS-108 IND for bladder cancer

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that the U.S. Food and Drug Administration (FDA) has approved the Company's Investigational New Drug (IND) application for its doxorubicin targeted conjugate compound, AEZS-108, in luteinizing hormone releasing hormone (LHRH) receptor positive urothelial (bladder) cancer.

12 May 2010

Personalized treatments for thyroid disorders to be presented at ATA meeting

Internationally recognized thyroid disease experts will meet to discuss "Thyroid Disorders in the Era of Personalized Medicine" May 13 - 16 in Minneapolis, Minnesota at the American Thyroid Association's (ATA) (www.thyroid.org) Spring Meeting to be held at the Minneapolis Hyatt Regency Hotel.

11 May 2010

BIOTX introduces Estrofil menopause supplements in North America

BIOTX Limited – a manufacturer and developer of dietary supplements based on Traditional Chinese Medicine, today launched Estrofil in North America - an all-natural nutritional menopause supplement for the relief of menopausal symptoms. This new menopause natural remedy is not estrogen or hormone replacement therapy.

10 May 2010

Imprinted genes may be the root cause of gender specific diseases, says study

Pregnancy places competing demands on a mother's physiology: Her body wants to produce a strong healthy baby but not at the expense of her own health. Some of the genes that she passes on to her child therefore try to protect her own body from excessive demands from her child.

7 May 2010

New study shows single night of partial sleep deprivation can induce insulin resistance

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism, just one night of short sleep duration can induce insulin resistance, a component of type 2 diabetes.

6 May 2010

Obesity epidemic may be flattening out - still much to be done

The prevalence of childhood obesity might be stabilising in developed countries, but there is still much to be done to combat this major threat to health, according to a Seminar published on Online First and in an upcoming issue of The Lancet.

6 May 2010

Single night of partial sleep deprivation induces insulin resistance in healthy people

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), just one night of short sleep duration can induce insulin resistance, a component of type 2 diabetes.

5 May 2010

Study shows training in rhythmic gymnastics improves bone health in adolescent girls

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism, long-term elite rhythmic gymnastics exerts positive effects on volumetric bone density and bone geometry in adolescent girls.

5 May 2010

Merck reports non-GAAP EPS of $0.83 for first-quarter 2010

Merck & Co., Inc. today announced financial results for the first quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the first quarter of $0.83, which excludes purchase accounting adjustments, merger-related expenses and restructuring costs, as well as a tax charge related to the recently enacted health care reform legislation. First-quarter GAAP EPS was $0.09.

4 May 2010

Researchers evaluate efficacy of GKRS in patients with pituitary adenoma

In 2009, it was estimated that a total of 22,070 new cases of brain and other CNS tumors were diagnosed. Pituitary adenomas represent one of the most common brain tumors. Large studies report that approximately 10-20 percent of the population harbors a pituitary tumor. According to the Central Brain Tumor Registry of the United States, 13.4 percent of all brain and CNS tumors diagnosed in 2009 were located in the pituitary.

4 May 2010

Obese men more likely to have low testosterone than non-obese men: HIM study

Obesity, a condition linked to heart disease and diabetes, now appears to be associated with another health problem, but one that affects men only -- low testosterone levels.

4 May 2010

Endocrine News and Research

Bristol-Myers Squibb announces positive results from Phase 2 study of ipilimumab in patients with NSCLC

Women exposed prenatally to BPA or DES at increased risk of breast cancer: Study

Zebrafish may help scientists reveal function of mysterious enzyme linked to steroid cortisol

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

i3 completes acquisition of ChinaGate

Choir singing induces state of stimulated regeneration in IBS patients

President's Cancer Panel recommends home filtering devices to decrease exposure to cancer-causing agents

Research sheds light on early embryogenesis, genetic disease

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

FDA approves Aeterna Zentaris' AEZS-108 IND for bladder cancer

Personalized treatments for thyroid disorders to be presented at ATA meeting

BIOTX introduces Estrofil menopause supplements in North America

Imprinted genes may be the root cause of gender specific diseases, says study

New study shows single night of partial sleep deprivation can induce insulin resistance

Obesity epidemic may be flattening out - still much to be done

Single night of partial sleep deprivation induces insulin resistance in healthy people

Study shows training in rhythmic gymnastics improves bone health in adolescent girls

Merck reports non-GAAP EPS of $0.83 for first-quarter 2010

Researchers evaluate efficacy of GKRS in patients with pituitary adenoma

Obese men more likely to have low testosterone than non-obese men: HIM study

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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