Endocrine News and Research

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Breakthrough in thyroid cancer may enable more targeted risk assessment and earlier intervention

Scientists at deCODE genetics presented the discovery of two single letter variations in the sequence of the human genome (SNPs) conferring substantial increased risk of thyroid cancer.

8 Feb 2009

Study tests salsalate anti-inflammatory for poorly controlled type 2 diabetes

Researchers in 20 medical centers across the country are enrolling adults with type 2 diabetes who have poorly controlled blood glucose to participate in a clinical study, Targeting Inflammation with Salsalate in Type 2 Diabetes (TINSAL-T2D).

5 Feb 2009

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and its partner Newron Pharmaceuticals SpA has announced that the first Phase III trial of investigational agent safinamide as adjunctive therapy to levodopa (study 016) met its primary endpoint by increasing daily "ON" time in mid- to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours.

5 Feb 2009

Vitamin D related to muscle power, force, velocity and jump height in adolescent girls

Vitamin D is significantly associated with muscle power and force in adolescent girls, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism ( JCEM ).

3 Feb 2009

Growth hormone treatment for six months after weight loss surgery prevents loss of muscle mass

Growth hormone treatment for six months after weight loss surgery reduces patients' losses in lean body mass and skeletal muscle mass, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Feb 2009

Hormone level during pregnancy may identify women at risk for postpartum depression

Women who have higher levels of a hormone produced by the placenta midway through their pregnancy appear more likely to develop postpartum depression, according to a report in the February issue of Archives of General Psychiatry.

2 Feb 2009

Bioidentical hormone facts and perspectives

Public confusion of the benefits and risks of hormone therapy was highlighted once again this week on The Oprah Winfrey Show.

2 Feb 2009

Bipolar disorders linked to increased risk of early death from medical illness

Bipolar disorders appear to increase the risk of early death from a medical illness, according to a literature review study published as the lead article this week in the journal Psychiatric Services.

2 Feb 2009

Short intense exercise best way to lower risk of diabetes

A regular high-intensity, three-minute workout has a significant effect on the body's ability to process sugars.

29 Jan 2009

Osteoporosis? Look out for depression

A review article which is published in the current issue of the European Journal Psychotherapy and Psychosomatics analyzes the relationship between depression and bone metabolism.

19 Jan 2009

Prenatal exposure to environmental pollutants linked to higher BMI in toddlers

A new study reveals an association between prenatal exposure to environmental pollutants and elevated body mass index (BMI) during the first three years of life, as reported in the January 2009 issue of the peer-reviewed journal Environmental Health Perspectives (EHP).

15 Jan 2009

Smoking during pregnancy impacts thyroid function of mother and fetus

Cigarette smoking during pregnancy is associated with potentially harmful changes in both maternal and fetal thyroid function, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism ( JCEM ).

14 Jan 2009

Fruits, vegetables and fiber may cut risk of breast cancer recurrence in women without hot flashes

A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors - women who didn't have hot flashes - by approximately 31 percent.

15 Dec 2008

New research provides a clinical picture of obstructive sleep apnea from over six million hospital admissions

Research in the current issue of the Journal of Clinical Sleep Medicine is the first to show the full clinical picture of comorbid conditions associated with obstructive sleep apnea (OSA), quantify their frequency of occurrence and reveal their possible interrelationships.

15 Dec 2008

Tau protein expression predicts breast cancer survival in an unexpected way

Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center.

14 Dec 2008

Aromatase inhibitors most effective in preventing breast cancer from coming back

Two separate meta-analyses of clinical trials from around the world that tested tamoxifen against aromatase inhibitor drugs in postmenopausal women with early breast cancer have each reached the same conclusion: aromatase inhibitors are more effective in preventing breast cancer from coming back.

12 Dec 2008

Childhood obesity may change thyroid

In addition to its strong associations with hypertension, cardiovascular disease, and diabetes, pediatric obesity may induce alterations in thyroid function and structure, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

3 Dec 2008

Broccoli compound, indole-3-carbinol targets key enzyme in late-stage cancer

An anti-cancer compound found in broccoli and cabbage works by lowering the activity of an enzyme associated with rapidly advancing breast cancer, according to a University of California, Berkeley, study appearing this week in the online early edition of the journal Proceedings of the National Academy of Sciences.

3 Dec 2008

More alkaline diet strengthens skeletal health

Diets that are high in protein and cereal grains produce an excess of acid in the body which may increase calcium excretion and weaken bones, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Dec 2008

A potential new procedure for treating obesity

Lining the upper portion of the small intestine with an impermeable sleeve led to both weight loss and restoration of normal glucose metabolism in an animal model of obesity-induced diabetes.

24 Nov 2008

Endocrine News and Research

Breakthrough in thyroid cancer may enable more targeted risk assessment and earlier intervention

Study tests salsalate anti-inflammatory for poorly controlled type 2 diabetes

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Vitamin D related to muscle power, force, velocity and jump height in adolescent girls

Growth hormone treatment for six months after weight loss surgery prevents loss of muscle mass

Hormone level during pregnancy may identify women at risk for postpartum depression

Bioidentical hormone facts and perspectives

Bipolar disorders linked to increased risk of early death from medical illness

Short intense exercise best way to lower risk of diabetes

Osteoporosis? Look out for depression

Prenatal exposure to environmental pollutants linked to higher BMI in toddlers

Smoking during pregnancy impacts thyroid function of mother and fetus

Fruits, vegetables and fiber may cut risk of breast cancer recurrence in women without hot flashes

New research provides a clinical picture of obstructive sleep apnea from over six million hospital admissions

Tau protein expression predicts breast cancer survival in an unexpected way

Aromatase inhibitors most effective in preventing breast cancer from coming back

Childhood obesity may change thyroid

Broccoli compound, indole-3-carbinol targets key enzyme in late-stage cancer

More alkaline diet strengthens skeletal health

A potential new procedure for treating obesity

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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