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New treatment approach shows promise in reversing hormone resistance in breast cancer

A collaborative study between LSU Health New Orleans School of Medicine, the University of Rochester and Cellestia Biotech AG, a biopharmaceutical company headquartered in Basel, Switzerland, provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively.

9 Aug 2023

High-level BPA exposure may affect male fertility

Scientists discuss the effect of bisphenol A on human male fertility.

9 Aug 2023

Link found between vitamin D deficiency and metabolic abnormalities in children: New insights unveiled

Researchers investigated the correlation between vitamin D deficiency and metabolic syndrome (MetS) components.

8 Aug 2023

NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.

7 Aug 2023

Maintaining the health of the gut microbiome by a new peptide

Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago.

4 Aug 2023

Research sheds light on the causes of endometriosis-related pelvic pain

Pelvic pain in women with endometriosis is attributed to neuroinflammation. Researchers investigated biochemical mediators of endometriosis-associated pelvic pain to provide a foundation to identify new drugs to improve symptoms and quality of life.

3 Aug 2023

Precocious puberty on the rise in girls during COVID-19 pandemic

The number of girls diagnosed with precocious puberty increased during the COVID-19 pandemic due to potential risk factors such as increased screen time and less physical activity, according to a new study published in the Journal of the Endocrine Society.

3 Aug 2023

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Researchers examined current evidence on the reasons and implications of pancreatic beta-cell failure.

3 Aug 2023

UCSF Medical Center named to Honor Roll of nation's top hospitals

U.S. News & World Report ranks UCSF Health adult care among nation's top 10 hospitals in 7 specialties, Best in the West for neurology/neurosurgery and rheumatology.

1 Aug 2023

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

The effects of oxidative stress on women’s fertility

Scientists review existing literature to assess the relationship between oxidative stress and female infertility.

1 Aug 2023

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).

1 Aug 2023

Black women weigh emerging risks of ‘creamy crack’ hair straighteners

Deanna Denham Hughes was stunned when she was diagnosed with ovarian cancer last year. She was only 32. She had no family history of cancer, and tests found no genetic link. Hughes wondered why she, an otherwise healthy Black mother of two, would develop a malignancy known as a "silent killer."

1 Aug 2023

Cadmium exposure disrupts placental hormones, harming fetal development

As with many toxins, exposure to the toxic metal cadmium during pregnancy can adversely impact fetal development.

28 Jul 2023

Older sexual and gender minority adults have higher rates of frailty, study shows

In June, the U.S. Census Bureau announced that the average age of the U.S. population reached a new high of nearly 39 years old.

25 Jul 2023

Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome

Researchers utilize bibliometric analysis to investigate the relationship between the gut microbiome and Alzheimer's disease pathogenesis.

25 Jul 2023

Generating functional parathyroid glands from mouse embryonic stem cells

Regenerative medicine has opened up exciting possibilities in the world of medicine. Now, researchers in Japan are searching for ways to recreate and rebuild body tissues and organs, which may be an alternative cure for diseases.

24 Jul 2023

Proposed Labor-HHS funding bill could put endocrine research, disease prevention, and treatment at risk

The Endocrine Society opposes severe funding cuts proposed in the House Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS) funding bill that would put life-saving endocrine research, disease prevention, and treatment at risk.

21 Jul 2023

Epigenetic formatting of satiety gene may increase risk of obesity in women

What determines whether we become overweight? Aside from lifestyle, predisposition plays a role, but genes cannot fully explain the inherited propensity to accumulate excess weight.

19 Jul 2023

Breast cancer treatment linked to faster biological aging

Women diagnosed and treated for breast cancer have increased biological aging compared to women who remain free of breast cancer, according to a new study by researchers at the National Institutes of Health and their collaborators.

19 Jul 2023

Endocrine News and Research

New treatment approach shows promise in reversing hormone resistance in breast cancer

High-level BPA exposure may affect male fertility

Link found between vitamin D deficiency and metabolic abnormalities in children: New insights unveiled

NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

Maintaining the health of the gut microbiome by a new peptide

Research sheds light on the causes of endometriosis-related pelvic pain

Precocious puberty on the rise in girls during COVID-19 pandemic

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

UCSF Medical Center named to Honor Roll of nation's top hospitals

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

The effects of oxidative stress on women’s fertility

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

Black women weigh emerging risks of ‘creamy crack’ hair straighteners

Cadmium exposure disrupts placental hormones, harming fetal development

Older sexual and gender minority adults have higher rates of frailty, study shows

Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome

Generating functional parathyroid glands from mouse embryonic stem cells

Proposed Labor-HHS funding bill could put endocrine research, disease prevention, and treatment at risk

Epigenetic formatting of satiety gene may increase risk of obesity in women

Breast cancer treatment linked to faster biological aging

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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