Endoplasmic reticulum (ER) News and Research

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Take Care Health Systems now offering nebulizer treatments for acute respiratory distress

Take Care Health Systems is now offering nebulizer treatments, when clinically appropriate, for clinic patients exhibiting acute respiratory distress.

6 Aug 2009

Discovery of new gene mutations linked to leukemia

Decoding the complete DNA of cancer patients is giving scientists at Washington University School of Medicine in St. Louis a clearer picture of the complexity of the disease and allowing them to see intriguing and unexpected genetic relationships among patients.

5 Aug 2009

Impax Labs receives FDA approval for generic version of Depakote

Impax Laboratories has confirmed that the U.S. Food and Drug Administration (FDA) has granted final approval of the Company’s Abbreviated New Drug Application (ANDA) for generic version of Depakote® (divalproex ER) 500mg Extended-release Tablets.

5 Aug 2009

Emergency physicians should trust their judgment on chest pain symptoms

Their research suggests that emergency physicians should counsel with other physicians against discharge when they feel strongly about a patient for whom there is no compelling data, other than our evaluation and judgment, Chandra said.

4 Aug 2009

Uninsured account for 20% of U.S. ER visits

Health and Human Services Secretary Kathleen Sebelius today released new data from the Nationwide Emergency Department Sample -- the largest, all-payer emergency department database in the United States.

15 Jul 2009

Research shows how obesity sets the stage for diabetes

Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two.

22 Jun 2009

Discovery of four new breast cancer targets

Four suspects often found at the scene of the crime in cancer are guilty of the initiation and progression of breast cancer in mice that are resistant to the disease, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the June edition of Cancer Cell.

10 Jun 2009

Research questions standard protocol for treating traumatic brain injury

Traumatic brain injury - not heart disease, stroke or cancer - is the number one cause of death and disability in people under 45. Each year, some 1.5 million Americans, including soldiers, athletes, the elderly and children, sustain head injuries, and nearly half of them will be hospitalized and treated in an emergency room or intensive care unit.

3 Jun 2009

Protein discovery provides new targets for drugs that could extend the healthy years of life

A protein that plays a key role in tumor formation, oxygen metabolism and inflammation is involved in a pathway that extends lifespan by dietary restriction.

22 May 2009

Genetic signature predicts clinical outcomes in certain types of breast cancer

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.

19 May 2009

Urgent Care Centers: Between the ER and the family doctor

Urgent care centers (UCCs) are providing an alternative to emergency room treatment. A study published in the open access journal BMC Health Services Research has shown that UCCs tend to be open well outside of office hours and offer a wider range of services than primary care offices.

14 May 2009

San Francisco Chronicle examines emergency department HIV testing program

The San Francisco Chronicle on Monday examined an HIV testing program at San Francisco General Hospital's emergency department, which is part of a nationwide CDC program that offers routine testing to all ED patients.

12 May 2009

Loss of stromal protein major new prognostic factor in patients with breast cancer

Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, predicting early disease recurrence, metastasis and breast cancer patient survival.

6 May 2009

Drugs designed to tackle endoplasmic reticulum stress might be useful in treating heart disease

Researchers say they have evidence to explain what separates your average blood vessel plaque from those that are at high risk for triggering the development of dangerous - even fatal - blood clots.

5 May 2009

Level of cellular stress determines longevity of retinal cells

Stress can be adaptive. It can make you sharper, help you focus and it can even improve your performance. But too much of it can tax cells to the point where they can no longer cope and slowly self-destruct.

30 Apr 2009

New York Times examines use of message placement on TV programs

The Bill & Melinda Gates Foundation is "set to expand its involvement" with the entertainment industry and "spend more money on influencing popular culture" through a new deal with Viacom, the parent company to television networks that include MTV, VH1, Nickelodeon and BET, the New York Times reports.

5 Apr 2009

Statins reduce odds of an asthma-related hospitalization or ER visit

Results of a new study presented at the 2009 Annual Meeting of the American Academy of Asthma, Allergy and Immunology (AAAAI) show dramatic reductions in emergency room (ER) visits and hospitalizations for asthma patients taking cholesterol-lowering statins in addition to common asthma treatments.

15 Mar 2009

Racial disparities in ER length of stay point to added risks for minority patients

Sick or injured African-American patients wait about an hour longer than patients of other races before being transferred to an inpatient hospital bed following emergency room visits, according to a new national study published in the journal Academic Emergency Medicine.

5 Mar 2009

Discovery of new gene that causes Leber congenital amaurosis and retinitis pigmentosa

The team of Dr. Robert Koenekoop which includes Dr. Irma Lopez from the Research Institute of the MUHC at the Montreal Children's Hospital played a crucial role in the international collaboration that led to the discovery of a new gene that causes Leber congenital amaurosis (LCA) and retinitis pigmentosa (RP), two devastating forms of childhood blindness.

5 Mar 2009

Incidental findings during trauma evaluation - a growing concern

Nearly one-fifth of trauma patients who undergo CT evaluation have incidental findings, according to a study performed by Columbus Radiology Corp. at Grant Medical Center in Columbus, OH.

4 Mar 2009