Endoplasmic reticulum (ER) News and Research

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Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

SARS-CoV-2 infection regulates protein arginylation

SARS-CoV-2 infection regulates protein arginylation

Adaptive immunity in patients infected with SARS-CoV-2 Δ382 Variant

Adaptive immunity in patients infected with SARS-CoV-2 Δ382 Variant

Cancer cells exploit genetic and cellular processes to promote tumor growth

Cancer cells exploit genetic and cellular processes to promote tumor growth

Study identifies how cancer cells transform macrophages into supporters of their growth

Study identifies how cancer cells transform macrophages into supporters of their growth

Role of S-acylation in SARS-CoV-2 infectivity

Role of S-acylation in SARS-CoV-2 infectivity

Study reveals why SARS-CoV-2 is more infectious than SARS-CoV-1

Study reveals why SARS-CoV-2 is more infectious than SARS-CoV-1

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

Scientists uncover the early assembly of gamma-secretase involved in plaque production

Scientists uncover the early assembly of gamma-secretase involved in plaque production

Thiol-based mucolytics show potent allosteric inhibition of SARS-CoV-2-ACE2 binding via disulfide reduction

Thiol-based mucolytics show potent allosteric inhibition of SARS-CoV-2-ACE2 binding via disulfide reduction

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Researchers develop new imaging technique for studying nanoscale coronavirus-host interactions

Researchers develop new imaging technique for studying nanoscale coronavirus-host interactions

Melatonin prevents kidney damage caused by metabolic complications of obesity

Melatonin prevents kidney damage caused by metabolic complications of obesity

Could GRP78 be a therapeutic target against COVID-19?

Could GRP78 be a therapeutic target against COVID-19?

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell