Endoplasmic reticulum (ER) News and Research

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Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

For many years, the answer to that question was unequivocally "No." But as the University of Utah School of Medicine's annual Utah Cardiac Recovery Symposium will explore on Jan. 12-13, advances in treating heart failure are giving physicians, surgeons and researchers reason to hope the deadly disease might one day be defeated.

6 Jan 2017

Indoor smoking bans reduce asthma-related ER visits among children

Emergency rooms in communities with indoor smoking bans reported a 17 percent decrease in the number of children needing care for asthma attacks, according to new research from the University of Chicago Medicine.

30 Dec 2016

New study reveals IRBIT's role in facilitating apoptosis

Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur properly.

21 Dec 2016

‘Watershed in metabolon research’ unlocks plants' secret medicinal toolbox

Metabolons, near-mythical clusters of enzymes, have been discovered for the first time. Using fluorescent tags and microscopy -- molecular movie technology - scientists have confirmed their existence, thus unlocking plants' secret medicinal toolbox.

21 Dec 2016

Anticholinergic drugs linked to increased rate of emergency department and hospital visits

Anticholinergic medications, a class of drugs very commonly used by older adults, are linked to an increased rate of emergency department and hospital utilization in the United States, according to an Indiana University Center for Aging Research, Indiana University Center for Health Innovation and Implementation Science, and Regenstrief Institute study of community-dwelling Americans age 65 and older.

21 Dec 2016

Protective effect of ER-beta more pronounced in breast cancer patients who undergo chemotherapy

It is known from previous research that the ER-beta estrogen receptor often has a protective effect. A new study from Lund University in Sweden has found that this effect is more pronounced in patients that undergo chemotherapy.

15 Dec 2016

UNIST study could open up new avenues of research in cancer treatment

The new study, by researchers from UNIST demonstrates a more holistic light-based treatment to nuke cancer cells instead of surgery. The results, reported in the September issue of the Journal of the American Chemical Society, could open up new avenues of research in cancer treatment.

14 Dec 2016

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

Around 20% of breast cancer patients do not complete prescribed endocrine therapy, researchers report at the ESMO Asia 2016 Congress in Singapore.1 The study in over 5,500 women found that younger patients and those who had taken hormone replacement therapy (HRT) were less likely to adhere to their medicine.

14 Dec 2016

Duke researchers develop new cell-based drug screening test for dystonia

Duke University researchers have identified a common mechanism underlying separate forms of dystonia, a family of brain disorders that cause involuntary, debilitating and often painful movements, including twists and turns of different parts of the body.

8 Dec 2016

TMDU researchers identify novel type of cell death in Huntington's disease

In Huntington's disease (HD), the huntingtin gene is mutated, causing progressive neuronal death.

22 Nov 2016

New survey finds 1 in 4 vacations includes visit to ER

If you've ever had to seek medical attention for an illness or an injury during a vacation, you're not alone.

21 Nov 2016

Researchers need to know more about proinsulin misfolding to better understand diabetes

According to the World Health Organization, 422 million adults across the globe have diabetes. In fact, the number of adults with the disease continues to grow each year.

17 Nov 2016

Retail clinics do not reduce emergency department visits, study finds

Despite being touted as a way to reduce emergency department visits, retail clinics opened near emergency departments had little effect on rates of low-acuity visits to them, according to the results of a study published online today in Annals of Emergency Medicine ("Association Between the Opening of Retail Clinics and Low-Acuity Emergency Department Visits").

14 Nov 2016

Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Amyotrophic lateral sclerosis (ALS) is an adult onset, fetal neurodegenerative disease that selectively affects motor neurons.

8 Nov 2016

New study shows final stages of how mitochondria regularly divide and propagate

A new University of Colorado Boulder study shows for the first time the final stages of how mitochondria, the sausage-shaped, power-generating organelles found in nearly all living cells, regularly divide and propagate.

2 Nov 2016

Study explores cost-effectiveness of school-based dental sealant programs for children

New research findings demonstrate that school-based dental sealant programs, in which students receive preventative oral care while at school, are cost-effective in protecting at-risk children's permanent teeth from decay.

27 Oct 2016

Study identifies factors that increase risk for breast cancer in young African American women

Black women under the age of 45 are at increased risk for an aggressive form of breast cancer [estrogen receptor (ER) negative] if they experienced a high number of pregnancies, never breast fed, and/or had higher waist-to-hip ratio.

19 Oct 2016

Activation of chemical with ER-β may help reduce obesity by converting white fat to brown fat

New research, published online in The FASEB Journal, suggests that activation of a chemical called Beta-LGND2 by the estrogen receptor Beta (ER-Beta) reduces obesity and metabolic diseases in mice by converting bad fat (white fat) to good fat (brown fat).

17 Oct 2016

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Fulvestrant significantly increases progression-free survival in women with hormone-receptor-positive advanced breast cancer, particularly those with less aggressive lower-volume disease, researchers reported at the ESMO 2016 Congress in Copenhagen

8 Oct 2016

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

A supplemental "boost" of radiation improves local control and provides an incremental benefit in decreasing breast cancer recurrence for patients with Ductal Carcinoma In Situ (DCIS) who receive whole breast radiation therapy radiation (WBRT) following lumpectomy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

27 Sep 2016

Endoplasmic reticulum (ER) News and Research

Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

Indoor smoking bans reduce asthma-related ER visits among children

New study reveals IRBIT's role in facilitating apoptosis

‘Watershed in metabolon research’ unlocks plants' secret medicinal toolbox

Anticholinergic drugs linked to increased rate of emergency department and hospital visits

Protective effect of ER-beta more pronounced in breast cancer patients who undergo chemotherapy

UNIST study could open up new avenues of research in cancer treatment

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

Duke researchers develop new cell-based drug screening test for dystonia

TMDU researchers identify novel type of cell death in Huntington's disease

New survey finds 1 in 4 vacations includes visit to ER

Researchers need to know more about proinsulin misfolding to better understand diabetes

Retail clinics do not reduce emergency department visits, study finds

Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

New study shows final stages of how mitochondria regularly divide and propagate

Study explores cost-effectiveness of school-based dental sealant programs for children

Study identifies factors that increase risk for breast cancer in young African American women

Activation of chemical with ER-β may help reduce obesity by converting white fat to brown fat

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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