Endoplasmic reticulum (ER) News and Research

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Scientists have, for the first time, induced a state of reversible metabolic hibernation in mice

Scientists at Fred Hutchinson Cancer Research Center have, for the first time, induced a state of reversible metabolic hibernation in mice. This achievement, the first demonstration of "hibernation on demand" in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues.

23 Apr 2005

To boost efficiency, hospitals borrow principles from factory floor

Many health-care industry bottlenecks can be eliminated, resulting in major improvements in efficiency, cost savings and patient care when hospitals borrow principles from production lines on the factory floor, according to researchers in the School of Engineering and Applied Sciences at the University at Buffalo.

13 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Relief for overactive bladder patients

New landmark data (the STAR Study), revealed today from the European Association of Urology in Istanbul, Turkey, show that patients suffering from Overactive Bladder (OAB) syndrome will see considerably better improvements in their symptoms when being treated with the new antimuscarinic drug solifenacin, than on tolterodine ER - an antimuscarinic drug that is widely used.

17 Mar 2005

New twist on the role that estrogens play in the development of behavioral differences between men and women

What makes a man behave like a man and a woman a woman? The answer may be partly in your genes. Researchers at the University of Virginia Health System have discovered a new twist on the role that estrogens play in the development of behavioral differences between males and females.

14 Mar 2005

Scientists have identified a key network that prevents damage by oxygen radicals

Reactive oxygen species (ROS), or 'oxygen radicals', have been identified as major contributors to signs of premature aging, increased cancer prevalence linked to inflammation-associated syndromes and a variety of human diseases.

6 Mar 2005

Blocking estrogen may be vitally important to improving survival from lung cancer

New and effective treatments for lung cancer may rest on their ability to hinder the action of estrogen in lung cancer cells, according to two studies published in the current issue of Cancer Research.

15 Feb 2005

Why estrogenic hormones produce unintended results in women

New research is shedding light on why estrogenic hormones produce unintended results in women, giving hope to the idea that new drugs might reach their targets and work more effectively. Ultimately it could mean that postmenopausal women would know that hormone-replacement therapy would have only its intended result.

13 Feb 2005

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine will begin in the Washington, DC area in a couple of months after the U.S. Food and Drug Administration conferred investigational new drug status on the vaccine.

27 Jan 2005

FDA clearance for laser contact bone removal

Lumenis Ltd., and OpusDent Ltd., its dental laser division, announced the FDA clearance of the OpusDuo™ Er:YAG laser system for contact bone removal during oral surgical and periodontal procedures.

From Lumenis Inc. 3 Jan 2005

U.S. patent granted for laser pulse technology

Biolase Technology today announced that it has been granted a new U.S. patent protecting key areas related to its laser pulse technology.

13 Dec 2004

Schwarzenegger puts tens of thousands of Californians at risk, according to Californian Nurses

The California Nurses Association condemned a decision by Gov. Arnold Schwarzenegger today, at the behest of the multi-billion dollar hospital industry, to suspend major provisions of California's law requiring safe registered nurse-to-patient staffing ratios

5 Nov 2004

Gene regulated by need to process proteins linked to enlargement of protein processing factory

Part of a cellular mechanism that regulates the folding of new proteins into their proper shapes also includes a genetic response that enlarges the factory where both protein folding and packaging of proteins occurs.

2 Nov 2004

New way to study individual living bacteria cells and analyze their chemistry

Researchers at the U.S. Department of Energy's Argonne National Laboratory have found a new way to study individual living bacteria cells and analyze their chemistry.

22 Oct 2004

Discovery of fundamental mechanism within cells that link obesity and type 2 diabetes

Researchers from the Harvard School of Public Health have discovered what they believe is the fundamental mechanism within cells that links two fast-rising public health threats: obesity and Type 2 diabetes.

18 Oct 2004

Disruption of protein folding causes neurodegeneration, mental retardation

Excess accumulation in brain cells of a fat molecule called GM1-ganglioside (GM1) disrupts the folding of newly assembled proteins into their proper shapes, triggering nerve degeneration and mental retardation in children.

10 Sep 2004

Study is the first comprehensive risk analysis to examine both the risk of death from breast cancer and other causes following diagnosis

Women who are diagnosed with breast cancer at a young age, or at an advanced stage at any age, are more likely to die from the disease than from all other causes of death combined, according to a new study by scientists at the National Cancer Institute.

1 Sep 2004