Endothelial cell News and Research

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Abdominal fat, not BMI, may help better predict risk for coronary artery disease

For years, women have been told that weight gain could lead to heart disease. A new study indicates that it is the location of the fat that matters most, with abdominal fat representing the greatest harm and not overall body mass index when assessing risk for coronary artery disease.

28 Aug 2019

New cellular processes controlling the formation of lymphatic valves found

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms or legs.

28 Aug 2019

NUS scientists discover control mechanism that regulates traffic across blood vessels

NUS scientists have discovered a control mechanism that regulates the traffic of cells and substances across blood vessels. This effect can have significant impact on cancer metastasis.

13 Aug 2019

Novel dual approach can be a promising way to enhance cardiac repair

As a medical emergency caused by severe cardiovascular diseases, myocardial infarction (MI) can inflict permanent and life-threatening damage to the heart.

12 Aug 2019

Vitamin D is essential for preventing preeclampsia

A new study suggests vitamin D may reverse impaired cell interactions in the blood vessels that occur in preeclampsia- a pregnancy complication characterized by high blood pressure.

9 Jul 2019

Stem cell study reveals the harmful effects of flavored e-cigarette liquids

Your favorite vape flavor may be more harmful than the nicotine itself. Using stem cells to investigate the impact of e-liquids on cardiovascular disease, a new study has revealed the harmful effects of flavored e-cigarette liquids and e-cigarette use.

28 May 2019

Acute exposure to flavored e-liquids exacerbates endothelial cell dysfunction, study finds

There has been a rapid rise in e-cigarette use, but its health effects have not been well-studied and their effect on vascular health remains unknown.

28 May 2019

WFIRM researchers engineer vascularized functional renal tissues for kidney regeneration

Wake Forest Institute for Regenerative Medicine researchers have shown the feasibility of bioengineering vascularized functional renal tissues for kidney regeneration, developing a partial augmentation strategy that may be a more feasible and practical approach than creating whole organs.

24 May 2019

Researchers develop new molecule that binds to the cerebrovascular system

Brazilian and US researchers have developed a molecule called FRW that, in tests with mice, proved capable of binding to blood vessels in the brain but not in other organs when injected into the bloodstream.

7 May 2019

Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death

Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet in Munich team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death and that a tailored peptide inhibits the process.

2 May 2019

Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia

Most patients with chronic myelogenous leukemia can be treated with tyrosine kinase inhibitors. These drugs are highly effective and lead to deep remission and prolonged survival.

22 Mar 2019

Researchers create 3D vascularized proximal tubule model to study renal reabsorption

Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt and excess fluid from building up inside our bodies.

5 Mar 2019

Study reveals potential pathway for endothelial cells to avoid apoptosis

Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth.

17 Jan 2019

Study explains effects of aging on endothelial health and vascular regenerative capacity

The endothelium plays an important role in cardiovascular regulation, from blood flow to platelet aggregation, immune cell infiltration and demargination.

28 Dec 2018

Improving blood vessel growth could help mitigate health problems arising from obesity

New research led by York University's Faculty of Health shows that inhibiting a protein within blood vessels stimulates new blood vessel growth, resulting in healthier fat tissue and lower blood sugar levels.

5 Dec 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

University of Houston biologist Michihisa Umetani, having discovered that a certain protein partnership acts to rapidly signal molecules inside blood vessels that danger is upon them, has been awarded $382,500 by the National Institutes of Health.

10 Oct 2018

Bioaxone Biosciences receives Fast-Track SBIR grant to assess potential of Rho Kinase 2 inhibitor

BioAxone BioSciences, Inc. announced today the receipt of a Fast-Track grant from the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, as part of the agency's Small Business Innovation Research Program.

27 Sep 2018

Research team to investigate how blood flow influences formation of plaque

Atherosclerosis-;the narrowing of arteries due to plaque buildup-;is the underlying reason for the majority of strokes and heart attacks. When atherosclerosis occurs in the arteries that carry blood to the heart muscle, it is called coronary artery disease, the No. 1 killer of Americans.

30 Aug 2018

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

XBiotech Inc. announced today the publication of findings that point toward a white blood cell-derived interleukin-1 alpha (IL-1⍺) as a cause of blood clots that could lead to heart attacks or strokes.

28 Aug 2018