Endothelin News and Research

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Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.
Olive oil supplements may counteract adverse cardiovascular effects of air pollution

Olive oil supplements may counteract adverse cardiovascular effects of air pollution

Ambrisentan cleared for use with phenprocoumon

Ambrisentan cleared for use with phenprocoumon

Meta-analysis links signalling pathways to bipolar disorder

Meta-analysis links signalling pathways to bipolar disorder

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Bayer’s Adempas now available in the UK to treat patients with CTEPH

ATS develops clinical practice guidelines to help clinicians identify, manage patients with sickle cell disease

ATS develops clinical practice guidelines to help clinicians identify, manage patients with sickle cell disease

New research uncovers abnormal molecular signaling pathways for kidney failure

New research uncovers abnormal molecular signaling pathways for kidney failure

Researchers identify protein that promotes growth of brain cells damaged by MS

Researchers identify protein that promotes growth of brain cells damaged by MS

Novel IRL-1620 compound may be useful in treating Alzheimer's disease

Novel IRL-1620 compound may be useful in treating Alzheimer's disease

Opsumit drug receives FDA approval to treat adults with pulmonary arterial hypertension

Opsumit drug receives FDA approval to treat adults with pulmonary arterial hypertension

Bayer HealthCare receives FDA approval for Adempas tablets

Bayer HealthCare receives FDA approval for Adempas tablets

Intracerebral injection of BSC may reduce post-stroke cognitive dysfunction

Intracerebral injection of BSC may reduce post-stroke cognitive dysfunction

BSCs may offer new approach for reducing post-stroke cognitive dysfunction

BSCs may offer new approach for reducing post-stroke cognitive dysfunction

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

Study promises effective treatment for stroke patients

Study promises effective treatment for stroke patients

Sildenafil does not improve exercise capacity in HF patients with preserved ejection fraction

Sildenafil does not improve exercise capacity in HF patients with preserved ejection fraction

Medications often prescribed for PAH could affect heart health of treated patients

Medications often prescribed for PAH could affect heart health of treated patients

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Bayer announces data from riociguat Phase III trial on CTEPH

Bayer announces data from riociguat Phase III trial on CTEPH

Bayer announces data from riociguat Phase III pulmonary arterial hypertension trial

Bayer announces data from riociguat Phase III pulmonary arterial hypertension trial

Health Canada approves XIAFLEX for Dupuytren's contracture

Health Canada approves XIAFLEX for Dupuytren's contracture