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MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Natural compound activates macrophages to fight resistant tuberculosis bacteria

Tuberculosis (TB) is a prevalent infectious disease that affects millions of people each year. It was previously the leading cause of death from a single pathogen before the COVID-19 pandemic.

11 Dec 2023

Researchers produce artificial cells with potential for drug delivery and tissue engineering

Artificial cells, made with the use of synthetic materials, have been produced in international research led at the University of Strathclyde.

11 Dec 2023

Expanding the toolbox for drug design: New enzymes for tailoring molecules

Simon Schröder has worked out how enzymes can be used to more easily form the desired bond between two nitrogen atoms.

8 Dec 2023

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Viruses have limited genetic material-;and few proteins-;so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.

8 Dec 2023

New discovery could provide a potential target to treat diabetes

Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body-;a discovery that could provide a new target to treat diabetes.

8 Dec 2023

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Study examines the efficacy of anastrozole in preventing breast cancer in postmenopausal women at high risk, focusing on the role of baseline estradiol levels and their impact on treatment outcomes.

7 Dec 2023

Novel mechanism leads to motor neuron degeneration in spinal muscular atrophy

The lab of Yongchao C. Ma, PhD, at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago uncovered a novel mechanism that leads to motor neuron degeneration in spinal muscular atrophy (SMA).

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Peer-reviewed study published in Xenobiotica describes an innovative new method that predicts the routes and products of Phase I and II metabolism with high sensitivity and greater precision than other approaches.

From Optibrium Ltd. 7 Dec 2023

Arxspan BioDrive: A Versatile Solution for Molecular Biology

In this interview, NewsMedical speaks to Arxspan about its new all-in-one solution for molecular biology.

From Arxspan 5 Dec 2023

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

The safety, efficacy, and immunogenicity of a mRNA-based vaccine.

5 Dec 2023

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

A group of authors critically evaluated and interpreted the evidence linking mitochondrial dysfunction and metabolic changes to the pathogenesis of Alzheimer's disease (AD).

5 Dec 2023

Omicron infection linked to brain structure changes in men, study finds

Study reveals that men infected with the SARS-CoV-2 Omicron variant experience changes in brain structure, including reduced gray matter thickness and subcortical nuclear volume. These findings, based on MRI data and clinical symptoms, highlight the neurological impact of Omicron infection, contributing to our understanding of COVID-19's effects on the brain.

4 Dec 2023

Study reveals G6PD deficiency linked to higher ADHD risk and increased use of stimulant medications

The risk of Attention Deficit/Hyperactivity Disorder (ADHD) among glucose 6-phosphate dehydrogenase (G6PD)-deficient individuals.

1 Dec 2023

Study reveals differences in SARS-CoV-2 entry mechanisms between humans and mink

Some viruses move between species. For example, SARS-CoV-2, the virus that causes COVID-19, can spill over from humans to mink, an agricultural species, and then spill back from mink to humans.

29 Nov 2023

Unveiling a new cardiac myosin inhibitor through AI-driven virtual screening

Discovery of a novel cardiac-specific myosin modulator.

28 Nov 2023

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Researchers used a Mendelian randomization approach to conduct a genetic association analysis of the levels of over 3,000 proteins to identify biomarkers for early breast cancer detection.

28 Nov 2023

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Two kiwi fruit every day safe and can replace vitamin C supplementation

Study investigates the health effects of consuming two kiwifruits daily for six weeks. It finds no significant changes in metabolic and inflammatory biomarkers, indicating that regular kiwifruit consumption is safe and increases dietary vitamin C intake without adversely affecting metabolic health.

27 Nov 2023

Enzyme News and Research

MIT scientists develop nanoparticles to reduce inflammation in the brain

Natural compound activates macrophages to fight resistant tuberculosis bacteria

Researchers produce artificial cells with potential for drug delivery and tissue engineering

Expanding the toolbox for drug design: New enzymes for tailoring molecules

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

New discovery could provide a potential target to treat diabetes

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Novel mechanism leads to motor neuron degeneration in spinal muscular atrophy

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Arxspan BioDrive: A Versatile Solution for Molecular Biology

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

Omicron infection linked to brain structure changes in men, study finds

Study reveals G6PD deficiency linked to higher ADHD risk and increased use of stimulant medications

Study reveals differences in SARS-CoV-2 entry mechanisms between humans and mink

Unveiling a new cardiac myosin inhibitor through AI-driven virtual screening

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Two kiwi fruit every day safe and can replace vitamin C supplementation

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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