Enzyme News and Research

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Molecular biologists find chink in the armor of Candida, the most common human fungal pathogen

Molecular biologists at Rice University have discovered a key defense mechanism that the yeast Candida albicans uses against attack by the human immune system.

26 Jun 2004

Genetic variation that doubles the risk for rheumatoid arthritis

A team of researchers has discovered a genetic variation that doubles the risk for rheumatoid arthritis (RA).

24 Jun 2004

Class of molecules that could lead to treatments for a wide range of diseases, including cancer, arthritis, and heart disease

By making use of model compounds in drug design, chemists at the University of California, San Diego identified a class of molecules that could lead to treatments for a wide range of diseases, including cancer, arthritis, and heart disease.

21 Jun 2004

New gene found in genetic wasteland

In a region of DNA long considered a genetic wasteland, Harvard Medical School researchers have discovered a new class of gene.

20 Jun 2004

A natural molecule that blocks a key bacterial enzymes could lead to a new generation of antibiotics

Rutgers scientists have deciphered the complex mechanics of microcin J25 (MccJ25), a tiny, natural molecule that acts like a cork in a bottle to block a key bacterial enzyme – potentially leading to a new generation of antibiotics.

17 Jun 2004

Xenobiotic gets patent approval for toxin detection

XDS consultant (and former XDS laboratory director) Michael Chu and President George Clark combined their research skills to develop a rapid and relatively inexpensive methodology to quantify TEQs (Toxic Equivalence -- measures of toxicity adopted by the World Health Organization) for individual toxic chemical groups.

17 Jun 2004

Heart attack patients are discharged without evidenced-based, guideline recommended, life-prolonging therapies

Heart attack care is more likely to match recommended guidelines when health care providers use standardized forms and other reminders, and institutional systems reinforce goals for treatment and patient lifestyles, according to a new study in the June 16, 2004 issue of the Journal of the American College of Cardiology.

16 Jun 2004

Size and shape of synapses among neurons in the cerebral cortex determine long term memory capability

In a study to appear in the June 10 issue of Neuron, neuroscientists at the Picower Center for Learning and Memory at MIT show for the first time that storage of long-term memories depends on the size and shape of synapses among neurons in the outer part of the brain, the cerebral cortex.

14 Jun 2004

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population. In a new study, scientists may have found a culprit: a serious deficiency of nitric oxide, a small molecule vital in the regulation of blood flow and blood pressure.

11 Jun 2004

New treatment significantly improves long-term outlook for breast cancer survivors

An updated analysis from an international clinical trial of the drug letrozole was presented on June 8, 2004 at the American Society of Clinical Oncology annual meeting in New Orleans.

11 Jun 2004

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

A study by researchers at Cornell University suggests that higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes.

10 Jun 2004

Non-aspirin pain drugs may help men with recurrent prostate cancer

Early results from a University of North Carolina at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of non-aspirin pain medicine now widely prescribed for arthritis symptoms, may benefit men with recurrent prostate cancer.

10 Jun 2004

Russian doctors appreciate benefits of natural remedies

"It would appear that American doctors have a long way to go compared to Russian doctors who are, after recognizing the limited results with traditional drugs, are now successfully testing natural remedies," according to nutritional researcher Peter Gillham.

10 Jun 2004

Patent issued for GHB, date rape drug test

A patent for a highly sensitive test to detect the presence of the "date rape" drug, GHB, has recently been granted to the University of California, Santa Barbara.

9 Jun 2004

SU11248 proves effective in the treatment of gastrointestinal stromal tumors

A drug originally developed to block the formation of blood vessels in tumors has been shown to overcome resistance to treatment with Gleevec in patients with gastrointestinal stromal tumors (GIST).

9 Jun 2004

Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Researchers from the Johns Hopkins Kimmel Cancer Center, Indiana University and the University of Michigan have found that some women have a gene mutation that may decrease the effectiveness of tamoxifen, a commonly used breast cancer drug.

7 Jun 2004

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Research presented today showed that the investigational drug, LAF237, the first in a new class, improved glycemic control in patients with type 2 diabetes. In this study, LAF237, which is administered as a tablet to be taken orally, was added to the standard diabetes treatment metformin in patients whose diabetes was not adequately controlled by metformin alone.

7 Jun 2004

Research may help treat muscular dystrophies and other muscle diseases caused by glycosylation defects

Expressing high levels of a sugar-adding protein known as LARGE in mice that lack the protein can prevent muscular dystrophy in these animals, according to studies by researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.

7 Jun 2004

New way to identify cell growth

In a discovery that has relevance in a variety of fields, including human health, UC Riverside Assistant Professor of Biochemistry Frank Sauer and colleagues at UC Riverside, in Germany, and in Wisconsin, have found a new way to identify when a living cell begins to grow.

5 Jun 2004

New way to identify when a living cell begins to grow

3 Jun 2004

Enzyme News and Research

Molecular biologists find chink in the armor of Candida, the most common human fungal pathogen

Genetic variation that doubles the risk for rheumatoid arthritis

Class of molecules that could lead to treatments for a wide range of diseases, including cancer, arthritis, and heart disease

New gene found in genetic wasteland

A natural molecule that blocks a key bacterial enzymes could lead to a new generation of antibiotics

Xenobiotic gets patent approval for toxin detection

Heart attack patients are discharged without evidenced-based, guideline recommended, life-prolonging therapies

Size and shape of synapses among neurons in the cerebral cortex determine long term memory capability

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

New treatment significantly improves long-term outlook for breast cancer survivors

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

Non-aspirin pain drugs may help men with recurrent prostate cancer

Russian doctors appreciate benefits of natural remedies

Patent issued for GHB, date rape drug test

SU11248 proves effective in the treatment of gastrointestinal stromal tumors

Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Research may help treat muscular dystrophies and other muscle diseases caused by glycosylation defects

New way to identify cell growth

New way to identify when a living cell begins to grow

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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