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MicuRx announces initiation of global clinical development program for MRX-I compound

MicuRx Pharmaceuticals, Inc., a privately-held biopharmaceutical company developing next-generation antibiotics, today announced the initiation of a global clinical development program for its lead compound MRX-I, a novel oxazolidinone antibiotic for treatment of Gram-positive infections including methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.

20 Dec 2013

European research project to develop new rapid diagnostic devices

Led by the Basque R&D Alliance IK4, 13 organisations in 8 different countries have been conducting research for three years under the European LabOnFoil project to develop new rapid diagnostic devices.

19 Dec 2013

Researchers discover series of compounds possessing anti-HIV activity

University of Minnesota researchers have discovered a first-of-its-kind series of compounds possessing anti-human immunodeficiency virus (HIV) activity. The compounds present a new target for potential HIV drug development and future treatment options.

18 Dec 2013

E. coli evolution studies may lead to better treatments

Going back in time to compare evolutionary changes in several thousand generations of E. coli, a University of Houston biologist hopes to one day be able to isolate a bacterial pathogen and predict the likelihood it will become resistant to a particular antibiotic.

18 Dec 2013

Researchers discover molecular "switch" in receptor that controls cell behavior

If scientists can control cellular functions such as movement and development, they can cripple cells and pathogens that are causing disease in the body.

17 Dec 2013

Mirimus develops enhanced tools for reversible gene suppression

Over the last decades, RNA interference (RNAi) has become an indispensable tool for functional genetic studies by harnessing the power of a cell intrinsic mechanism enabling reversible gene silencing.

17 Dec 2013

‘Window for intervention’ to forestall hypertensive cognitive decline

Newly diagnosed hypertension is predictive of cognitive decline in middle-aged individuals and is worse in those with poorly controlled blood pressure, Dutch researchers have found.

16 Dec 2013

JHI releases epic3 guidelines on infection prevention for healthcare professionals

The Journal of Hospital Infection has just released the awaited epic3 guidelines on infection prevention and control for a range of healthcare professionals. They are freely available online on ScienceDirect and on the journal's website.

16 Dec 2013

Cancer cells that fuse with macrophages play key role in the spread of cancer

Cancer cells that spontaneously fuse with macrophages, the immune system's healthy scavenger cells, play a key role in the metastasis, or spread of the cancer to other areas of the body, according to research to be presented Sunday, Dec. 15, at the American Society for Cell Biology annual meeting in New Orleans.

16 Dec 2013

Eleven researchers receives 2014 DeLill Nasser Award for Professional Development in Genetics

The Genetics Society of America (GSA) is pleased to announce the selection of eleven early career researchers - five graduate students and six postdoctoral researchers - as recipients of a spring 2014 DeLill Nasser Award for Professional Development in Genetics.

15 Dec 2013

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

New research from University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.

13 Dec 2013

Climate change may lead to decline in snail fever

The dangerous parasite Schistosoma mansoni that causes snail fever in humans could become significantly less common in the future a new international study led by researchers from the University of Copenhagen predicts. The results are surprising because they contradict the general assumption that climate change leads to greater geographical spread of diseases. The explanation is that the parasite's host snails stand to lose suitable habitat due to climate change.

13 Dec 2013

Novel ISM strategy enables selection of potentially effective cancer therapies for patients

A new individualized systems medicine strategy, developed at the Institute for Molecular Medicine Finland FIMM and the Helsinki University Central Hospital, enables a selection of potentially effective cancer therapies for individual patients. The promising results achieved by applying this strategy to chemoresistant adult acute myeloid leukemia patients have been recently published in the Cancer Discovery journal.

13 Dec 2013

JHI released epic3 guidelines on infection prevention and control for range of healthcare professionals

The Journal of Hospital Infection (JHI) has just released the awaited epic3 guidelines on infection prevention and control for a range of healthcare professionals. They are freely available online on ScienceDirect and on the journal's website.

13 Dec 2013

UCSB anthropologists find successful hunting boosts testosterone, cortisol levels in Tsimane men

While small-scale horticulture is a relatively recent addition to the human repertoire of food provisioning, hunting has deep evolutionary roots. In practically every society, hunting ability correlates with reproductive success - the better the hunter, the more children he is likely to father.

13 Dec 2013

MIT assistant professor named Pew biomedical researcher of the month

For his creative work in evolutionary systems biology, Jeff Gore, Ph.D., an assistant professor in physics at Massachusetts Institute of Technology, is The Pew Charitable Trusts' biomedical researcher of the month. Gore is studying how game theory can be applied to bacterial evolution, with the goal of understanding how pathogens become resistant to drugs.

12 Dec 2013

Climate differences drive gene changes, find Virginia Bioinformatics Institute researchers

Interplay between genes and the environment has been pondered at least since the phrase "nature versus nurture" was coined in the mid-1800s.

12 Dec 2013

Cook Medical begins clinical study to evaluate removability of Evolution Esophageal Fully Covered Stent

Cook Medical has initiated a clinical study in the U.S. to evaluate the removability of a new Evolution Esophageal Fully Covered Stent. This is the first multicenter U.S. study to evaluate the possibility of removing a self-expanding metal stent after malignant and benign strictures have been treated. The stent design used in the study has been modified to accommodate retrieval.

12 Dec 2013

New demographic data unveils extraordinary diversity of aging processes

Despite aging being one the hottest topic in the media recently, scientists have no coherent explanation for it. New demographic data on humans, animals and plants for the first time unveil such an extraordinary diversity of aging processes that no existing evolutionary theory can account for. Both life spans and mortalities vary from species to species.

10 Dec 2013

Researchers produce erythrocyte progenitor cells by transducing two genes into iPS and ES cells

By transducing two genes (c-MYC and BCL-XL) into iPS cells and ES cells, a Kyoto University research team led by Prof. Koji Eto at CiRA has succeeded in producing erythrocyte progenitor cells with almost unlimited ability to replicate in vitro, which they then differentiated successfully into mature erythrocytes. Although these erythrocytes consisted mostly of fetal-type hemoglobin, they were confirmed to have oxygen-carrying capacity and to have circulatory capacity following transfusion into mice.

6 Dec 2013

Evolution News and Research

MicuRx announces initiation of global clinical development program for MRX-I compound

European research project to develop new rapid diagnostic devices

Researchers discover series of compounds possessing anti-HIV activity

E. coli evolution studies may lead to better treatments

Researchers discover molecular "switch" in receptor that controls cell behavior

Mirimus develops enhanced tools for reversible gene suppression

‘Window for intervention’ to forestall hypertensive cognitive decline

JHI releases epic3 guidelines on infection prevention for healthcare professionals

Cancer cells that fuse with macrophages play key role in the spread of cancer

Eleven researchers receives 2014 DeLill Nasser Award for Professional Development in Genetics

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

Climate change may lead to decline in snail fever

Novel ISM strategy enables selection of potentially effective cancer therapies for patients

JHI released epic3 guidelines on infection prevention and control for range of healthcare professionals

UCSB anthropologists find successful hunting boosts testosterone, cortisol levels in Tsimane men

MIT assistant professor named Pew biomedical researcher of the month

Climate differences drive gene changes, find Virginia Bioinformatics Institute researchers

Cook Medical begins clinical study to evaluate removability of Evolution Esophageal Fully Covered Stent

New demographic data unveils extraordinary diversity of aging processes

Researchers produce erythrocyte progenitor cells by transducing two genes into iPS and ES cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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