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Human Y chromosome stays intact while chimp Y loses genes

The human and the chimpanzee Y chromosomes went their separate ways approximately 6 million years ago. But ever since this evolutionary parting, these two chromosomes have experienced different fates, new research indicates.

1 Sep 2005

Study suggests cirrhosis and liver disease nearly inevitable for people with hep C

Nearly 80 percent of chronic hepatitis C sufferers who have the disease for several decades will develop cirrhosis or end-stage liver disease later in life, according to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology.

1 Sep 2005

Charles Darwin was right and chimp gene map proves it

According to scientists who have mapped the complete chimp genome and compared it to the human gene map, there is little genetic difference between humans and chimps, but those differences count for a lot.

31 Aug 2005

Novel mechanism, called recursive splicing reveals how cells process large genes

Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns).

22 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

Faster and more objective way to examine the surfaces of fossilized teeth

Using a powerful microscope and computer software, a team of scientists from Johns Hopkins, the University of Arkansas, Worcester Polytechnic Institute and elsewhere has developed a faster and more objective way to examine the surfaces of fossilized teeth, a practice used to figure out the diets of our early ancestors.

10 Aug 2005

DDT resistance in flies carries no cost

For those concerned with the troublesome effects of genetic resistance to drugs and pesticides, the conventional wisdom of evolution offers a reassuring word: In the absence of the original chemical threat, most resistance mutations would cause a disadvantage to their hosts and might be expected to quickly leave the genetic landscape once the use of a drug or insecticide is suspended or withdrawn.

9 Aug 2005

New insights into dietary divergences between some of our human ancestors

A Penn State researcher is part of the team that developed techniques that have generated insights into dietary divergences between some of our human ancestors, allowing scientists to better understand the evolutionary path that led to the modern-day diets that humans consume.

3 Aug 2005

Primordial soup where life began on earth was hot and not cold

A new theory that explains why the language of our genes is more complex than it needs to be also suggests that the primordial soup where life began on earth was hot and not cold, as many scientists believe.

2 Aug 2005

Aging profile of the human brain differs greatly from that seen in chimpanzees

Researchers have found that the two primary areas of the human brain appear to age in radically different ways: The cortex used in higher-level thought undergoes more extensive changes with age than the cerebellum, which regulates basic processes such as heartbeat, breathing and balance.

2 Aug 2005

Aging and gene expression in the primate brain

While medical science and a healthy lifestyle can help increase life expectancy, many aspects of aging and longevity are beyond our control. Published this week in the open-access journal PLoS Biology, Michael Eisen and colleagues shed light on these genetic factors by identifying sets of genes whose expression changes with age in human and chimp brains.

2 Aug 2005

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

A defect in the mechanics of motors that build tiny cellular hairs is the basis of a serious genetic disorder, according to researchers at UC Davis and Simon Fraser University, Canada.

1 Aug 2005

Cats have no sweet tooth

According to British and U.S. scientists cats may like ice cream, but it is not the sugary taste that appeals to them, because they are genetically unable to taste sweet flavors.

28 Jul 2005

Spotting that nasty taste could well have saved our lives

Being able to distinguish the sweetness of oranges from the bitter taste of lemons may have evolved as a protection against eating poisonous plants, according to new genetic research.

27 Jul 2005

Multi-species genome comparison sheds new light on evolutionary processes

An international team that includes researchers from the National Human Genome Research Institute (NHGRI) has discovered that mammalian chromosomes have evolved by breaking at specific sites rather than randomly as long thought - and that many of the breakage hotspots are also involved in human cancer.

25 Jul 2005

Variation in HIV's ability to disable host defenses contributes to rapid evolution

One of the reasons HIV is so difficult to contain and treat is its rapid evolution. Understanding how host defenses and viral countermeasures contribute to that evolution is vital.

25 Jul 2005

Plant toxins in the diets of early humans drove the evolution of taste

Plant toxins in the diets of early humans drove the evolution of a bitter taste receptor better able to detect them, suggests new genetic research by scientists at University College London, Duke University Medical Center, and the German Institute of Human Nutrition.

25 Jul 2005

Hidden secrets on the nature and timing of genome evolution in mammals revealed

Breakages in chromosomes in mammalian evolution have occurred at preferred rather than random sites as long thought, and many of the sites are involved in human cancers, an international team of 25 scientists has discovered.

21 Jul 2005

Major stem cell discovery

Research published in Nature tomorrow (21 July) will outline for the first time the stem cell origin of the structure of the neck and shoulders in vertebrates.

20 Jul 2005

Tamiflu may treat avian flu virus

Experiments in mice show that an antiviral drug currently used against annual influenza strains also can suppress the deadly influenza virus that has spread from birds to humans, killing dozens of people in Vietnam, Cambodia and Thailand since early 2004.

18 Jul 2005