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New small molecule offers hope in combating antibiotic resistance

Researchers from the University of Oxford have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.

24 May 2024

Harnessing molecular pathways governed by key gene to enhance wheat yields

A study from the University of Adelaide has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

23 May 2024

Investigating the evolution of cell division mechanisms in Ichthyosporea

Cell division is fundamental to life, enabling growth, reproduction, and survival across all organisms, from single-celled bacteria to complex multicellular animals.

23 May 2024

Mammal-specific domain of the prion protein may hold clues to neurodegenerative diseases

A study from Bochum describes a mammal-specific domain of the prion protein and offers new approaches for research into neurodegenerative diseases.

23 May 2024

Study explores how different modes of cell division evolved in close relatives of fungi and animals

Cell division is one of the most fundamental processes of life. From bacteria to blue whales, every living being on Earth relies on cell division for growth, reproduction, and species survival.

23 May 2024

Research aims to better understand the origin of eosinophils

Eosinophils are specialized cells of our immune system. They are identified by their distinctive granules that stain red when treated with an acidic reagent, eosin, which gave them their name.

22 May 2024

New MOBE technology revolutionizes multiplexed genome editing

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

21 May 2024

Cancer researchers urged to embrace AI for groundbreaking insights and efficiency

A review in Nature Reviews Cancer emphasizes the necessity for cancer researchers to understand AI's potentials and limitations, detailing its applications and challenges in cancer research to aid non-computational biologists.

20 May 2024

Researchers trace the evolution of key plant protein in lignin synthesis

Scientists from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected.

17 May 2024

New rule of biology highlights benefits of instability in living organisms

A molecular biologist at the USC Dornsife College of Letters, Arts and Sciences may have found a new "rule of biology."

17 May 2024

H5N1 avian flu strain jumps to seals in Quebec, raising zoonotic fears

Study describes the unusual mortality of gray and harbor seals in Quebec due to a highly pathogenic avian influenza A (H5N1) strain, raising concerns about potential zoonotic spillover.

17 May 2024

Single measles jab up to 2.6 times more likely to be ineffective in C-section born children

The dynamics of measles immunity at birth and following vaccination.

15 May 2024

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs.

14 May 2024

Scientists unlock mystery behind a deadly strain of cholera bacteria

A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, claiming thousands of lives around the world every year, sickening millions -; and, with its persistence, baffling scientists.

14 May 2024

What is the ‘immune self,’ and how can this concept benefit immunological research?

A perspective review discusses the concept of the 'immune self' and how adaptive immune responses are influenced by self-similarity. The study emphasizes advances and challenges in defining self-similarity and its impact on immunological research.

13 May 2024

Perspective delves into the rising threat of the MPX virus

Scientist at NIAID reviews the escalating global prevalence of the MPX virus, detailing its biology and transmission modes, and the urgent need for comprehensive research to understand and control its spread effectively.

13 May 2024

Exploring the relationship between evolvability and species divergence

Ever since Darwin published his landmark theory of how species evolve, biologists have been fascinated with the intricate mechanisms that make evolution possible.

10 May 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of newly diagnosed and death cases.

7 May 2024

Advancing equity in cancer care: Lessons from NCI-DCCs' community outreach and engagement initiatives

Investigators at Dana-Farber Cancer Institute have examined the historical evolution of Community Outreach and Engagement initiatives at both the National Cancer Institute (NCI) and National Cancer Institute-Designated Cancer Centers (NCI-DCCs).

6 May 2024