Ex Vivo News and Research

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Repurposing drugs to outsmart cancers

In an article published today by SAGE Publishing, investigators from The Nagourney Cancer Institute and The Albert Einstein Israelite Hospital in São Paulo, Brazil, announced a new approach to identifying effective treatments for patients with advanced metastatic cancers. A drug commonly used to treat kidney and liver cancer was discovered effective for breast cancer, which may open new drug therapies to patients regardless of tumor type.

22 Mar 2019

Open-source solution for multiparametric optical mapping of the heart's electrical activity

An international research team from the George Washington University, U.S., and the Moscow Institute of Physics and Technology, Russia, has developed an open-source solution for multiparametric optical mapping of the heart's electrical activity.

22 Mar 2019

Anti-cancer immunotherapy could be used to fight HIV

Researchers at the University of Montreal Hospital Research Centre have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy.

19 Feb 2019

New study seeks to understand how colibactin causes cancer

For more than a decade, scientists have worked to understand the connection between colibactin, a compound produced by certain strains of E. coli, and colorectal cancer, but have been hampered by their inability to isolate the compound.

15 Feb 2019

Bruker launches new SKYSCAN 1273 benchtop 3D X-ray microscope

Bruker today announced the new SKYSCAN 1273 benchtop 3D X-ray microscope based on micro-computed tomography technology.

From Bruker BioSpin - NMR, EPR and Imaging 6 Feb 2019

New automated, high-throughput bioreactor system for lung regeneration analysis

New strides are being made toward the ex vivo growth of human lungs. In a new article published in Tissue Engineering, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers, researchers report the development of a high-throughput, automated, multichannel lung bioreactor that allows parallel culture of up to five human cell-populated isolated rat lung scaffolds.

29 Jan 2019

Sartorius launches BIOSTAT RM TX single-use bioreactor for consistent quality cellular products

Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry today announced the launch of the BIOSTAT RM TX single-use bioreactor, a new wave mixed system developed specifically for closed, automated expansion of consistent quality cell products such as ex vivo cellular immunotherapies.

From Sartorius 22 Jan 2019

Neuroscientists decipher how brain circuits optimize themselves

Human beings, like other animals, possess an enormous learning capacity that allows for the apprehension of new sensory information to master new skills or to adapt to an ever-changing environment.

2 Jan 2019

New approach to destroy HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus - it is their metabolic (or energy-producing) activity1 that enables the virus to multiply.

21 Dec 2018

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Study identifies specific neurological changes related to traumatic brain injury

Traumatic brain injury, or TBI, is often referred to as the "invisible injury" - while on the surface everything seems normal with brain structure, symptoms may present themselves in the behavior of the injured and cannot be explained.

17 Dec 2018

New strategy for developing cell replacement therapies to combat type 1 diabetes

Scientists have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very mobile and that their destiny is strongly influenced by their immediate environment.

29 Nov 2018

Scientists develop new surgical process for studying the thymus

Elisa Oltra, head of the Genetic Exppression and Immunity group of the Faculty of Medicine at the Catholic University of Valencia, in collaboration with Alejandro Caicedo, professor of the Department of Medicine of the University of Miami, have developed a surgical process which makes it possible to place functional fragments of the thymus in the anterior chamber of the eyes of mice.

26 Nov 2018

Research shows link between immune responses and environmental exposures early in life

The prevalence of allergic diseases has increased significantly over the last decades, creating substantial financial and societal burdens. Due to this, researchers are trying to discover new approaches to the prevention and treatment of these diseases.

22 Nov 2018

Researchers elucidate infection process of bacterial pathogen Clostridium difficile

Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells, thus destroying the protective mucosal barrier of the intestinal tract.

21 Nov 2018

First probabilistic atlas of thalamus nuclei to better understand the brain

A multidisciplinary study led by BCBL, a Basque research center, opens the door to the investigation of the structure and functions of human thalamic nuclei and their involvement in Alzheimer's, dyslexia, epilepsy, Huntington's and schizophrenia.

20 Nov 2018

Samara scholars assessed a new way of skin cancer early diagnostics

A team of scholars of Samara National Research University and Samara State Medical University as well as clinic specialists of Samara Regional Oncology Centre tested a new way of skin cancer early diagnostics with the help of original complex of three devices.

25 Oct 2018

Validation of non-invasive stent monitoring techniques

Researchers from the Research Institute Germans Trias i Pujol, the Biomedical Research Networking Center on Cardiovascular Diseases, the University of Barcelona and the the Universitat Politècnica de Catalunya have created a new field probe to detect in a non-invasive and non-ionizing way the presence of metallic stents as well as their potential structural failures through microwave spectrometry.

25 Oct 2018

Study reveals factors linked to the development of Crohn's disease

How cells talk to each other, and what they say, has long held fascination for Seema Khurana, professor of biology and biochemistry.

5 Oct 2018

CytoSen receives favorable response from FDA to its pre-IND meeting package for CSTD002-NK

CytoSen Therapeutics, a private biopharmaceutical company accelerating innovation in Natural Killer cell therapy, today announced it has received a favorable response from the U.S. Food and Drug Administration to its pre-Investigational New Drug meeting package for the proposed Phase 2 trial of CytoSen's adoptive NK cell therapy, CSTD002-NK, for the reduction of relapse in high risk acute myeloid leukemia or myelodysplastic syndrome in patients undergoing haploidentical hematopoietic stem cell transplantation.

27 Sep 2018

Ex Vivo News and Research

Repurposing drugs to outsmart cancers

Open-source solution for multiparametric optical mapping of the heart's electrical activity

Anti-cancer immunotherapy could be used to fight HIV

New study seeks to understand how colibactin causes cancer

Bruker launches new SKYSCAN 1273 benchtop 3D X-ray microscope

New automated, high-throughput bioreactor system for lung regeneration analysis

Sartorius launches BIOSTAT RM TX single-use bioreactor for consistent quality cellular products

Neuroscientists decipher how brain circuits optimize themselves

New approach to destroy HIV reservoirs

Potential combination therapy against rare disease of the bone marrow could improve treatment

Study identifies specific neurological changes related to traumatic brain injury

New strategy for developing cell replacement therapies to combat type 1 diabetes

Scientists develop new surgical process for studying the thymus

Research shows link between immune responses and environmental exposures early in life

Researchers elucidate infection process of bacterial pathogen Clostridium difficile

First probabilistic atlas of thalamus nuclei to better understand the brain

Samara scholars assessed a new way of skin cancer early diagnostics

Validation of non-invasive stent monitoring techniques

Study reveals factors linked to the development of Crohn's disease

CytoSen receives favorable response from FDA to its pre-IND meeting package for CSTD002-NK

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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