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Positive results from Metabolex' Phase 1 MBX-2982 clinical trial for treating type 2 diabetes

Metabolex, Inc., a biopharmaceutical company focused on the discovery and development of proprietary new medicines for the treatment of metabolic diseases, announced positive results from two multiple ascending dose Phase 1 clinical trials of MBX-2982.

14 Oct 2009

New soy germ-based ingredient improves menopausal symptoms

SE5-OH containing Natural S-equol, a novel soy germ-based ingredient in a supplement, improved menopausal symptoms, including significantly reducing hot flash frequency by nearly 59 percent, according to a peer-reviewed study in Japanese women.

9 Oct 2009

Cognitive behavioral therapy effective for bulimia and binge eating disorders

Although most people with bulimia and binge eating disorders wait many years before seeking help, a new review shows that psychological treatment can make a large difference — and that cognitive behavioral therapy (CBT) is the most effective talk therapy for these disorders.

6 Oct 2009

Dapagliflozin with metformin reduces glycosylated hemoglobin level and body weight

Results from a 24-week phase 3 clinical study demonstrated that the investigational drug dapagliflozin, added to metformin, demonstrated significant mean reductions in the primary endpoint, glycosylated hemoglobin level (HbA1c) and in the secondary endpoint, fasting plasma glucose (FPG) in patients with type 2 diabetes inadequately controlled with metformin alone, as compared to placebo plus metformin.

3 Oct 2009

Array BioPharma to present poster on ARRY-403 glucokinase activator

Array BioPharma Inc. today announced that a poster on ARRY-403, a novel, oral, glucokinase activator (GKA), will be presented at the European Association for the Study of Diabetes annual meeting, on October 2, 2009, in Vienna, Austria.

2 Oct 2009

Orexigen's Empatic Phase 2b results demonstrate weight loss

Orexigen Therapeutics, Inc. today announced that its 24-week, Phase 2b trial for Empatic(TM) (bupropion SR/zonisamide SR), the Company's second late stage investigational combination drug for the treatment of obesity, met its primary efficacy endpoint by demonstrating statistically significantly greater weight loss for both Empatic doses compared to monotherapies and placebo.

1 Oct 2009

Treatment of gestational diabetes benefits both infant and mother

A National Institutes of Health network study provided the first conclusive evidence that treating pregnant women who have even the mildest form of gestational diabetes can reduce the risk of common birth complications among infants, as well as blood pressure disorders among mothers.

1 Oct 2009

Former professional players have fewer risks of heart attacks

Former professional football players with large bodies don't appear to have the same risk factors for heart disease as their non-athletic counterparts, UT Southwestern Medical Center researchers have found in studying a group of National Football League (NFL) alumni.

30 Sep 2009

AFRESA Inhalation Powder and AFRESA Inhaler NDA under FDA review

AFRESA® (insulin human [rDNA origin]) Inhalation Powder is a well-tolerated, ultra rapid acting insulin able to more closely replicate normal glucose suppression than currently available insulins, according to data presented at the 45th Annual Meeting of the European Association for the Study of Diabetes.

30 Sep 2009

Diabetics should monitor their blood sugar levels to improve metabolic status

Diabetes patients should always control their own blood sugar values if this leads to improvements in their treatment. This is the view advocated by Michael Nauck of the Bad Lauterberg Diabetes Center and his coauthors in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2009; 106[37]: 587-94), who discuss sensible approaches to blood glucose self-monitoring.

29 Sep 2009

Januvia in combination with metformin or taken alone lowers blood sugar

A post-hoc analysis, presented at the 45th Annual Meeting of the European Association for the Study of Diabetes (EASD), of data pooled from studies of 104 weeks in duration showed ‘Januvia’ (sitagliptin), when taken alone or in combination with metformin, provided significant blood sugar lowering over two years.

29 Sep 2009

Research study links high-fructose diet to increased blood pressure in men

A high-fructose diet raises blood pressure in men, while a drug used to treat gout seems to protect against the blood pressure increase, according to research reported at the American Heart Association's 63rd High Blood Pressure Research Conference.

24 Sep 2009

Lexicon initiates Phase 2 clinical trial of LX4211 in patients with type 2 diabetes mellitus

Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering breakthrough treatments for human disease, obtained favorable results from recently completed Phase 1 studies of LX4211 and announced today that it has initiated a Phase 2 clinical trial of the drug candidate in patients with type 2 diabetes mellitus.

15 Sep 2009

Children with larger waists are more at risk of developing cardiovascular disease later in life

Children with more fat around their midsections could be at a higher risk of developing cardiovascular disease later in life, researchers say.

11 Sep 2009

Study on basic mechanisms that control fertility in worms may help to know how some woman regain their fertility after cancer treatment

Scientific dogma has long asserted that females are born with their entire lifetime's supply of eggs, and once they're gone, they're gone. New findings by researchers at Fred Hutchinson Cancer Research Center, published online Aug. 27 in Science, suggest that in nematode worms, at least, this does not hold true.

28 Aug 2009

Study reveals poor body satisfaction and increased risk of disordered weight control behaviors among 10 to 11 year old children

A study of 4254 Canadian schoolchildren has shown a direct association between BMI and satisfaction with their body shape. The research, published in the open access journal BMC Public Health, shows a linear response for girls, who were happiest when thinnest, and a U-shaped response for boys, who were unhappy when they were too skinny or too fat.

26 Aug 2009

Quality test for Guardian Technologies International's Signature Mapping TBDx system completed

Guardian Technologies International, Inc. (OTCBB: GDTI) today announced that its Software Quality Assurance Team has completed all unit, component, integration, and systems tests of Signature Mapping TBDx™ (TBDx™) in preparation for September clinical trials in South Africa.

26 Aug 2009

Virginia Tech researchers to help pre-diabetic adults begin resistance training for preventing diabetes

Systematic, progressive resistance training - also called strength training - is a safe and efficient way for middle-aged and older adults to improve their health. A Virginia Tech led research team that includes experts in behavior, exercise, physiology, and medicine is designing a program to help pre-diabetic adults begin and, most important, maintain resistance training in order to prevent diabetes.

26 Aug 2009

Health Fair 11 to offer free or low-cost health screenings

Visitors attending the Minnesota State Fair will find some great health deals when they stop by Health Fair 11 at the Fair. More than a dozen organizations will offer free or low-cost health screenings. Among the screenings are: cholesterol testing (non-fasting), diabetes screening (glucose -- non-fasting), blood pressure checks, blood typing, hearing and vision assessments, bone density and body fat measurements, and weight readings.

24 Aug 2009

High serum insulin levels linked with increased risk of prostate cancer

Demetrius Albanes, M.D., of the Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics at the National Cancer Institute in Bethesda, Md., and colleagues investigated the relationship of the level of serum insulin and glucose, as well as surrogate indices of insulin resistance, to the development of prostate cancer.

24 Aug 2009

Fasting News and Research

Positive results from Metabolex' Phase 1 MBX-2982 clinical trial for treating type 2 diabetes

New soy germ-based ingredient improves menopausal symptoms

Cognitive behavioral therapy effective for bulimia and binge eating disorders

Dapagliflozin with metformin reduces glycosylated hemoglobin level and body weight

Array BioPharma to present poster on ARRY-403 glucokinase activator

Orexigen's Empatic Phase 2b results demonstrate weight loss

Treatment of gestational diabetes benefits both infant and mother

Former professional players have fewer risks of heart attacks

AFRESA Inhalation Powder and AFRESA Inhaler NDA under FDA review

Diabetics should monitor their blood sugar levels to improve metabolic status

Januvia in combination with metformin or taken alone lowers blood sugar

Research study links high-fructose diet to increased blood pressure in men

Lexicon initiates Phase 2 clinical trial of LX4211 in patients with type 2 diabetes mellitus

Children with larger waists are more at risk of developing cardiovascular disease later in life

Study on basic mechanisms that control fertility in worms may help to know how some woman regain their fertility after cancer treatment

Study reveals poor body satisfaction and increased risk of disordered weight control behaviors among 10 to 11 year old children

Quality test for Guardian Technologies International's Signature Mapping TBDx system completed

Virginia Tech researchers to help pre-diabetic adults begin resistance training for preventing diabetes

Health Fair 11 to offer free or low-cost health screenings

High serum insulin levels linked with increased risk of prostate cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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