Fatigue News and Research

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Viewpoints: The case against Jenny Mccarthy's vaccine stand; apathy on HIV; defeating Alzheimer's

What do you call someone who sows misinformation, stokes fear, abets behavior that endangers people's health, extracts enormous visibility from doing so and then says the equivalent of "Who? Me?" I'm not aware of any common noun for a bad actor of this sort. But there's a proper noun: Jenny McCarthy (Frank Bruni, 4/21).

23 Apr 2014

Glaucoma drug may help reverse obesity-related vision loss in women

An inexpensive glaucoma drug, when added to a weight loss plan, can improve vision for women with a disorder called idiopathic intracranial hypertension (IIH), according to a study funded by the National Institutes of Health.

23 Apr 2014

Neoadjuvant targeted treatment shows feasibility for limited clear-cell RCC

Treating patients with nonmetastatic clear-cell renal cell carcinoma with the tyrosine kinase inhibitor axitinib could not only prevent disease progression, but also shrink tumours before surgery, show the results of a phase II trial.

22 Apr 2014

Sunitinib-related fatigue occurs early then tails off during RCC treatment

Patients beginning sunitinib treatment for advanced renal cell carcinoma should be warned that fatigue is likely to occur early, but that it is unlikely to worsen over the course of treatment, suggest US researchers in Cancer.

22 Apr 2014

Nocturnal incontinence poses major burden after female bladder reconstruction

Health-related quality of life is lower in women who have undergone radical cystectomy and neobladder reconstruction for bladder cancer than in the general female population, shows research.

22 Apr 2014

Researchers examine link between alcoholism and loss of muscle strength

Muscle weakness is a common symptom of both long-time alcoholics and patients with mitochondrial disease. Now researchers have found a common link: mitochondria that are unable to self-repair.

22 Apr 2014

DePuy Synthes CMF announces launch of Patient Specific Plates for Mandible

DePuy Synthes CMF, a leader in skeletal and soft tissue repair and reconstruction and part of the DePuy Synthes Companies of Johnson & Johnson, announced the launch of Patient Specific Plates for Mandible (PSPM), new plates that are customized based on surgeon specifications and individual patient anatomy.

21 Apr 2014

Scientists lay groundwork for understanding immune responses in Lyme disease patients

A team of scientists led by Johns Hopkins and Stanford University researchers has laid the groundwork for understanding how variations in immune responses to Lyme disease can contribute to the many different outcomes of this bacterial infection seen in individual patients. A report on the work appears online April 16 in PLOS One.

21 Apr 2014

XBiotech announces results from Phase I/II oncology study

XBiotech is announcing that results from its Phase I/II oncology study conducted at MD Anderson Cancer Center in Houston, TX were published today in Lancet Oncology. The featured article describes the outcome in 52 advanced cancer patients treated with Xilonix™, XBiotech's novel, non-cytotoxic, anti-tumor therapy.

18 Apr 2014

NICE recommends FIRMAGON for treating advanced hormone-dependent prostate cancer in adults with spinal metastases

The National Institute for Health and Care Excellence (NICE) today issued its Final Appraisal Determination (FAD) recommending FIRMAGON (degarelix) as an option for treating advanced hormone-dependent prostate cancer, only in adults with spinal metastases who present with signs or symptoms of spinal cord compression.

16 Apr 2014

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

Data from a late-breaking abstract presented at the International Liver CongressTM 2014 identifies a new compound, SBEL1, that has the ability to inhibit hepatitis C virus (HCV) activity in cells at several points in the virus' lifecycle.

15 Apr 2014

Researchers find link between patient satisfaction and SDM during radiation treatment

Playing an active role in their radiation treatment decisions leaves cancer patients feeling more satisfied with their care, and may even relieve psychological distress around the experience, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the journal Cancer.

15 Apr 2014

Scientists receive grant from Biogen Idec to study everyday activities in MS using actual reality

John DeLuca, PhD, and Yael Goverover, PhD, OT, have received a grant from Biogen Idec to study how persons with multiple sclerosis (MS) perform everyday life tasks. The grant, entitled "The Use of Actual Reality to Measure Everyday Life Functional Activity in Multiple Sclerosis" provides financial support to conduct this research.

15 Apr 2014

Experts connect sleep deprivation to elevated risk of developing diabetes

Excessive noise is a common cause for a loss of sleep. Now, experts connect sleep deprivation to an elevated risk of developing diabetes.

10 Apr 2014

Gilead Sciences announces positive results from LDV/SOF phase 2 studies on HCV infection

Gilead Sciences, Inc. (Nasdaq: GILD) today announced data from two Phase 2 studies evaluating investigational all-oral regimens containing the nucleotide analog polymerase inhibitor sofosbuvir (SOF) for the treatment of chronic hepatitis C virus (HCV) infection.

10 Apr 2014

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Janssen Research & Development, LLC ("Janssen") today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA™ (ibrutinib) to the U.S. Food and Drug Administration (FDA) by its collaboration partner Pharmacyclics, Inc.

8 Apr 2014

UCL scientists find new way to artificially control paralyzed muscles using light

A new way to artificially control muscles using light, with the potential to restore function to muscles paralysed by conditions such as motor neuron disease and spinal cord injury, has been developed by scientists at UCL and King's College London.

7 Apr 2014

1/3 of ICU patients develop depression that typically manifests as physical symptoms

A third of intensive care patients develop depression that typically manifests as physical, or somatic, symptoms such as weakness, appetite change, and fatigue, rather than psychological symptoms, according to one of the largest studies to investigate the mental health and functional outcomes of survivors of critical care, published in The Lancet Respiratory Medicine.

7 Apr 2014

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Astellas Pharma Inc. and Medivation Inc. today announced the submission of a variation to amend the European Marketing Authorization Application for XTANDI® (enzalutamide) capsules for the treatment of adult men with metastatic castration-resistant prostate cancer (mCRPC) who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated.

4 Apr 2014

Researchers identify possible way to prevent headaches of climbers

By monitoring blood flow in the brains of six climbers scaling Mount Kilimanjaro in Tanzania, German medical researchers have identified a possible way to prevent the headaches that are a common feature of altitude sickness. This work appears in the latest issue of JNIRS—Journal of Near Infrared Spectroscopy.

4 Apr 2014

Fatigue News and Research

Viewpoints: The case against Jenny Mccarthy's vaccine stand; apathy on HIV; defeating Alzheimer's

Glaucoma drug may help reverse obesity-related vision loss in women

Neoadjuvant targeted treatment shows feasibility for limited clear-cell RCC

Sunitinib-related fatigue occurs early then tails off during RCC treatment

Nocturnal incontinence poses major burden after female bladder reconstruction

Researchers examine link between alcoholism and loss of muscle strength

DePuy Synthes CMF announces launch of Patient Specific Plates for Mandible

Scientists lay groundwork for understanding immune responses in Lyme disease patients

XBiotech announces results from Phase I/II oncology study

NICE recommends FIRMAGON for treating advanced hormone-dependent prostate cancer in adults with spinal metastases

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

Researchers find link between patient satisfaction and SDM during radiation treatment

Scientists receive grant from Biogen Idec to study everyday activities in MS using actual reality

Experts connect sleep deprivation to elevated risk of developing diabetes

Gilead Sciences announces positive results from LDV/SOF phase 2 studies on HCV infection

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

UCL scientists find new way to artificially control paralyzed muscles using light

1/3 of ICU patients develop depression that typically manifests as physical symptoms

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Researchers identify possible way to prevent headaches of climbers

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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