Fermentation News and Research

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New drink targeted for diabetics, individuals with high blood sugar

Scientists in China are reporting development of a low-calorie, low-sugar vegetable juice custom-designed for millions of individuals with diabetes and pre-diabetic conditions that involve abnormally high blood sugar.

29 Mar 2009

Scientists manipulate bacteria into generating their own vaccine

Scientists have developed a way to manipulate bacteria so they will grow mutant sugar molecules on their cell surfaces that could be used against them as the key component in potent vaccines.

23 Feb 2009

Microbes within gut may hold key to one cause of obesity

In terms of diversity and sheer numbers, the microbes occupying the human gut easily dwarf the billions of people inhabiting the Earth.

19 Jan 2009

DNA vaccine for SARS achieves neutralizing responses in first U.S. human trial

Vical Incorporated (NASDAQ:VICL) today announced that results from a Phase I clinical trial of a DNA vaccine for severe acute respiratory syndrome (SARS), conducted by the National Institutes of Health (NIH) and published in the November 25 issue of Vaccine(1), demonstrated that the vaccine was well-tolerated, and induced neutralizing antibody responses in 80% of the vaccinees and T-cell immune responses in all vaccinees.

10 Dec 2008

New technologies improve supplies of drugs to combat malaria

Three emerging technologies have the potential to significantly improve supplies of drugs to combat malaria, according to a report published today.

18 Nov 2008

Researchers create synthetic heparin

Robert Linhardt has spent years stitching together minuscule carbohydrates to build a more pure and safer alternative to the commonly used and controversial blood thinner heparin. At the national conference of the American Chemical Society on August 17, 2008, Linhardt announced that his research team may have accomplished this task by building the first fully synthetic heparin. Their creation is the largest dose of heparin ever created in the lab.

17 Aug 2008

Almonds may improve digestive health

Almonds, as well as being high in vitamin E and other minerals, are also thought to have other health benefits, such as reducing cholesterol. Recently published work by the Institute of Food Research has identified potential prebiotic properties of almonds that could help improve our digestive health by increasing levels of beneficial gut bacteria.

30 Jun 2008

Biopharmaceutical manufacturing capacity to increase 66% in Europe by 2012, sccording to new report

Production capacity for biopharmaceutical manufacturing will expand an average of 46% over the next five years for mammalian production systems, according to a new report by BioPlan Associates.

2 Jun 2008

Demand for alternative sweeteners are increasing by 8% a year

The demand for alternative sweeteners to sugar is increasing at a rate of 8% per year. The market is showing more and more interest in natural sweeteners compared to synthetic ones. This has been reflected in a study carried out by researchers at the Universidad Miguel Hernández (UMH) in Elche, Alicante.

12 May 2008

Potential link found between bacteria found in the human digestive system and obesity

Obesity is more than a cosmetic concern because it increases a person's risk for developing high blood pressure, diabetes and many other serious health problems.

2 Apr 2008

Most people believe smallpox not an extinct disease

The vast majority of Scottish people interviewed in the streets of Edinburgh are unaware of one of the greatest achievements of medical science - the eradication of smallpox from the world over 40 years ago.

31 Mar 2008

Pectin-rich apple products shown to have anticarcinogenic effects on colon

The apples and apple juice you consume may have positive effects in one of the most unlikely places in the body – in the colon.

28 Mar 2008

How Staphylococcus aureus resists our natural defenses

Researchers at the University of Washington have uncovered how the bacterium Staphylococcus aureus, including the notorious MRSA (methicillin-resistant Staph aureus) "superbug" strains, resists our body's natural defenses against infection.

25 Mar 2008

Isocitric acid from fermentation of sunflower oil - a new building block for pharma?

The citric acid cycle, one of the most important metabolic processes in our bodies, was formulated in 1937. Since then, all of the intermediates have been produced in multigram quantities - with one exception, (2 R,3S)-isocitric acid.

4 Feb 2008

Genetic switches could lower cost of producing drugs, proteins

Bacteria have evolved complex mechanisms called quorum sensing systems that provide for cell-to-cell communication, an adaptation that allows them to wait until their population grows large enough before mounting an attack on a host or competing for nutrients.

23 Jan 2008

Researchers seek to make cavity-causing bacteria self-destruct

Bacteria that eat sugar and release cavity-causing acid onto teeth may soon be made dramatically more vulnerable to their own acid.

3 Jan 2008

Transporters may help delay diabetes-related retinal damage

Two transporters that deliver alternative energy sources to the eye may help delay retinal damage that can occur in diabetes, researchers say.

29 Nov 2007

More complete understanding of lactic acid production in muscle

In a paper published in The Journal of Physiology, Frank de Paoli and colleagues, working at the University of Aarhus in Denmark, add to the growing literature leading to a more complete understanding of the physiological role of lactic acid production in muscle.

1 Jun 2007

Sigma-Aldrich acquires Molecular Medicine BioServices

Sigma-Aldrich Corporation has announced that it has acquired Molecular Medicine BioServices Inc. (MMB), a biopharmaceutical contract manufacturing organization (CMO) located in Carlsbad, California, to further enhance the biologics capabilities within its SAFC Pharma business segment.

9 May 2007

Loss of a single gene in kidney cancer cells causes them to stop making mitochondria

Studying a rare inherited syndrome, researchers at Johns Hopkins have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread.

8 May 2007