Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

The adipose tissue dysfunction behind metabolically healthy obesity

A session at this year's Annual Meeting of the European Association for the Study of Diabetes will explore the latest data on the concept of metabolically healthy obesity (MHO) – more commonly known by the public as 'fat but fit'.

4 Oct 2023

New analytical tool could lead to a cure for idiopathic pulmonary fibrosis

Using a new recipe for growing blood vessels from living lung tissue in the lab, a University of Virginia School of Engineering and Applied Science research team has developed an analytical tool that could lead to a cure for idiopathic pulmonary fibrosis, or IPF, a lung-destroying disease.

3 Oct 2023

Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

Researchers describe the origin and fate of liver myofibroblasts

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer.

28 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

Study uncovers previously unknown compensatory mechanism in liver disease

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $10.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate risk factors for malignant arrhythmias in mitral valve prolapse.

26 Sep 2023

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown. It is not clear, however, whether these mutated viruses pose an increased risk to patients or are able to evade the vaccine.

25 Sep 2023

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

Is menopausal hormone therapy associated with non-alcoholic fatty liver disease?

The effects of menopausal hormone therapy on non-alcoholic fatty liver disease.

21 Sep 2023

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Dietary patterns, foods, and nutrients to ameliorate nonalcoholic fatty liver disease (NAFLD).

19 Sep 2023

Stem cell therapy shows promise in treating COVID-19 complications

The use of cell therapy to treat COVID-19 patients can reduce the risk of death from the disease by 60%, according to a systematic review and meta-analysis conducted by researchers at the University of São Paulo (USP) in Brazil, in partnership with colleagues in Germany and the United States.

19 Sep 2023

New implantable device carries insulin-producing islet cells to control diabetes

One promising approach to treating Type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections.

19 Sep 2023

HNP-1 may be a promising therapeutic agent for hypertensive left ventricular hypertrophy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Human neutrophil peptide-1 (HNP-1) is a commonly investigated therapeutic agent.

14 Sep 2023

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

Primary ciliary dyskenisia (PCD) is a rare genetic disease that causes the tiny hair-like filtration structures in the respiratory tract to stop working.

12 Sep 2023

Stem cells can be used to repair damaged lung tissue in COPD patients

For the first time, researchers have shown it is possible to repair damaged lung tissue in patients with chronic obstructive pulmonary disease (COPD) using the patients' own lung cells.

12 Sep 2023

Color of the phlegm can indicate degree of lung inflammation in patients with bronchiectasis

The color of the phlegm from patients with the lung disease bronchiectasis can indicate the degree of inflammation in their lungs and predict their future outcomes, according to new research presented at the European Respiratory Society International Congress in Milan, Italy.

11 Sep 2023

Study could pave the way to new treatments for people with compromised immune systems

New research led by Queen’s University Belfast has made a breakthrough in the field of microbiology, which could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis.

9 Sep 2023

Fibrosis News and Research

Further Reading

The adipose tissue dysfunction behind metabolically healthy obesity

New analytical tool could lead to a cure for idiopathic pulmonary fibrosis

Monocyte-derived macrophages play a crucial role in liver regeneration

Researchers describe the origin and fate of liver myofibroblasts

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Study uncovers previously unknown compensatory mechanism in liver disease

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Examining the cardiac pathology in fatal cases of yellow fever

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Is menopausal hormone therapy associated with non-alcoholic fatty liver disease?

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Stem cell therapy shows promise in treating COVID-19 complications

New implantable device carries insulin-producing islet cells to control diabetes

HNP-1 may be a promising therapeutic agent for hypertensive left ventricular hypertrophy

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

Stem cells can be used to repair damaged lung tissue in COPD patients

Color of the phlegm can indicate degree of lung inflammation in patients with bronchiectasis

Study could pave the way to new treatments for people with compromised immune systems

Breaking Barriers: ANDYSMANCLUB's Fight for Men's Mental Health on World Mental Health Day

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

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