Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

16-year-old uses supercomputing network to invent new drug cocktail for cystic fibrosis

While many 16-year-olds are content with PlayStation, Toronto-area student Marshall Zhang used the Canadian SCINET supercomputing network to invent a new drug cocktail which could one day help treat cystic fibrosis.

11 May 2011

Research suggests systemic sclerosis is an independent risk factor for atherosclerosis

A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis. Conventional cardiovascular risk factors such as age and hypertension predispose patients with systemic sclerosis to plaque build-up in the heart arteries similar to the general population. Details of this study are now available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

10 May 2011

Insmed first quarter revenues decrease to $1.6 million

Insmed Incorporated, a biopharmaceutical company, today reported results for the first quarter ended March 31, 2011.

10 May 2011

Dorsogluteal buttock site still most popular despite known potential for sciatic nerve injury

Seven out of ten hospital nurses who took part in a Canadian study used the dorsogluteal (DG) buttock site to administer intramuscular injections - despite the potential risks of sciatic nerve injury - with only 14% using the ventrogluteal (VG) hip site recommended by the nursing literature.

10 May 2011

Young new nurses more likely to follow latest VG site advice to administer intramuscular injections

Seven out of ten hospital nurses who took part in a Canadian study used the dorsogluteal buttock site to administer intramuscular injections - despite the potential risks of sciatic nerve injury - with only 14% using the ventrogluteal hip site recommended by the nursing literature.

9 May 2011

Six1 transcription factor an essential regulator in development of embryonic lung epithelial stem cells

Scientists at The Saban Research Institute of Children's Hospital Los Angeles have provided the first evidence that Six1 transcription factor is an essential regulator in the development of embryonic lung epithelial stem cells.

6 May 2011

Promedior's PRM-151 clinical data in idiopathic pulmonary fibrosis to be presented at ATS 2011

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, today announced that data from a clinical study of PRM-151 will be presented at the 2011 American Thoracic Society International Conference, being held May 13-18, 2011 in Denver, CO.

5 May 2011

FibroGen announces proof-of-principle for FG-4592 Phase 2 study in hemodialysis patients

FibroGen, Inc., today announced proof-of-principle for oral anemia therapy FG-4592, a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, in end-stage renal disease patients receiving hemodialysis.

4 May 2011

Exercise linked to improved lung status in children with cystic fibrosis

A small Johns Hopkins Children's Center study of children and teens with cystic fibrosis shows that simple exercise, individually tailored to each patient's preference and lifestyle, can help improve lung function and overall fitness.

4 May 2011

Animal studies reveal new route to treating heart disease

Scientists at Johns Hopkins have shown in laboratory experiments in mice that blocking the action of a signaling protein deep inside the heart’s muscle cells blunts the most serious ill effects of high blood pressure on the heart. These include heart muscle enlargement, scar tissue formation and loss of blood vessel growth.

2 May 2011

Pearl's PT003 Phase 2b study results in COPD to be presented at ATS meeting

Pearl Therapeutics Inc. announced today that complete results from the Company's Phase 2b study of PT003 in patients with moderate-to-very severe COPD will be presented during a late-breaker poster session at the upcoming annual meeting of the American Thoracic Society.

30 Apr 2011

Video games can serve as respiratory therapy for children with cystic fibrosis

Video games controlled by the player's breath can encourage youths with cystic fibrosis to use techniques that can help keep their airways clearer, according to a study to be presented Saturday, April 30, at the Pediatric Academic Societies annual meeting in Denver.

30 Apr 2011

Antiviral Drugs Advisory Committee recommends FDA to approve telaprevir for hepatitis C

Vertex Pharmaceuticals Incorporated announced that the Antiviral Drugs Advisory Committee to the U.S. Food and Drug Administration voted unanimously to recommend FDA approval of telaprevir for people with genotype 1 chronic hepatitis C.

29 Apr 2011

Drug subsidy issues out of PBS’ hands - almost

According to Health Minister Nicola Roxon, expensive drugs have never been automatically listed for subsidy and they can't be now when the government controlling expenses. She added that federal Labor has to balance competing priorities in health and every other department.

29 Apr 2011

Proteostasis acquires Harvard University's two novel protein target licenses

Proteostasis Therapeutics announced today that it has acquired two exclusive licenses from Harvard University to technologies for enhancing the activity of a key cellular protein clearance mechanism, the ubiquitin-proteasome pathway.

27 Apr 2011

Children, adolescents with liver disease may not benefit from vitamin E or metformin

In contrast to previous preliminary data, use of vitamin E or the diabetes drug metformin was not superior to placebo on a measured outcome for treating nonalcoholic fatty liver disease in children and adolescents, according to a study in the April 27 issue of JAMA.

27 Apr 2011

Pro-Pharmaceuticals receives method patent regarding DAVANAT in Japan

Pro-Pharmaceuticals, Inc., the leading developer of therapeutics that target Galectin proteins to treat cancer and fibrosis, today announced that the Japan Patent Office has accepted a new patent, No. 2002-574987, "Co-administration of a Polysaccharide with a Chemotherapy for the Treatment of Cancer". The patent protects, among other things, methods for reducing the toxicity of chemotherapies in which a polysaccharide, such as the Company's lead drug DAVANAT®, is co-administered with a chemotherapeutic agent to reduce toxicity of the chemotherapy.

25 Apr 2011

New genetic discovery in Pulmonary Fibrosis

A new discovery in a deadly lung disease may change the direction of research while uncovering increased risk for many patients and families. The Coalition for Pulmonary Fibrosis and the Pulmonary Fibrosis Foundation applaud the efforts of scientists that led to the discovery of a genetic variation associated with the MUC5B gene which may increase the risk of developing Pulmonary Fibrosis.

25 Apr 2011

PVT1 gene may help reduce diabetic nephropathy

A gene called PVT1 may help reduce the kidneys ability to filter blood, leading to kidney disease, kidney failure and death, according to a study published today by researchers at the Translational Genomics Research Institute.

25 Apr 2011

Creative approach can tackle bacterial infections in patients with cystic fibrosis

An over-the-counter drug used to treat diarrhea combined with minocycline, an antibiotic used to treat bacterial infections, could one day change the lives of those living with cystic fibrosis.

25 Apr 2011

Fibrosis News and Research

Further Reading

16-year-old uses supercomputing network to invent new drug cocktail for cystic fibrosis

Research suggests systemic sclerosis is an independent risk factor for atherosclerosis

Insmed first quarter revenues decrease to $1.6 million

Dorsogluteal buttock site still most popular despite known potential for sciatic nerve injury

Young new nurses more likely to follow latest VG site advice to administer intramuscular injections

Six1 transcription factor an essential regulator in development of embryonic lung epithelial stem cells

Promedior's PRM-151 clinical data in idiopathic pulmonary fibrosis to be presented at ATS 2011

FibroGen announces proof-of-principle for FG-4592 Phase 2 study in hemodialysis patients

Exercise linked to improved lung status in children with cystic fibrosis

Animal studies reveal new route to treating heart disease

Pearl's PT003 Phase 2b study results in COPD to be presented at ATS meeting

Video games can serve as respiratory therapy for children with cystic fibrosis

Antiviral Drugs Advisory Committee recommends FDA to approve telaprevir for hepatitis C

Drug subsidy issues out of PBS’ hands - almost

Proteostasis acquires Harvard University's two novel protein target licenses

Children, adolescents with liver disease may not benefit from vitamin E or metformin

Pro-Pharmaceuticals receives method patent regarding DAVANAT in Japan

New genetic discovery in Pulmonary Fibrosis

PVT1 gene may help reduce diabetic nephropathy

Creative approach can tackle bacterial infections in patients with cystic fibrosis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News