Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Single donor gifts lungs for two lung transplants

The University of Michigan Transplant Center celebrated a milestone recently, performing its 500th lung transplant. But there's much more to this story than a number.

17 Feb 2011

Sanofi-aventis, Sunnybrook enter agreement to develop and commercialize vasculotide

Sanofi-aventis and Sunnybrook Health Sciences Centre announced that they have entered into a research agreement and licensing option for vasculotide, an investigational compound to treat chronic wounds. This includes neuropathic diabetic foot ulcers caused by a lack of sensation and neuropathic ulcers that are complicated by peripheral arterial disease, commonly called neuroischemic diabetic foot ulcers.

16 Feb 2011

RPCs transplant appears to improve kidney structure and function in rat models

Transplanting autologous renal progenitor cells, into rat models with kidney damage from pyelonephritis - a type of urinary infection that has reached the kidney - has been found to improve kidney structure and function.

14 Feb 2011

Kamada reports positive interim results from Alpha-Antitrypsin Phase 2-3 trial to treat Alpha-1 deficiency

Kamada, a bio-pharmaceutical company engaged in the development, manufacturing and marketing of specialty life-saving therapeutics, announced today that it received the interim report of its phase 2-3 trial to treat Alpha-1 deficiency with its flag product, Alpha-Antitrypsin, delivered by inhalation.

14 Feb 2011

Registration open for idiopathic pulmonary fibrosis healthcare summit

The Pulmonary Fibrosis Foundation (PFF) announced today that registration is now open for the IPF Summit 2011: From Bench to Bedside. The conference will feature an innovative two-day continuing medical education (CME) program for physicians, researchers, and other health care professionals. Additionally there will be a separate one-day patient, family member, and caregiver program to address the growing educational needs of the idiopathic pulmonary fibrosis (IPF) community.

14 Feb 2011

Study shows beneficial anti-fibrotic effects of Pentraxin-2 in idiopathic pulmonary fibrosis

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry and Cell Biology entitled, "TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P."

14 Feb 2011

Study: Leptin resistance may help prevent ARDS, ALI development in patients with type II diabetes

Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome and acute lung injury in individuals with type II diabetes, according to a study conducted by researchers in Chicago.

13 Feb 2011

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

11 Feb 2011

Promedior initiates Phase 1b clinical study of PRM-151 in patients with IPF

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today that it has initiated a Phase 1b clinical study of PRM-151 to explore the safety, tolerability, pharmacokinetics, and phamacodynamics of PRM-151 in the treatment of patients with idiopathic pulmonary fibrosis.

11 Feb 2011

Life Sciences Discovery Fund announces nearly $600,000 in awards

The Life Sciences Discovery Fund (LSDF) today announced nearly $600,000 in awards to support commercial development of technologies to improve the diagnosis and management of major health conditions.

9 Feb 2011

DE-MRI holds promise for predicting risks of strokes

Researchers at the University of Utah's Comprehensive Arrhythmia and Research Management Center have found that delayed-enhancement magnetic resonance imaging holds promise for predicting the risks of strokes, the third leading cause of death in the U.S.

9 Feb 2011

Scientists awarded grant to study microbiology of Cystic Fibrosis pulmonary infection

Scientists at Queen's University Belfast have begun work into improving the lives of thousands of Cystic Fibrosis sufferers thanks to the award of a -1.74 million US-Ireland Research and Development Partnership grant.

4 Feb 2011

Queen's awarded £1.74 million grant to study microbiology of Cystic Fibrosis pulmonary infection

Scientists at Queen's University Belfast have begun work into improving the lives of thousands of Cystic Fibrosis sufferers thanks to the award of a £1.74 million US-Ireland Research and Development Partnership grant.

4 Feb 2011

DARA BioSciences' KRN5500 Phase 2 study in advanced cancer selected for presentation at ADEPT 2011

The Company announced that the University of Rochester in concert with ADEPT has selected the study results from the KRN5500 Phase 2 study to be presented at its March 25-26, 2011 conference. The presentation is entitled, "Management of Placebo Response in a Randomized Trial of KRN5500 in Patients with Neuropathic Pain and Cancer."

2 Feb 2011

Extensive, reversible changes in heart take place when exposed to low oxygen levels

From the highest mountaintop comes a new research report in the FASEB Journal that gets to the bottom of what happens to the hearts of people when exposed to low-levels of oxygen, such as those on Mount Everest or in the intensive care unit of a hospital.

1 Feb 2011

Cystic Fibrosis Canada hosts Kites in Flight celebration to raise awareness of CF

Cystic Fibrosis Canada (formerly known as the Canadian Cystic Fibrosis Foundation) is changing its look to increase awareness of the cause, and help Canadians with cystic fibrosis live longer, healthier lives.

29 Jan 2011

McGill, GSK enter collaborative research agreement on cystic fibrosis

McGill University and GlaxoSmithKline plc have signed a collaboration agreement to develop a potential breakthrough approach to treat cystic fibrosis, a fatal genetic disease. The trans-Atlantic effort between researchers from McGill's Faculty of Medicine and their GSK collaborators in the UK, will focus on developing molecules that could treat the disease by correcting the dysfunction caused by the mutated gene.

28 Jan 2011

TD2 and Flagship Biosciences offer combined oncology and pathology services

TGen Drug Development (TD2) and Flagship Biosciences today announced a strategic alliance that should help speed new drugs safely into human testing and quickly benefit cancer patients.

27 Jan 2011

Composer Fr-d-ric Chopin probably had temporal lobe epilepsy

The composer Fr-d-ric Chopin, who regularly hallucinated, probably had temporal lobe epilepsy throughout his short life, reveals research published online in Medical Humanities. Hallucinations typically feature in seizure disorders, they say.

25 Jan 2011

Breakthrough in understanding mechanisms behind hereditary alpha-1-antitrypsin deficiency

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have made a breakthrough in understanding the mechanisms behind the most severe form of hereditary emphysema and how protein treatments can improve the condition. The findings of this study may also lead to new treatments for patients with smoker's emphysema.

24 Jan 2011

Fibrosis News and Research

Further Reading

Single donor gifts lungs for two lung transplants

Sanofi-aventis, Sunnybrook enter agreement to develop and commercialize vasculotide

RPCs transplant appears to improve kidney structure and function in rat models

Kamada reports positive interim results from Alpha-Antitrypsin Phase 2-3 trial to treat Alpha-1 deficiency

Registration open for idiopathic pulmonary fibrosis healthcare summit

Study shows beneficial anti-fibrotic effects of Pentraxin-2 in idiopathic pulmonary fibrosis

Study: Leptin resistance may help prevent ARDS, ALI development in patients with type II diabetes

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

Promedior initiates Phase 1b clinical study of PRM-151 in patients with IPF

Life Sciences Discovery Fund announces nearly $600,000 in awards

DE-MRI holds promise for predicting risks of strokes

Scientists awarded grant to study microbiology of Cystic Fibrosis pulmonary infection

Queen's awarded £1.74 million grant to study microbiology of Cystic Fibrosis pulmonary infection

DARA BioSciences' KRN5500 Phase 2 study in advanced cancer selected for presentation at ADEPT 2011

Extensive, reversible changes in heart take place when exposed to low oxygen levels

Cystic Fibrosis Canada hosts Kites in Flight celebration to raise awareness of CF

McGill, GSK enter collaborative research agreement on cystic fibrosis

TD2 and Flagship Biosciences offer combined oncology and pathology services

Composer Fr-d-ric Chopin probably had temporal lobe epilepsy

Breakthrough in understanding mechanisms behind hereditary alpha-1-antitrypsin deficiency

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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