Finasteride News and Research

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Finasteride is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer in higher doses. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation.
Common factors that could change your PSA test results

Common factors that could change your PSA test results

Popular prostate drug has negative impact on men's overall health, study suggests

Popular prostate drug has negative impact on men's overall health, study suggests

Use of 5ARIs for prostatic enlargement not linked to increased suicide risk in older men

Use of 5ARIs for prostatic enlargement not linked to increased suicide risk in older men

Prolonged exposure to male hormone blockers increases risk of persistent erectile dysfunction

Prolonged exposure to male hormone blockers increases risk of persistent erectile dysfunction

Men who use finasteride to treat benign prostate enlargement experience worsening ED

Men who use finasteride to treat benign prostate enlargement experience worsening ED

Healthy men participating in Prostate Cancer Prevention Trial are most likely to undergo biopsy

Healthy men participating in Prostate Cancer Prevention Trial are most likely to undergo biopsy

Men with chronic inflammation in non-cancerous prostate tissue may have nearly twice risk of prostate cancer

Men with chronic inflammation in non-cancerous prostate tissue may have nearly twice risk of prostate cancer

Study: Chronic inflammation associated with aggressive prostate cancer

Study: Chronic inflammation associated with aggressive prostate cancer

NCI-PCPT explores survival of men on finasteride drug

NCI-PCPT explores survival of men on finasteride drug

Finasteride has ability to modulate alcohol intake, finds GW researcher

Finasteride has ability to modulate alcohol intake, finds GW researcher

Combination of novel drug therapy and PSA test can effectively detect prostate cancer

Combination of novel drug therapy and PSA test can effectively detect prostate cancer

Researchers develop and test new prostate cancer screening method

Researchers develop and test new prostate cancer screening method

Depressive symptoms, suicidal thoughts more prevalent among former finasteride users

Depressive symptoms, suicidal thoughts more prevalent among former finasteride users

Dutaseride may help prevent progression of early stage prostate cancer: Study

Dutaseride may help prevent progression of early stage prostate cancer: Study

KSU professor turns to nutrition to tackle prostate cancer

KSU professor turns to nutrition to tackle prostate cancer

Scientists identify molecular mechanism behind alcohol-induced blackouts

Scientists identify molecular mechanism behind alcohol-induced blackouts

Drugs for enlarged prostate raise cancer risk

Drugs for enlarged prostate raise cancer risk

Men with high DHA levels may face risk of developing aggressive prostate cancer

Men with high DHA levels may face risk of developing aggressive prostate cancer

PSA velocity is a poor predictor of prostate cancer

PSA velocity is a poor predictor of prostate cancer

Gene expression changes in prostate tissue surrounding cancer lesions may allow prostate cancer diagnosis

Gene expression changes in prostate tissue surrounding cancer lesions may allow prostate cancer diagnosis