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Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

Cancer patients often experience significant fluctuations in weight and lean body mass (LBM). Neglecting to account for these changes can prevent clinicians from obtaining precise data from molecular imaging, but a new method of measuring LBM takes changes in individual body composition into account for better staging of disease and therapy monitoring, say researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

15 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery.

14 Jun 2016

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jun 2016

Bruker showcases innovative NMR solutions for pharmaceutical industry at ENC 2015

At the 56th Experimental Nuclear Magnetic Resonance Conference, Bruker this week is show-casing several innovative drug discovery, drug development and process control solutions for small molecule NMR characterization in the pharmaceutical industry.

From Bruker BioSpin - NMR, EPR and Imaging 15 Mar 2016

New chemical probe could tag cells for detection by MRI

The need to non-invasively "see" and track cells in living persons is indisputable - a boon to both research and development of future therapies. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients.

15 Mar 2016

Pittcon 2016: Bruker showcases new products and analytical solutions

This week at Pittcon 2016, Bruker is showcasing new products and analytical solutions for core Applied & Pharma markets, for our Nanoanalysis, Microscopy & Advanced Materials Research markets, as well as new after-market services and life-cycle support solutions for our customers.

From Bruker BioSpin - NMR, EPR and Imaging 8 Mar 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

JGU employs new particle accelerator to enhance research into radiopharmaceutical chemistry

A new particle accelerator will further enhance the research landscape at Johannes Gutenberg University Mainz. It is to be employed to conduct research into potential applications of medical relevance.

5 Jan 2016

New protein supplement lowers cholesterol, prevents osteoporosis

Scientists developed a supplement to maintain optimal health that contributes to the growth and development of children and adolescents. It also prevents osteoporosis and certain cancers such as breast and prostate.

5 Nov 2015

New approach to imaging glucose uptake activity in single living cells

Researchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance. In a recent study published in Angewandte Chemie International Edition, Associate Professor of Chemistry Wei Min's team developed a new glucose analogue that can mimic the natural glucose, and imaged its uptake as energy source by living cancer cells, neurons and tissues at the single cell level.

20 Jul 2015

New pre-validated fluorinated fragment library boosts drug screening efficiency

Researchers engaged in drug discovery can now benefit from a new library of fluorinated compounds with superior drug-like characteristics...

From Thermo Fisher Scientific Inc. 14 Apr 2015

Washington University researchers develop way to apply light-based therapy to reach deep tumors

Light long has been used to treat cancer. But phototherapy is only effective where light easily can reach, limiting its use to cancers of the skin and in areas accessible with an endoscope, such as the gastrointestinal tract.

12 Mar 2015

MIT researchers devise new way to make complex emulsions

MIT researchers have devised a new way to make complex liquid mixtures, known as emulsions, that could have many applications in drug delivery, sensing, cleaning up pollutants, and performing chemical reactions.

27 Feb 2015

New type of engineered insulin could improve treatment for diabetes patients

For patients with diabetes, insulin is critical to maintaining good health and normal blood-sugar levels. However, it's not an ideal solution because it can be difficult for patients to determine exactly how much insulin they need to prevent their blood sugar from swinging too high or too low.

11 Feb 2015

Fluorine News and Research

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

PET imaging can help identify autoimmune inflammation in MS

Bruker showcases innovative NMR solutions for pharmaceutical industry at ENC 2015

New chemical probe could tag cells for detection by MRI

Pittcon 2016: Bruker showcases new products and analytical solutions

Researchers suggest ways to make TB drugs more efficacious against mutations

JGU employs new particle accelerator to enhance research into radiopharmaceutical chemistry

New protein supplement lowers cholesterol, prevents osteoporosis

New approach to imaging glucose uptake activity in single living cells

New pre-validated fluorinated fragment library boosts drug screening efficiency

Washington University researchers develop way to apply light-based therapy to reach deep tumors

MIT researchers devise new way to make complex emulsions

New type of engineered insulin could improve treatment for diabetes patients

UB researchers design nanoparticle that may open door for new 'hypermodal' imaging systems

Radioactive tracer with PET MRI imaging helps prostate cancer patients avoid unnecessary surgery

Catylix, Aspira Scientific partner to develop and commercialize new fluorination products

European approval process for Eckert & Ziegler’s gallium-68 generator is successfully completed

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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