Fluorophore News and Research

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Research offers new understanding related to effects of chemical conjugation on stability of ADCs

Wolfe Laboratories today announced the presentation of an abstract related to its research efforts surrounding antibody-drug conjugates at the 245th National Meeting of the American Chemical Society, held April 7-11 in New Orleans.

9 Apr 2013

Study sheds light on role of retinoic acid in tissue development

In a ground-breaking study, researchers from the RIKEN Brain Science Institute in Japan report a new technique that allows them to visualize the distribution of retinoic acid in a live zebrafish embryo, in real-time.

9 Apr 2013

Microscope system designed to acquire very low-light bioluminescence images introduced in North America by Olympus America

A benchtop commercial microscope system designed to acquire very low-light bioluminescence images has now been introduced in North America by Olympus America. The LV200 stand-alone microscope system is already being used to capture images of living cells and tissues by researchers in Europe and Japan.

From Evident Corporation - Life Sciences 29 Nov 2012

A reliable way to replicate α-synuclein aggregation on cell membranes in Parkinson's disease patients

The accumulation of α-synuclein, a small, negatively charged protein, in neural cells, is one of the hallmarks of Parkinson's disease. It has been suggested that oligomeric α-synuclein causes membranes to become permeable, or to form channels on the outer cell membrane.

19 Jan 2012

New fluorescent tool can track mysterious workings of cellular RNAs

The ability to tag proteins with a green fluorescent light to watch how they behave inside cells so revolutionized the understanding of protein biology that it earned the scientific teams who developed the technique Nobel Prizes in 2008.

30 Jul 2011

Novel FRET biosensor allows measurement of intraorganellar glutathione potentials in living cells

In work published in the June 2011 issue of Experimental Biology and Medicine, Kolossov, Spring and their co-investigators - a multidisciplinary team within the Institute for Genomic Biology at the University of Illinois - have transferred the concept of redox-sensitive Green Fluorescent Proteins (GFPs) to a quantitative F-rster resonance energy transfer (FRET) imaging platform.

8 Jun 2011

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

Developing drugs to combat or cure human disease often involves a phase of testing with mice, so being able to peer clearly into a living mouse's innards has real value.

30 May 2011

MTTI obtains exclusive license for novel fluorescence dyes from Massachusetts General Hospital

Molecular Targeting Technologies, Inc., announced that it has obtained an exclusive license from the Massachusetts General Hospital for novel fluorescence dyes developed by Scott Hilderbrand, Ph.D. Fangwei Shao, Ph.D., and Ralph Weissleder, Ph.D. M.D.

11 May 2011

Research sheds light on molecular movements of neural transporters

A team of scientists from Columbia University College of Physicians and Surgeons and Weill Cornell Medical College has shed light on the molecular workings of transporter proteins, molecular machines embedded in the cell membranes of neurons that modulate the transfer of signals between cells and recycle neurotransmitters.

25 Apr 2011

Scientists to develop ultra-rapid sexually transmitted infection detection system for clinics

Scientists from the University of Southampton have secured funding to develop an ultra-rapid sexually transmitted infection (STI) detection system for clinics that can detect STIs in under 15 minutes.

9 Dec 2010

Research may lead to better treatments for depression and substance abuse

In what has been hailed as a breakthrough, scientists from Columbia University Medical Center and Weill Cornell Medical College have outlined the molecular mechanism of membrane transport. The research shows how a protein transforms its shape to transport substances across the cell membrane in order to regulate transmission of the brain's messages across the synaptic gap from one neuron to another.

11 Jun 2010

PositiveID acquires intellectual property rights and assets of Easy Check Medical Diagnostics

PositiveID Corporation announced today that it has acquired intellectual property rights and assets of Easy Check Medical Diagnostics, LLC, to expand its portfolio of non-invasive glucose-level testing products and diabetes management tools under development. Easy Check has two primary products under development: the Easy Check breath glucose detection system and the iGlucose™ wireless communication device.

17 Feb 2010

PositiveID Corporation to add complementary non-invasive glucose-level testing technologies to Healthid division

PositiveID Corporation announced today that it plans to expand its HealthID division by adding products and tools for the daily management of diabetes. In addition to the continued development of its in vivo glucose-sensing RFID microchip to detect glucose levels in the human body, the Company is planning to broaden its technology platform by adding complementary non-invasive glucose-level testing technologies.

13 Jan 2010

Micronics inks license agreement with Biosearch Technologies

Micronics, Inc., a leading developer of point-of-care molecular diagnostic products, announced today that it has entered into a license agreement with Biosearch Technologies, Inc. (Biosearch) for the right to make, have made, use and sell Micronics’ products that incorporate Biosearch’s proprietary fluorophores and quencher dyes for nucleic acid assays. Under the terms of the worldwide license, Biosearch has granted Micronics a royalty-free use of certain of its chemistries for inclusion in Micronics’ infectious disease tests for sale in underdeveloped countries.

28 Oct 2009

New type of probe enables visualization of single ribonucleic acid

Biomedical engineers have developed a new type of probe that allows them to visualize single ribonucleic acid (RNA) molecules within live cells more easily than existing methods.

6 Apr 2009

Fluorescent anesthetic compound brings new avenues for drug discovery

A collaboration of University of Pennsylvania and University of Wisconsin chemists and anesthesiologists have identified a fluorescent anesthetic compound that will assist researchers in obtaining more precise information about how anesthetics work in the body and will provide a means to more rapidly test new anesthetic compounds in the search for safer and more effective drugs.

6 Apr 2009

Near-infrared nanoparticles shine a bright light on cancer

A new nanoparticle-enabled imaging method for breast cancer has been developed by a team of scientists from Penn State. Their research, utilizing encapsulated fluorescent molecules in calcium phosphate nanoparticles and nontoxic near infrared (NIR) imaging, appears in the journal ACS Nano.

27 Oct 2008