Fluoroquinolone is a type of drug used to prevent and treat infections. Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture. This risk is further increased in those over age 60, in kidney, heart, and lung transplant recipients, and with use of concomitant steroid therapy.
Scientists from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy.
A new three-drug, all-oral, six-month treatment is providing hope to patients in Tajikistan with highly drug-resistant forms of tuberculosis, which until now had limited treatment options and poor prognosis.
The definition of extensively drug-resistant tuberculosis (XDR-TB) has been revised by the World Health Organization's Global TB Programme, who have also defined pre-XDR-TB for the first time, highlighting the seriousness of these forms of TB.
As the search for effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitors continues, a recent study by Yale University School of Medicine researchers published on the preprint server bioRxiv in October 2020 reports the inhibitory effect of the drug merofloxacin on frameshifting during SARS-CoV-2 replication.
Goblet cells are epithelial cells that produce mucins and disperse tears which help the surface of eyes maintain the wet environment. Goblet cells are closely related to autoimmune disease including dry eyes and chemical burns. Therefore, it is very important to examine the status of goblet cells to better understand and diagnose ocular disease.
The American Thoracic Society, Centers for Disease Control and Prevention, European Respiratory Society and the Infectious Diseases Society of America have published an official clinical guideline on the treatment of drug-resistant tuberculosis in the Nov. 15 American Journal of Respiratory and Critical Care Medicine.
The American Thoracic Society and the Infectious Diseases Society of America have published an official clinical guideline on the diagnosis and treatment of adults with community acquired pneumonia (CAP) in the ATS's Oct. 1 American Journal of Respiratory and Critical Care Medicine.
Investigators have now shown that only half of patients presenting with sinus, throat, or ear infections at different treatment centers received the recommended first-line antibiotics, well below the industry standard of 80 percent.
It looks like it’s time to pay the piper. The first extensively drug-resistant (XDR) strain of Salmonella typhimurium, called ST313 sublineage II.1, has cropped up in the Democratic Republic of Congo (DRC). This fails to respond to any of the antibiotics that are commonly used in the DRC, except for ciprofloxacin. And to make things worse, one sample has been isolated that shows incomplete response even to this last drug.
Scientists have shown for the first time a link between two types of heart problems and one of the most commonly prescribed classes of antibiotics.
The River Thames is rapidly becoming a breeding pool for antibiotic-resistant bacteria, according to a new study, which underlines the urgent need to cut down the amount of antibiotics currently being discharge into the river by at least 80% to arrest this trend.
A recent study of over 1,000 healthy women with no symptoms of urinary tract infections showed nearly 9 percent carried multi-drug resistant Escherichia coli strains in their guts.
Virulent and multi-drug resistant strains of Escherichia coli can thrive in women’s gut even without any symptoms, a new study found.
In a surprising observation, a team of Australian scientists found that one in five silver gulls in Australia harbored antibiotic-resistant bacteria, which could cause a wave of serious human infections. This comes against a background of increasing alarm over the emergence of antibiotic resistance in many common bacterial species.
A million times a year, pneumonia sends American adults to the hospital. And while antibiotics help save lives, a new study shows two-thirds receive more antibiotics than they probably need.
In time for the World Tuberculosis (TB) Day 2019 on Sunday, March 24th, Bruker today announced the launch of an important further innovation in the field of tuberculosis diagnostics.
Brazil's Ministry of Health received reports of 11,524 outbreaks of foodborne diseases between 2000 and 2015, with 219,909 individuals falling sick and 167 dying from the diseases in question.
The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment
The U.S. Food and Drug Administration today is requiring safety labeling changes for a class of antibiotics called fluoroquinolones to strengthen the warnings about the risks of mental health side effects and serious blood sugar disturbances, and make these warnings more consistent across the labeling for all fluoroquinolones taken by mouth or given by injection.
Rates of C. difficile infections have decreased 36% in hospitals across Canada, although the virulent NAP1 strain associated with severe illness and deaths is the most common strain, according to research published in CMAJ.