Folic Acid News and Research

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Folic acid is a B vitamin. It helps the body make healthy new cells. Everyone needs folic acid. For women who may get pregnant, it is really important. When a woman has enough folic acid in her body before and during pregnancy, it can prevent major birth defects of her baby's brain or spine.

Foods with folic acid in them include leafy green vegetables, fruits, dried beans, peas and nuts. Enriched breads, cereals and other grain products also contain folic acid. If you don't get enough folic acid from the foods you eat, you can also take it as a dietary supplement.

Extra intake of iron may not benefit pregnant women, except when anemic

Although universal prenatal supplementation with iron is recommended, an extra intake of iron does not noticeably benefit pregnant women, except when they are anemic. This was observed by researchers of the Institute of Tropical Medicine Antwerp and colleagues who followed more than a thousand pregnant women in Burkina Faso.

11 Mar 2011

Allos reaches SPA agreement with FDA for FOLOTYN Phase 3 trial in PTCL

Allos Therapeutics, Inc. today announced that the Company has reached agreement with the U.S. Food and Drug Administration (FDA) under its Special Protocol Assessment (SPA) process for the design of the Company's Phase 3 clinical trial of FOLOTYN® (pralatrexate injection) in patients with previously undiagnosed peripheral T-cell lymphoma (PTCL).

4 Mar 2011

'Real world' guidelines may effectively prevent cardiovascular disease in women

Practical medical advice that works in the "real world" may more effectively prevent cardiovascular disease in women than recommendations based only on findings in clinical research settings, according to the 2011 update to the American Heart Association's cardiovascular disease prevention guidelines for women.

15 Feb 2011

USDA nutrient dosage recommendations not sufficient, says USANA

USANA Health Sciences, Inc. commends the USDA for recognizing that nutritional gaps are common in the average American diet and that dietary supplementation can play a vital role in filling those gaps. However, USANA scientists and advising physicians caution that many important nutrients were not included in the recently published Dietary Guidelines for Americans, 2010 and that the USDA dosage recommendations are not sufficient to improve and maintain overall health.

15 Feb 2011

More research needed to determine link between folic acid and breast cancer

Seven-year study demonstrates clear benefits of fetal surgery to treat spina bifida in babies

Results of a landmark, seven-year National Institutes of Health-funded trial, Management of Myelomeningocele Study (MOMS), demonstrate clear benefit for babies who undergo fetal surgery to treat spina bifida, the most common birth defect in the central nervous system.

11 Feb 2011

Women with high folic acid levels may impact child's risk of developing asthma

Recent Norwegian research suggests that there may be a connection between high levels of folic acid in pregnant mothers and the development of asthma in their children. However, the researchers stress that pregnant women should continue to take folic acid supplements.

10 Feb 2011

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Eli Lilly and Company and Bristol-Myers Squibb Company announced today that they have stopped enrollment in one of their two global Phase III studies evaluating necitumumab, an investigational anti-cancer agent, as a first-line treatment for advanced non-small cell lung cancer (NSCLC).

3 Feb 2011

FOLOTYN Phase 2 peripheral T-cell lymphoma study results published in Journal of Clinical Oncology

Allos Therapeutics, Inc. today announced that the Journal of Clinical Oncology has published data from the Company's pivotal Phase 2 PROPEL study demonstrating clinical activity of FOLOTYN® (pralatrexate injection) in patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

20 Jan 2011

Study shows risky knowledge gaps, deficits in dietary supplements among pregnant women

Research conducted by the Chair of Nutritional Medicine at the Technische Universitaet Muenchen indicates there are knowledge gaps: According to this study, pregnant women often start taking sensible dietary supplements too late or not at all. At the same time, other micronutrients are unwittingly overdosed whose effects during pregnancy have not yet been studied.

19 Jan 2011

Beer cheers for health: Study look at beer, Mediterranean diet and heart

A new study shows that people who drink moderate amounts of beer, ale or lager reduce their risk of high blood pressure and diabetes. The study involved 1,249 volunteers over 57 years old who combined a Mediterranean diet (fish, olive oil, and fruits and vegetables) with exercise and up to a pint of beer a day. People, who drank beer in moderation, had a lower body fat content.

17 Jan 2011

Close pregnancies increase autism risk: Study

According to a new study published in the February issue of Paediatrics, children born within one year of an older sibling may be three times more likely to be diagnosed with autism.

10 Jan 2011

Spectrum submits FUSILEV sNDA for treatment of colorectal cancer

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in oncology, today announced it submitted a supplemental New Drug Application with the U.S. Food and Drug Administration (FDA) for a Ready-to-Use formulation of FUSILEV (levoleucovorin) for Injection.

5 Jan 2011

People with high RBC folate levels more likely to have two tumor-suppressing genes

People with higher levels of folate in their red blood cells were more likely to have two tumor-suppressing genes shut down by methylation, a chemical off switch for genes, researchers report in the December issue of Cancer Prevention Research.

22 Dec 2010

Maternal prenatal supplements boost child's intellectual and motor function

In an area where iron deficiency is prevalent, children of mothers in rural Nepal who received prenatal iron, folic acid and vitamin A supplementation performed better on measures of intellectual and motor functioning compared to offspring of mothers who received vitamin A alone, according to a study in the December 22/29 issue of JAMA.

22 Dec 2010

Prenatal iron-folic acid supplementation increases intellectual, motor function in children

In developing countries where iron deficiency is prevalent, prenatal iron-folic acid supplementation increased offspring intellectual and motor functioning during school age, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

22 Dec 2010

Bayer's SAFYRAL oral contraceptive receives FDA approval

Bayer HealthCare Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration (FDA) has approved a new oral contraceptive (OC), SAFYRAL™ (drospirenone 3 mg/ ethinyl estradiol 30 mcg/ levomefolate calcium 451 mcg tablets and levomefolate calcium 451 mcg tablets). In women who choose an OC for birth control, SAFYRAL raises folate levels for the purpose of reducing the risk of rare neural tube defects (NTDs) in a pregnancy conceived while taking SAFYRAL or shortly after discontinuing it.

17 Dec 2010

$Allos Therapeutics reports new analysis of PROPEL trial data of FOLOTYN in patients with refractory PTCL$

Allos Therapeutics reports new analysis of PROPEL trial data of FOLOTYN in patients with refractory PTCL

Allos Therapeutics, Inc. today reported new analysis of data from the Company's pivotal PROPEL trial of FOLOTYN (pralatrexate injection) in patients with relapsed or refractory peripheral T-cell lymphoma at the 52nd American Society of Hematology Annual Meeting in Orlando, Florida.

6 Dec 2010

$Updated Phase 1 study results of FOLOTYN in patients with refractory CTCL presented at ASH 2010$

Updated Phase 1 study results of FOLOTYN in patients with refractory CTCL presented at ASH 2010

Allos Therapeutics, Inc. today reported updated results from the Company's Phase 1 dose-finding study of FOLOTYN® (pralatrexate injection) which supports the selection of 15 mg/m2 weekly for three weeks out of a four-week cycle as the optimal starting dose and schedule for further evaluation in patients with relapsed or refractory cutaneous T-cell lymphoma. Data were presented at the 52nd American Society of Hematology Annual Meeting in Orlando, Florida.

6 Dec 2010

$Pivotal PROPEL trial data of FOLOTYN in patients with refractory PTCL reported at ASH Annual Meeting$

Pivotal PROPEL trial data of FOLOTYN in patients with refractory PTCL reported at ASH Annual Meeting

Allos Therapeutics, Inc. today reported new analyses of data from the Company's pivotal PROPEL trial of FOLOTYN (pralatrexate injection) in patients with relapsed or refractory peripheral T-cell lymphoma at the 52nd American Society of Hematology Annual Meeting held in Orlando, Florida.

6 Dec 2010

Folic Acid News and Research

Further Reading

Extra intake of iron may not benefit pregnant women, except when anemic

Allos reaches SPA agreement with FDA for FOLOTYN Phase 3 trial in PTCL

'Real world' guidelines may effectively prevent cardiovascular disease in women

USDA nutrient dosage recommendations not sufficient, says USANA

More research needed to determine link between folic acid and breast cancer

Seven-year study demonstrates clear benefits of fetal surgery to treat spina bifida in babies

Women with high folic acid levels may impact child's risk of developing asthma

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

FOLOTYN Phase 2 peripheral T-cell lymphoma study results published in Journal of Clinical Oncology

Study shows risky knowledge gaps, deficits in dietary supplements among pregnant women

Beer cheers for health: Study look at beer, Mediterranean diet and heart

Close pregnancies increase autism risk: Study

Spectrum submits FUSILEV sNDA for treatment of colorectal cancer

People with high RBC folate levels more likely to have two tumor-suppressing genes

Maternal prenatal supplements boost child's intellectual and motor function

Prenatal iron-folic acid supplementation increases intellectual, motor function in children

Bayer's SAFYRAL oral contraceptive receives FDA approval

Allos Therapeutics reports new analysis of PROPEL trial data of FOLOTYN in patients with refractory PTCL

Updated Phase 1 study results of FOLOTYN in patients with refractory CTCL presented at ASH 2010

Pivotal PROPEL trial data of FOLOTYN in patients with refractory PTCL reported at ASH Annual Meeting

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