Fungal Infection News and Research

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Study finds new method can improve chemo survival

Seeking to find a way to lessen patients’ vulnerability to deadly infections following chemotherapy, researchers at the Stanford University School of Medicine have figured out a way to boost the immune function in animals following such treatments.

21 Dec 2004

All patients in study clear parasite that causes African sleeping sickness

Immtech International has announced that all 30 patients participating in the concluded Phase IIb extended dose regimen arm of its clinical trial of DB289 for treating African sleeping sickness cleared the parasite that causes African sleeping sickness within the treatment period, with no significant adverse results reported.

11 Nov 2004

Testosterone may impede immunity

Decreasing testosterone boosts immunity because testosterone helps control T-lymphocytes, the attack cells of the immune system, according to Mayo Clinic-led research in laboratory animals.

8 Nov 2004

Research has identified Dectin-1 as the beta-glucan receptor on immune cells

This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of Dectin-1 as the beta-glucan receptor may also provide a novel strategy for combating fungal infections.

10 Oct 2004

FDA reinforces use of Sustiva in first-line HIV combination therapy

Bristol-Myers Squibb has announced that Sustiva® (efavirenz) has received approval from the U.S. Food and Drug Administration to include new long-term virologic and clinical data from BMS Study 006 in its prescribing information.

26 Aug 2004

European funding to study how yeasts such as Candida cause infections among hospital patients

Dr Fritz Mühlschlegel, Reader in Medical Microbiology in the Biosciences Department at Kent and Consultant Medical Microbiologist in the East Kent NHS Trust, and Dr Daniel Poullain from Lille’s Medical School have been awarded 315,106 euros under the EU’s Interreg Programme to study the mechanisms by which fungal pathogens cause disease.

21 Jul 2004

The best way to avoid infection from mosquito bites is to flick not squash

An article published in this month's New England Journal of Medicine suggests that the best way to avoid infection from mosquito bites is to actually flick them away rather than squashing them into the skin.

19 Jul 2004

35 million Americans have fungal nail infection underneath their toenails

An estimated 35 million Americans have an active, live infection known as onychomycosis (fungal nail infection) underneath their toenails

29 Jun 2004

Once-daily treatment with Alvesco (ciclesonide) in asthma patients has no effect on normal adrenal function

New data presented at the American Thoracic Society’s 2004 International Conference show that once-daily treatment with the investigational therapy Alvesco (ciclesonide) in mild-to-moderate asthma patients has no effect on normal adrenal function, as demonstrated by measurements of the hypothalamic-pituitary-adrenal (HPA)-axis.

24 May 2004

Immtech signs agreement with CombinatoRx to test Immtech compounds as potential cancer treatment

Immtech International, Inc. announced today that it signed an agreement with CombinatoRx of Boston, Massachusetts to screen its lead aromatic cationic compounds, DB289 and DB75, for activity against various cancers.

5 May 2004

Time matters when treating fungal infections in newborns

A new UCLA study shows that ‘time matters’ when treating fungal infections in neonates and that earlier treatment can mean the difference between life and death.

1 May 2004