Furosemide News and Research

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Furosemide is a diuretic (water pill), a type of anthranilic derivative and loop diuretic with antihypertensive effect. Furosemide blocks the Na-K-Cl cotransporter (NKCC) in the luminal membrane of the thick ascending limb of the loop of Henle in the kidney, by binding to the Cl-binding site located in the cotransporter's transmembrane domain, thereby inhibiting reabsorption of sodium, chloride, potassium ions and water. This agent reduces plasma and extracellular fluid volume resulting in decreased blood pressure and cardiac output.
Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

Study shows new treatment option for heart failure fluid overload

Study shows new treatment option for heart failure fluid overload

Reprieve Cardiovascular announces results of clinical trials in patients with acute heart failure

Reprieve Cardiovascular announces results of clinical trials in patients with acute heart failure

Drug therapy for stable heart failure patients can be simplified by stopping diuretics

Drug therapy for stable heart failure patients can be simplified by stopping diuretics

Harris Health System expert offers guidance to prevent drug-induced photosensitivity

Harris Health System expert offers guidance to prevent drug-induced photosensitivity

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Combining decongestion markers may guide HF hospital discharge

Combining decongestion markers may guide HF hospital discharge

Validus, Wood Creek announce acquisition of U.S. rights to several Sanofi US products

Validus, Wood Creek announce acquisition of U.S. rights to several Sanofi US products

Unituxin (dinutuximab) granted EC Marketing Authorisation for treatment of childhood neuroblastoma

Unituxin (dinutuximab) granted EC Marketing Authorisation for treatment of childhood neuroblastoma

Potassium supplements with loop diuretics increase survival rates of heart failure patients

Potassium supplements with loop diuretics increase survival rates of heart failure patients

Usability study for semi-disposable patch pump completed for subcutaneous furosemide therapy

Usability study for semi-disposable patch pump completed for subcutaneous furosemide therapy

Anticholinergic drugs might increase risk of cognitive impairment, death in older people

Anticholinergic drugs might increase risk of cognitive impairment, death in older people

Decision Resources: 52% of surveyed cardiologists identify furosemide as efficacious acute heart failure therapy

Decision Resources: 52% of surveyed cardiologists identify furosemide as efficacious acute heart failure therapy

FDA accepts Merck's JANUMET extended-release formulation NDA for type 2 diabetes

FDA accepts Merck's JANUMET extended-release formulation NDA for type 2 diabetes

FDA approves Novartis' Amturnide for treatment of high blood pressure

FDA approves Novartis' Amturnide for treatment of high blood pressure

CRF announces additional featured trials to be presented at Transcatheter Cardiovascular Therapeutics 2010

CRF announces additional featured trials to be presented at Transcatheter Cardiovascular Therapeutics 2010

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

POZEN receives milestone payment from AstraZeneca for FDA approval of VIMOVO

POZEN receives milestone payment from AstraZeneca for FDA approval of VIMOVO

VIMOVO delayed-release tablets receive FDA approval

VIMOVO delayed-release tablets receive FDA approval

Parents lack understanding of causes, signs and symptoms of dehydration in children

Parents lack understanding of causes, signs and symptoms of dehydration in children