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Mild pain killer blocks action of key protein required for hearing

A Rice University study has found that the aspirin-like drug diflunisal blocks the action of prestin, a key protein that is required for hearing.

5 Sep 2017

NYIT professor awarded multi-year NIH grant for bone-healing research

NYIT has been awarded $442,000 to pursue research into a gene critical in the formation and healing of bones.

5 Sep 2017

High levels of suPAR protein shown to be likely cause of kidney damage in children

High levels of a protein known as suPAR, which has been shown to be a marker and likely cause of kidney damage, is as reliably predictive in children as in adults, according to results of a study published online today in JAMA Pediatrics, a clinical publication of the American Medical Association.

5 Sep 2017

Novel, ultra-rare damaging genetic variants may contribute to eating disorders

By combining whole exome sequencing, machine learning, and network analysis, researchers have identified new, ultra-rare gene mutations within specific biological pathways that may contribute to eating disorders.

5 Sep 2017

Higher intake of red meat, poultry linked to greater diabetes risk

While a plant-based diet is generally considered healthier than a meat-based diet in preventing the risk of diabetes, not all meats affect the risk equally.

5 Sep 2017

Research provides novel insights into bacterial toxins

A toxin produced by a bacterium that causes urinary tract infections is related to, yet different in key ways from, the toxin that causes whooping cough, according to new research.

5 Sep 2017

Largest ever genetic study paves way for potential osteoporosis treatment

Scientists are honing in on a potential treatment for osteoporosis, after performing the largest ever genetic study of the common age-related bone-thinning disease.

5 Sep 2017

Scientists show how receptors for drugs act inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

5 Sep 2017

Japanese scientists uncover new genetic marker for schizophrenia

Schizophrenia is a complicated disease that often appears in early adulthood. Although scientists have not traced the genetic causes, more than 80% of schizophrenia cases are considered to have a hereditary cause.

5 Sep 2017

Combined DNA and protein 'liquid biopsy' more accurate in identifying early-stage pancreatic cancer

Johns Hopkins scientists say they have developed a blood test that spots tumor-specific DNA and protein biomarkers for early-stage pancreatic cancer.

4 Sep 2017

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes.

4 Sep 2017

Unfolded protein response could be cause of metabolic disorders, say researchers

The cell's response to unfolded or misfolded proteins could be a cause, rather than a consequence, of metabolic disorders, report researchers at the Medical University of South Carolina in an article published online ahead of print on September 4, 2017 by Nature Structural & Molecular Biology.

4 Sep 2017

Scientists identify key molecule for neurotransmitter release in synapses

The contact areas between nerve cells are called synapses. What happens there lies at the heart of communication between nerve cells. Communication starts with the release of chemical messengers known as neurotransmitters at these synapses.

4 Sep 2017

Veterans affected with combat-related PTSD show changes in blood-based microRNA, study finds

Individuals affected with PTSD (Post-Traumatic Stress Disorder) demonstrate changes in microRNA (miRNA) molecules associated with gene regulation.

4 Sep 2017

Genetics of circadian rhythms found to have effect on migraine

People with a specific variation in the CLOCK gene have more migraines under financial stress. This work, the first time that the genetics of circadian rhythms has been shown to have an effect on migraine, is presented at the ECNP conference in Paris.

4 Sep 2017