GPCR News and Research

RSS

Scientists create powerful method for 'directed evolution' of molecules

UNC School of Medicine scientists created a powerful new "directed evolution" technique for the rapid development of scientific tools and new treatments for many diseases.

5 Jul 2019

Study sheds light on rhodopsin dynamics in the retina

Photoreceptor cells in our eyes can adjust to both weak and strong light levels, but we still don't know exactly how they do it.

24 Jun 2019

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

A team of researchers led by Kazuhiro Suzuki from the Immunology Frontier Research Center at Osaka University discovered the COMMD3/8 complex as a molecule involved in immune cell migration, clarifying that the complex plays a critical role in the establishment of immune responses.

31 May 2019

Scientists develop maps of two melatonin receptors vital for sleep, other biological processes

An international team of researchers used an X-ray laser at the Department of Energy’s SLAC National Accelerator Laboratory to create the first detailed maps of two melatonin receptors that tell our bodies when to go to sleep or wake up and guide other biological processes.

26 Apr 2019

Scientists develop new accurate computational method to enhance drug target stability

Scientists from the Moscow Institute of Physics and Technology, the Skolkovo Institute of Science and Technology, and the University of Southern California have developed a new computational method for the design of thermally stable G protein-coupled receptors that are of great help in creating new drugs.

30 Mar 2019

Newly developed bioluminescence sensors pave way for drug discovery

Canadian researchers, working in partnership with Brazilian colleagues, have developed 13 bioluminescence sensors for use in testing the effectiveness of new medical drugs in the laboratory.

2 Mar 2019

Developing the Next Generation of Water-soluble DREADDs

An interview with James Flanaghan, discussing the uses of DREADDs in neurobiological research and the advantages of water-soluble ligands.

From Hello Bio 19 Dec 2018

Researchers discover two proteins essential for development of skeletal muscle

All vertebrates need muscles to function; they are the most abundant tissue in the human body and are integral to movement.

12 Nov 2018

Study shows how cellular waste disposal processes also promote inflammation

A study conducted at the University of California has revealed how cells use G-protein-coupled receptors (GPCRs) and their waste disposal systems to mediate inflammation.

19 Sep 2018

Study gives new insights into how cells leverage GPCRs to control inflammation

G-protein-coupled receptors are everywhere in our bodies. They are embedded in our cell membranes, where they act as signal transducers, allowing cells to respond to their external environments.

19 Sep 2018

New method may speed up development of novel drugs

Researchers of the University of Würzburg have developed a method that makes it possible to measure the activation of receptors in a very short time. This might speed up the development of new drugs.

6 Sep 2018

Discovery will allow scientists to target hypoxia in cancer

Researchers have discovered a new GPCR that will allow them to target hypoxia in cancer, offering a new, less harmful treatment for patients.

27 Aug 2018

Researchers take major step in eliminating cancer without harming healthy tissue

A major advance towards targeting cancer without harming healthy tissue has been discovered by University of Bristol researchers.

24 Aug 2018

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Omeros Corporation announced today that the European Medicines Agency's Committee for Orphan Medicinal Products issued a positive opinion recommending orphan drug designation of OMS721 for treatment in hematopoietic stem cell transplantation.

25 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

New study finds way to help treat alcohol addiction and ease withdrawal symptoms

According to a new study by Scripps Research scientists, activating a receptor found in brain cells may help treat alcohol addiction and ease some withdrawal symptoms. The researchers studied the effects of activating the receptor in alcohol-addicted rats and reported the results today in the journal eNeuro.

27 Jun 2018

GPCR News and Research

Scientists create powerful method for 'directed evolution' of molecules

Study sheds light on rhodopsin dynamics in the retina

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

Scientists develop maps of two melatonin receptors vital for sleep, other biological processes

Scientists develop new accurate computational method to enhance drug target stability

Newly developed bioluminescence sensors pave way for drug discovery

Developing the Next Generation of Water-soluble DREADDs

Researchers discover two proteins essential for development of skeletal muscle

Study shows how cellular waste disposal processes also promote inflammation

Study gives new insights into how cells leverage GPCRs to control inflammation

New method may speed up development of novel drugs

Discovery will allow scientists to target hypoxia in cancer

Researchers take major step in eliminating cancer without harming healthy tissue

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

New study finds way to help treat alcohol addiction and ease withdrawal symptoms

Heart failure severity could vary based on the body's nitric oxide levels

Genetic differences can influence efficiency of medicines

Newly solved glucagon receptor structure provides most accurate template for drug design

Discovery of key protein’s structure may help improve drug design

From surviving to thriving: a framework for long-term success in people with HIV

Kevin Broadbelt

Michael Stryker

Latest News