Gabapentin News and Research

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Gabapentin (brand name Neurontin) is a medication originally developed for the treatment of epilepsy. Presently, gabapentin is widely used to relieve pain, especially neuropathic pain.

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder?

Researchers assessed the efficacy and compared the relative effectiveness of various pharmacological treatments for alcohol use disorder.

8 Nov 2023

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

In a recent review published in Cell, a group of authors delved into the complexities of menopause, assessed its global impacts on health, and evaluated the effectiveness and safety of current treatments, emphasizing the importance of further research.

6 Sep 2023

New drug shows promise for treating chronic neuropathic pain

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

2 Aug 2023

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Researchers investigated whether functional connectivity between glioblastoma and the brain affected neural circuits.

9 May 2023

Bariatric surgery may be an effective treatment for obese people at risk of diabetes, peripheral neuropathy

For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a Michigan Medicine study shows.

10 Apr 2023

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

A prescription drug that helps Lore Wilkinson walk and talk despite a rare muscle disease cost her so little for more than a decade that she didn't even use her insurance to pay for it.

22 Feb 2023

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Many people living on the streets in Philadelphia's Kensington neighborhood — the largest open-air drug market on the East Coast — are in full-blown addiction, openly snorting, smoking, or injecting illicit drugs, hunched over crates or on stoops. Syringes litter sidewalks, and the stench of urine fouls the air.

15 Feb 2023

Social motivator effectively rescues rehab participation in mice after spinal cord injury

A research finding in mice that the drug gabapentin improved rehab compliance after spinal cord injury led scientists to a related, unexpected discovery: Injured mice that didn't receive gabapentin and declined to exercise by themselves were willing to hop on the treadmill when presented with a group rehab option.

3 Oct 2022

How common is pediatric cannabis use and what are the risks?

New research evaluated the recent usage of marijuana and its derivative products, their effects and clinical manifestations, perceptions, pharmaceutics, epidemiological studies, and the long-term ramifications in pediatric populations.

12 Jul 2022

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

Researchers call for nursing homes to shift to non-medication-based methods to help dementia patients

A decade-long effort to reduce medication risks for nursing home residents with dementia has paid off in some ways – but produced unintended consequences that now need addressing, new research shows.

31 May 2022

Gabapentin treatment may enhance recovery of movement after a stroke

The drug gabapentin, currently prescribed to control seizures and reduce nerve pain, may enhance recovery of movement after a stroke by helping neurons on the undamaged side of the brain take up the signaling work of lost cells, new research in mice suggests.

23 May 2022

Existing drug may reduce damage after spinal cord injury, research shows

Scientists from the University of Birmingham have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord.

20 May 2022

‘Injections, injections, injections’: Troubling questions follow closure of sprawling pain clinic chain

On May 13 of last year, the cellphones of thousands of California residents undergoing treatment for chronic pain lit up with a terse text message: "Due to unforeseen circumstances, Lags Medical Centers will be closing effective May 19, 2021."

22 Feb 2022

Study analyzes trends in overdose deaths from use of non-benzodiazepines and gabapentinoids

With an alarming rise in the number of prescriptions filled for non-benzo sleeping/z-drugs and anti-epilepsy gabapentinoids over the last two decades, researchers at Columbia University Mailman School of Public Health aimed to fill in the gap in knowledge in the proportion of overdose deaths involving those medications and learn more about their co-usage with other substances across U.S. demographics categories.

16 Feb 2022

Beta-amyloid deposits found in young patients with COVID-19

A new study describes the finding that patients of COVID-19 exhibit large amounts of focal β-amyloid deposits in their neocortical tissues.

25 Jan 2022

AAN issues new guideline on oral and topical treatments for painful diabetic neuropathy

Diabetic neuropathy refers to nerve damage due to diabetes and it may lead to pain and numbness, most often in the hands and feet. To help neurologists and other doctors determine the best treatment for people with diabetic neuropathy, the American Academy of Neurology (AAN) has issued a guideline on oral and topical treatments for painful diabetic neuropathy.

28 Dec 2021

Internal tremors and vibrations symptoms among people with long-COVID

In a recent study, researchers aimed to identify a potentially important cluster of similar patient-reported symptoms from PASC-affected individuals.

8 Dec 2021