Gadolinium News and Research

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CHMP recommends approval of Gilenya for treatment of multiple sclerosis in children, adolescents

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended approval of Gilenya (fingolimod) for the treatment of children and adolescents 10 to 17 years of age with relapsing remitting forms of multiple sclerosis.

24 Sep 2018

NIH funds CWRU to investigate new imaging approach for diagnosing peripheral arterial disease

Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a common and potentially serious circulatory problem. More than 200 million people worldwide suffer from the condition.

18 Sep 2018

Left atrial fibrosis may indicate high risk of arrhythmias in trained endurance athletes

Left atrial fibrosis may explain the increased risk of arrhythmias seen in highly trained endurance athletes, according to research presented today at ESC Congress 2018.

27 Aug 2018

Researchers develop new system for effective cancer diagnosis and treatment

A research group consisting of scientists from NUST MISIS, the Technical University of Munich, Helmholtz Zentrum München, the University of Duisburg-Essen, and the University of Oldenburg has developed a system that allows doctors to both improve the accuracy of diagnosing malignant cells and to provide additional opportunities for cancer treatment.

24 Aug 2018

Scientists explore ways for drug therapies to reach deadly brain tumors

The blood-brain barrier is a specialized network of vascular and brain cells that acts as the brain's security system, helping to safeguard the brain and regulate the flow of substances into and out of it.

15 Aug 2018

Researchers study use of MRI-guided focused ultrasound to open blood-brain barrier

In the first such clinical trial in the United States, physician-scientists with the University of Maryland School of Medicine are investigating the use of MRI-guided focused ultrasound to open the blood-brain barrier.

10 Aug 2018

Study: Gadolinium deposition in brain not associated with dosage

Investigators at Children's Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium administered but rather these changes are seen in association with other factors such as the presence of brain tumors and treatment using brain irradiation. Results of the study were just published in the journal, Radiology.

15 May 2018

Researchers discover substance that could lead to cheaper and smaller MRI machines

Researchers at the National High Magnetic Field Laboratory have discovered a substance that could help MRI machines evolve from today’s bulky behemoths to hand-held scanners straight out of “Star Trek.”

2 May 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Alternative MRI contrast agent shows promising results in NIH study

NIH-supported researchers at Massachusetts General Hospital are studying an alternative to the contrast agents currently used for magnetic resonance imaging.

14 Feb 2018

New five-minute procedure to scan blood vessels offers hope for claustrophobic patients

Doctors have developed a new five-minute procedure to scan the blood vessels which offers hope for claustrophobic patients unable to tolerate the conventional longer test. The research is presented today at CMR 2018.

6 Feb 2018

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

A team of Massachusetts General Hospital researchers has developed a potential alternative to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging.

15 Nov 2017

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Celgene Corporation recently announced results from two phase 3 trials evaluating the efficacy and safety of the drug ozanimod.

10 Nov 2017

So much care it hurts: Unneeded scans, therapy, surgery only add to patients’ ills

When Annie Dennison was diagnosed with breast cancer last year, she readily followed advice from her medical team, agreeing to harsh treatments in the hope of curing her disease.

23 Oct 2017

New MRI contrast agent differentiates between aggressive and slow-growing breast cancers

A new magnetic resonance imaging (MRI) contrast agent being tested by researchers at Case Western Reserve University not only pinpoints breast cancers at early stages but differentiates between aggressive and slow-growing types.

25 Sep 2017

Preclinical research using 1 Tesla desktop MRI

An interview with Dr. Ichio Aoki, National Institutes for Quantum and Radiological Science and Technology.

From Bruker BioSpin - NMR, EPR and Imaging 17 Aug 2017

New multicolor MRI approach could aid disease diagnosis

Researchers at Case Western Reserve University School of Medicine have developed a method that could make magnetic resonance imaging--MRI--multicolor.

17 Aug 2017

Gadolinium-based MRI contrast agents deposit in the brain

The International Society for Magnetic Resonance in Medicine has provided new guidance in the use of contrast agents during MRI scans. Emerging research suggests gadolinium-based contrast agents, injected in a patient's veins to brighten tissues in MRI images, accumulate in the brain.

7 Aug 2017

Experiments in big animals show efficacy of new non-toxic MRI contrast agent

The top causes of death worldwide, ischemic heart diseases and stroke, together with another major source of illness, that is cancer, require proper imaging of blood vessels.

31 Jul 2017

Scientists create new probe for imaging proteins involved in fibrogenesis

Organs respond to injuries with the formation of new fibrous tissue, which can result in scarring. This process called fibrogenesis can now be monitored noninvasively on a molecular level, as American scientists report in the journal Angewandte Chemie.

19 Jul 2017