Gangrene News and Research

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Gangrene is a type of tissue death which occurs due to loss of blood supply. This may affect any part of the body but usually affects the peripheral extremities like feet, toes, fingers, hands, penis etc.

Leg pain can mean peripheral arterial disease

David Dow thought he was having back problems, and that his legs were hurting as a result. As it turns out, that pain may have saved his life.

4 Apr 2007

Performing x-rays using iodine dye increases risk for kidney failure

Performing x-rays using iodine dye places patients with impaired kidney function at increased risk for kidney failure. Known as Contrast-Induced Nephropathy (ne-FROPP-a- thee) or ''CIN,'' this complication is the third most common cause of hospital-acquired kidney failure in the United States and Europe, accounting for 10-12 percent of all such cases.

1 Apr 2007

Garlic offers hope in cystic fibrosis infection

Garlic has been hailed a wonder drug for centuries and has been used to prevent gangrene, treat high blood pressure, ward off common colds and is even believed by some to have cancer-fighting properties.

31 Jan 2007

Drug trial fiasco induced immune system overload in patients

The doctors who treated six British men in a trial of a drug in March which went horribly wrong, say they believe the men suffered an immune system overreaction known as a cytokine storm.

15 Aug 2006

Atorvastatin may increase new blood vessel formation

Systemic sclerosis (SSc), also known as scleroderma, is an uncommon and confounding disease characterized by excessive fibrous tissue formation and vascular abnormalities.

6 Jun 2006

FDA fast track status for Alfimeprase

Nuvelo Inc. today announced that it has been granted fast track designation by the U.S. Food and Drug Administration (FDA) for its lead product candidate, alfimeprase, for the treatment of acute peripheral arterial occlusion (PAO), or "leg attack."

23 Jan 2006

Discovery of genetic mechanism that causes new arteries to grow in response to blocked arteries

Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to grow in response to blocked arteries.

2 Dec 2005

Early changes in the oxygenation of the skin may help predict foot disease in diabetes patients

Foot ulcerations are one of the most serious complications of diabetes, resulting in more than 80,000 lower-leg amputations each year in the U.S. alone.

14 Nov 2005

Mayo Clinic researchers find earliest sign of nerve change due to diabetes

Mayo Clinic researchers have found that subtle change in nerve conduction is the first reliable sign of nerve complications from diabetes and that this change can be measured long before other symptoms or signs of nerve damage develop.

3 Oct 2005

Legs For Life free national screening program can save legs

The screening is essential for diabetics in order to prevent amputation, heart attack and stroke, because one-third have PAD, but most do not present classic symptoms.

1 Sep 2005

Giving oxygen may do more harm than good

Doctors and paramedics who give their patients oxygen - the most commonly administered "drug" in the world - may be doing more harm than good, a Queen's University researcher contends.

11 Jul 2005

Trial to evaluate modern stent technologies over balloon angioplasty for peripheral arterial disease

The first patient undergoes treatment today in a new prospective randomised trial, called the SUPER Study, to compare stenting with balloon angioplasty in patients with superficial femoral artery (SFA) occlusions caused by peripheral artery disease (PAD).

28 Apr 2005

Genzyme begins gene transfer trial for peripheral arterial disease

Genzyme Corporation announced today that the first patient has been treated in a new phase 2 clinical trial examining the safety and effectiveness of locally delivered gene transfer for patients with peripheral arterial disease.

24 Feb 2005

Do cholesterol-reducing drugs decrease the risk of heart attacks and strokes in diabetics?

International researchers will, for the first time, present findings from the landmark 4D trial about whether a cholesterol-reducing drug decreases the risk of heart attacks and strokes with type 2 diabetics on dialysis at the American Society of Nephrology’s 37th Annual Meeting and Scientific Exposition in St. Louis, Missouri.

1 Nov 2004