Gastroesophageal Reflux Disease News and Research

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Gastroesophageal reflux disease (GERD) is a more serious form of gastroesophageal reflux (GER), which is common. GER occurs when the lower esophageal sphincter (LES) opens spontaneously, for varying periods of time, or does not close properly and stomach contents rise up into the esophagus. GER is also called acid reflux or acid regurgitation, because digestive juices—called acids—rise up with the food. The esophagus is the tube that carries food from the mouth to the stomach. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach.

Hackensack Meridian JFK University Medical Center launches new Gastroesophageal Reflux and Motility Program

Hackensack Meridian JFK University Medical Center today announced the opening of its new Gastroesophageal Reflux and Motility Program to provide expert diagnosis and treatment of gastroesophageal reflux disease, commonly known as GERD, and other, related motility disorders that affect the muscles in the gastrointestinal tract.

20 Mar 2023

Gut microbiomes and mental health: how do they interact?

A new study published in the journal Frontiers in Medicine reviewed recent literature on the link between gut microbiota, the brain, and neurological disorders.

19 Mar 2023

What is the gastrointestinal impact of Long Covid?

Researchers assessed gastrointestinal outcomes associated with COVID-19.

9 Mar 2023

Is physical activity associated with the risks of hospitalization for common health conditions?

Researchers assessed the relationship between physical activity levels and hospitalization risk.

20 Feb 2023

Ingestible sensor could offer an alternative to invasive procedures used to diagnose motility disorders

Engineers at MIT and Caltech have demonstrated an ingestible sensor whose location can be monitored as it moves through the digestive tract, an advance that could help doctors more easily diagnose gastrointestinal motility disorders such as constipation, gastroesophageal reflux disease, and gastroparesis.

13 Feb 2023

Protein adduction and p53 tumor suppressor inhibition

Researchers assessed the impact of protein adduction on p53 tumor suppressor inhibition.

27 Jan 2023

Study reveals an increase in the prevalence of digestive diseases

Data from a new pan-European study on the burden of digestive diseases, presented today at UEG Week 2022 and published in the United European Gastroenterology Journal, highlights a worrying increase in the prevalence of several digestive diseases since 2000. These include chronic liver diseases, pancreatitis, gastroesophageal reflux disease, gastritis, vascular intestinal disorders and coeliac disease in children. In addition, the incidence and mortality rates for all digestive cancers combined have increased by 26% and 17% respectively in the period 2000-2019.

10 Oct 2022

NYU Langone Health expands outpatient network in Suffolk County with new locations, specialty services

As part of its mission to enhance access to quality healthcare where people live and work, NYU Langone Health continues to grow its outpatient network in Suffolk County on Long Island with new locations and specialty services.

6 Oct 2022

WTC responders with chronic conditions appear to have severe Covid-19 and long-term sequelae

A study of 1,280 patients treated and monitored at the Stony Brook World Trade Center Health and Wellness Program who also contracted Covid-19 reveals that the responders who have suffered from chronic conditions from WTC exposures and the experience of the 911 tragedy appear to have more infection severity and long-term sequelae than responders who do not have chronic diseases resulting from WTC exposures.

13 Jun 2022

Novel diagnostic platform offers hope for early detection of cancer in patients with Barrett’s esophagus

On a mission to increase early detection of esophageal cancer, University of Colorado (CU) Cancer Center member Sachin Wani, MD, is leading a study to see if a novel diagnostic platform can help endoscopists better identify the disease in patients with a condition called Barrett's esophagus.

8 Feb 2022

Are our bowel habits written in our DNA?

In this interview, News-Medical talks to Dr. Mauro D’Amato about how there could be clues about the regularity of bowel movements within our genes.

24 Dec 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

Weight loss drug Wegovy approved by FDA

The U.S. Food and Drug Administration (FDA) has approved Wegovy (semaglutide) injection (2.4 mg once weekly) as a chronic weight management treatment in obese or overweight adults with a weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), when used along with calorie restriction and physical activity. Wegovy, is a more potent version of Novo Nordisk's diabetes drug semaglutide.

4 Jun 2021

New technique may result in earlier and easier identification of patients with Barrett's esophagus

A new technique for sampling and testing cells from Barrett's esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according to a collaborative study by investigators at Case Western Reserve University and Johns Hopkins Kimmel Cancer Center (JHKCC).

23 Mar 2021

Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers

Results from a large prospective study indicate that gastroesophageal reflux disease (GERD), which also causes heartburn symptoms, is linked with higher risks of various cancers of the larynx (or voice box) and esophagus.

22 Feb 2021

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

A group of three gene variants, commonly inherited together, may provide clues to more successful treatment of pediatric eosinophilic esophagitis (EoE), a chronic inflammation of the food pipe often confused with gastroesophageal reflux disease (GERD).

16 Oct 2020

Researchers highlight when antireflux surgery is needed to treat GERD after endoscopy

Researchers report a growing awareness of gastroesophageal reflux problems among patients who undergo endoscopic, nonsurgical treatment for esophageal achalasia, frequently requiring future surgical intervention.

8 Apr 2020

Chronic cough could be eased with new drug

A pair of studies have shown that chronic cough and its distressing symptoms could be eased with the help of a new drug. Also, the drug does not have side effects that can restrict its use, explain the researchers. The results of the two studies are published in The Lancet Respiratory Medicine, and the European Respiratory Journal, respectively.

26 Feb 2020

$Investigational drug reduces heartburn severity in patients with refractory GERD$

Investigational drug reduces heartburn severity in patients with refractory GERD

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.