Gastroesophageal Reflux Disease News and Research

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Gastroesophageal reflux disease (GERD) is a more serious form of gastroesophageal reflux (GER), which is common. GER occurs when the lower esophageal sphincter (LES) opens spontaneously, for varying periods of time, or does not close properly and stomach contents rise up into the esophagus. GER is also called acid reflux or acid regurgitation, because digestive juices—called acids—rise up with the food. The esophagus is the tube that carries food from the mouth to the stomach. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach.

SpectraScience files new patent application

SpectraScience has announced that it has filed for a new patent with the United States Patent and Trademark Office.

13 Nov 2006

Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma

The results of this study appear in the August 2006 issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS).

2 Aug 2006

Innovative approach for creating a cytomegalovirus vaccine

Each year, about 40,000 children are born infected with human cytomegalovirus, or CMV, and about 8,000 of these children suffer permanent disabilities due to the virus - almost one an hour.

2 Aug 2006

New wireless reflux disease technology more comfortable, not more effective

A wireless device that measures the acidity of stomach contents backwashed into the esophagus allows patients to avoid some of the nose pain and throat discomfort associated with the conventional wired monitor used to manage hard-to-treat gastroesophageal reflux disease.

10 Jul 2006

Lifestyle changes can affect heartburn symptoms

Patients have been known to hug Lauren Gerson, MD, so overjoyed are they at hearing her words. What does she say to them? Go ahead and eat chocolate.

28 Jun 2006

Just a few extra pounds increases women's risk of reflux

According to new research women who gain even a few extra pounds are increasing their risk of getting acid reflux.

4 Jun 2006

Photodynamic therapy may become the first line of treatment for Barrett's esophagus

When you think of heartburn, you probably think of greasy food, not cancer. You may not know that chronic heartburn is linked to esophageal cancer.

7 Apr 2006

Rapamycin (sirolimus) may be effective in treating kidney disease

A widely available drug may be effective in treating kidney disease, report scientists at the University of California, Santa Barbara. They describe the discovery in the online edition of the Proceedings of the National Academies of Science.

21 Mar 2006

Eosinophilic esophagitis gene discovery

Researchers at Cincinnati Children's Hospital Medical Center have discovered the first gene associated with eosinophilic esophagitis, one of a number of eosinophil-related diseases in which the body produces abnormally large amounts of white blood cells that can lead to allergy related illnesses.

7 Feb 2006

Non-steroidal anti-inflammatory drugs may prevent the development of oesophageal adenocarcinoma in patients with Barrett's oesophagus

Barrett’s oesophagus is a metaplastic disorder that develops in about 10% of people with chronic gastro-oesophageal reflux disease. Every year about 0.5%-1% of patients with Barrett’s oesophagus develop oesophageal adenocarcinoma.

10 Nov 2005

Genetic link to dyslexia

About five million Germans have serious learning difficulties when it comes to reading and writing. It is frequently the case that several members of the same family are affected. So hereditary disposition seems to play an important role in the occurrence of dyslexia.

7 Nov 2005

Neurological and neuromuscular diseases raise risk of complications from flu

As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza.

3 Nov 2005

Silent reflux may be the cause of sleep disturbances in patients with unexplained sleep disorders

Patients with sleep complaints but no heartburn symptoms suffered episodes of nighttime acid reflux according to research presented at the 70th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2005

Strong association between physical and mental health problems and restless legs syndrome

Adults with restless legs syndrome (RLS), a common debilitating condition, may be affected physically, mentally, and socially by their disease.

1 Nov 2005

FDA warns against acid-reflux treatment Enteryx

Doctors in the United States have been instructed by the U.S. Food and Drug Administration to stop using Enteryx, a device used to treat acid-reflux disease.

19 Oct 2005

Less invasive surgery effective in treatment of reflux disease

Laparoscopic (minimally invasive) surgery to treat severe reflux disease was effective in relieving symptoms and was associated with high rates of patient satisfaction five years after the procedure, according to a study in the October issue of Archives of Surgery.

17 Oct 2005

Potential beneficial effect of copper orotate

As one of the services for patients with Alzheimer's disease, the Department of Psychiatry at the Saarland University Medical Center offers participation in a clinical phase II trial. This clinical trial aims to elucidate a potential beneficial effect of copper orotate (an organic copper salt), which is given together with a standard cholinesterase inhibitor.

3 Oct 2005

Flavanols help smokers repair blood vessel function

Phytochemicals known as flavanols, which are found in chocolate, fruits and vegetables, can boost the levels of nitric oxide in the blood of smokers and reverse some of their smoking-related impairment in blood vessel function, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005

Treating nighttime heartburn improves sleep and boosts quality of life

The first major multi-center, randomized, double-blind, placebo-controlled trial addressing therapy for gastroesophageal reflux disease (GERD) related sleep disorders is published in the September issue of The American Journal of Gastroenterology.

1 Sep 2005

Gastroesophageal reflux disease (GERD) may be associated with more cases of cancers than previously thought

The relationship of GERD and adenocarcinoma (type of cancer) of the esophagus is clear for tumors located along the tubular portion of the esophagus, regardless of whether Barrett mucosa (a condition where the cellular lining of the esophagus has been changed, often caused by gastric reflux) is found.

20 Jun 2005