Gastrointestinal Tract News and Research

RSS

Mini-gut model provides clues to enterovirus infections in infants

Using immature stem cells to create a miniature model of the gut in the laboratory, researchers at Washington University School of Medicine in St. Louis and the University of Pittsburgh have determined how infection-causing enteroviruses enter the intestine.

31 Jan 2017

New project aims to improve efficiency of cytostatic drugs used in cancer treatment

Wilfried Weber, Professor of Synthetic Biology at the University of Freiburg, has received a grant of roughly €150,000 for his project "Hide and Seek with Cancer Drugs" in which he is working to improve the drugs used in cancer treatment

25 Jan 2017

Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria¬—a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Jan 2017

U of I scientists discuss piglet model used for pediatric nutrition and neurodevelopment research

Pediatric nutrition research has sh own the important effects of early-life nutrition on a baby's development--especially the gastrointestinal tract--and more recent research indicates that nutrition may also have an influence on an infant's brain as it develops.

19 Jan 2017

Protein involved in neurological disorders can travel from brain to stomach

Researchers of the German Center for Neurodegenerative Diseases have found that "alpha-synuclein", a protein involved in a series of neurological disorders including Parkinson's disease, is capable of travelling from brain to stomach and that it does so following a specific pathway.

5 Jan 2017

Scientists use pluripotent stem cells to generate human stomach tissues in laboratory

Scientists report in Nature using pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes.

5 Jan 2017

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers have developed the first sensor capable of objectively identifying inflammatory bowel disease (IBD) and distinguishing between its two subtypes.

4 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

Researchers working to develop pill for inherited bleeding disorders

Motivated by the tribulations of hemophilia patients and their families, researchers funded by the National Institute of Biomedical Imaging and Bioengineering are working to develop a pill to treat this serious inherited bleeding disorder.

23 Dec 2016

Leading journal publishes article about ciliate lipases as therapeutic candidates for oral treatment of EPI

Cilian AG, a biopharmaceutical company focused on the development of subunit vaccines, enzymes and monoclonal antibodies, announces that the European Journal of Gastroenterology & Hepatology, the international, peer-reviewed, online publication journal, has published an article entitled: Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency.

20 Dec 2016

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Defects in the body's regulatory T cells (T reg cells) cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers from The University of Texas Health Science Center at Houston have discovered.

19 Dec 2016

Researchers reveal key role of bacteria-binding protein in intestine

Deficiency in a certain protein in the gastrointestinal tract has been shown to lead to both inflammation and abdominal fat accumulation in mice.

8 Dec 2016

Type 2 diabetes drug may someday help combat breast and ovarian cancers

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.

30 Nov 2016

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol.

29 Nov 2016

UT Austin researchers develop new oral capsule for treating hemophilia patients

In the near future, hemophiliacs could be able to treat their disease by simply swallowing a capsule.

29 Nov 2016

Clinically-proven pharmacy product effective against causes of Traveller's Diarrhoea

It is not only overseas holidays that can be ruined by the dreaded Traveller's Diarrhoea.

23 Nov 2016

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease.

17 Nov 2016

Intestinal parasite increases susceptibility to colitis, study finds

Researchers from the University of Toronto have discovered that mice infected with the common gut parasite Tritrichomonas muris are at an increased risk of developing inflammatory colitis.

11 Nov 2016

Researchers develop new strategy to immunize against microbes that cause foodborne illness

University of California, Irvine and MIT researchers have developed a new strategy to immunize against microbes that invade the gastrointestinal tract, including Salmonella, which causes more foodborne illness in the United States than any other bacteria.

8 Nov 2016

New biological mechanism generates cells to fight against Candida albicans infections, find researchers

Researchers from the Universitat de València and the Cedar Sinai Medical Center in Los Angeles have partnered to describe a biological mechanism that generates cells which are better equipped to fight off serious infections caused by the Candida albicansfungus.

26 Oct 2016