Gastrointestinal Tract News and Research

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Outlook for Crohn's disease improves due to new therapies

A study led by Mayo Clinic has found that infliximab (Remicade) administered alone (monotherapy) or in combination with azathioprine is a more effective treatment for patients with moderate to severe Crohn's disease than azathioprine alone.

6 Oct 2008

New drug hope for cystic fibrosis patients

A science conference in the UK has heard some good news which offers hope to cystic fibrosis (CF) patients worldwide.

10 Sep 2008

Alte Biosciences files patent for novel inflammatory bowel disease drugs

Alte Bioscience, Inc., a development stage pharmaceutical company, is pleased to announce the filing of a provisional patent for a new class of drugs that may benefit patients with inflammatory bowel disease.

3 Sep 2008

New genetic link to inflammatory bowel diseases discovered

A study which entailed scientists trawling through the genetic code of thousands of people, has revealed two new genes involved in childhood inflammatory bowel disease, a painful condition that includes Crohn's disease and ulcerative colitis (UC).

1 Sep 2008

Discovery of new genes for inflammatory bowel disease in children

Researchers have discovered two new genes that increase the risk of developing inflammatory bowel disease (IBD) in childhood.

31 Aug 2008

Scientists engineer first drug-delivery particles capable of passing through human mucus

Chemical engineers from Johns Hopkins University have broken the "mucus barrier," engineering the first drug-delivery particles capable of passing through human mucus - regarded by many as nearly impenetrable - and carrying medication that could treat a range of diseases. Those conditions include lung cancer, cervical cancer and cystic fibrosis, the research noted in a presentation scheduled for the 236th National Meeting of the American Chemical Society.

20 Aug 2008

Study first to show range and severity of birth defects associated with Type 1 and Type 2 diabetes

Women who receive a diagnosis of diabetes before they become pregnant are three to four times more likely to have a child with one or even multiple birth defects than a mother who receives a diagnosis of diabetes while pregnant or a mother who is not diabetic, according to a study by the Centers for Disease Control and Prevention (CDC), released in the American Journal of Obstetrics and Gynecology

29 Jul 2008

Potential new way to prevent graft-versus-host disease

A new University of Michigan study in mice suggests that a drug recently approved to fight cancer tumors is also able to reduce the effects of graft-versus-host disease, a common and sometimes fatal complication for people who have had bone marrow transplants.

10 Jul 2008

Genetic link between Crohn's and asthma discovered

Research into the genetic causes of Crohn's disease has revealed that the gene ORMDL3, known to be a risk factor for childhood asthma, is also associated with Crohn's disease, and in the process links between the condition and other diseases have been found.

2 Jul 2008

Hunger hormone ghrelin increases during stress, may have antidepressant effect

New research at UT Southwestern Medical Center may explain why some people who are stressed or depressed overeat.

24 Jun 2008

Nitrates in vegetables protect against gastric ulcers

Vegetables that are rich in nitrates protect the stomach from damage. This takes place through conversion of nitrates into nitrites by the bacteria in the oral cavity and subsequent transformation into biologically active nitric oxide in the stomach. The Swedish researcher Joel Petersson has described the process, which also means that antibacterial mouthwashes can be harmful for the stomach.

7 May 2008

Allergy expert says expect cure for peanut allergy in five years

The announcement by an American expert that within the next five years some form of immunotherapy will be available to treat peanut allergy, will bring relief to many concerned parents.

5 May 2008

Hepatitis C therapy peginterferon alfa-2b shows promise

The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented today at the 43rd annual meeting of the European Association for the Study of the Liver (EASL).

24 Apr 2008

Potential link found between bacteria found in the human digestive system and obesity

Obesity is more than a cosmetic concern because it increases a person's risk for developing high blood pressure, diabetes and many other serious health problems.

2 Apr 2008

The effect of melatonin on colitis

In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration.

19 Mar 2008

New imaging technique provides better view of Barrett's esophagus

Novel techniques to improve the quality of imaging are helping doctors get a better look at esophageal conditions such as Barrett's esophagus (BE), but they do not necessarily improve the diagnosis or physician agreement on images, according to a study published this month in Gastroenterology , the official journal of the American Gastroenterological Association (AGA) Institute.

12 Mar 2008

Nasal polyps from analgesics

If a patient develops respiratory problems after taking analgesics, this indicates that the active substances are poorly tolerated.

11 Mar 2008

Research in diabetes surgery suggests origins of disease

Growing evidence shows that surgery may effectively cure Type 2 diabetes -- an approach that not only may change the way the disease is treated, but that introduces a new way of thinking about diabetes.

5 Mar 2008

Risks of CVD for COX-2 inhibitors lower than previously reported

In an article published in the March issue of the Journal of Cardiovascular Pharmacology and Therapeutics, researchers from Florida Atlantic University (FAU) assess the totality of evidence, including strengths and limitations of different types of evidence contributing to the debate about cardiovascular disease (CVD) risks of cyclooxygenase-2 (COX-2) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).

27 Feb 2008

Endoscopic ultrasound-guided therapy safe for severe gastrointestinal bleeding patients

A new Mayo Clinic study found that endoscopic ultrasound-guided therapy appears to be a safe and effective treatment for patients with severe gastrointestinal bleeding for whom conventional therapies have failed.

21 Feb 2008