Gene Silencing News and Research

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Study describes vulnerability shared by large subset of cancer cell lines

Study describes vulnerability shared by large subset of cancer cell lines

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Novel DNA nanoplatform delivers anticancer agents to multidrug-resistant tumors

Novel DNA nanoplatform delivers anticancer agents to multidrug-resistant tumors

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

New study focuses on two-way gene switches controlling gene activity

New study focuses on two-way gene switches controlling gene activity

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Penn researchers find common thread linking almost all TNR expansion diseases

Penn researchers find common thread linking almost all TNR expansion diseases

Arrowhead completes dosing of ARO-AAT Phase 1 study to treat rare genetic liver disease

Arrowhead completes dosing of ARO-AAT Phase 1 study to treat rare genetic liver disease

EC grants marketing authorization for ONPATTRO (patisiran) in Europe

EC grants marketing authorization for ONPATTRO (patisiran) in Europe

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Newer version of ALS drug may effectively treat inherited form of the disease

Newer version of ALS drug may effectively treat inherited form of the disease

Researchers employ nucleotide-based gene silencing to mitigate common ataxia

Researchers employ nucleotide-based gene silencing to mitigate common ataxia

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients