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Researchers design new tool for identifying protein function from genetic code

Mayo Clinic researchers have designed a new tool for identifying protein function from genetic code. A team led by Stephen Ekker, Ph.D., succeeded in switching individual genes off and on in zebrafish, then observing embryonic and juvenile development.

10 May 2011

Scientists decipher genome of tropical marine organism

An international team of researchers led by scientists at Scripps Institution of Oceanography at UC San Diego has deciphered the genome of a tropical marine organism known to produce substances potentially useful against human diseases.

10 May 2011

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Three UCSF scientists have received grants from the California Institute for Regenerative Medicine to advance their investigations of treatment strategies for degenerative muscle diseases, such as muscular dystrophy, and heart disease, and to determine why human embryonic stem cells are susceptible to forming tumors.

10 May 2011

Genetic mutation linked to Kufs disease

According to a new study, a genetic mutation thought to be responsible for the rare hereditary brain disorder Kufs disease is finally identified. The research was carried out by Dr Melanie Bahlo and her team at the Walter and Eliza Hall Institute's bioinformatics department in Parkville, Australia, in partnership with neurologist and epilepsy specialists Professor Sam Berkovic and Dr Todor Arsov from the University of Melbourne, Australia.

10 May 2011

Three Ontario projects set to further knowledge and discovery in biomonitoring, drug development

As part of the Genome Canada Large-Scale Applied Research Project Competition, which as a whole awarded over $58 million to 16 projects across the country, the researchers in Ontario will be focusing on biomonitoring, understanding gene function with the aim of identifying genes or proteins for drug targets, and the creation of synthetic antibodies to target cancers and other diseases.

9 May 2011

Intrexon to deploy Novici's GRAMMR technology in concert with UltraVector platform

Intrexon Corporation, a next generation synthetic biology company, today announced an agreement with Novici Biotech LLC in which Intrexon has licensed certain non-exclusive rights to the use of Novici's patented GRAMMR® technology for high-resolution genetic reassortment ("gene shuffling").

9 May 2011

FDA clears Affymetrix's new gene profiling reagents for use in microarray instrument system

Affymetrix, Inc. today announced that the U.S. Food and Drug Administration has cleared the addition of new gene expression reagents as accessories to its GeneChip Microarray Instrument System for in vitro diagnostic use, making Affymetrix the first in the industry to provide a comprehensive microarray-based clinical toolkit for diagnostic test development, signature discovery for companion diagnostics, and translational initiatives. Affymetrix Gene Profiling Reagents offer unparalleled convenience by simplifying assay workflow, decreasing hands-on time, and reducing quality control testing compared to research-use-only-produced products.

9 May 2011

New international project to create more mutant genes, address shortage of Cre resources

Local scientists are now part of an International team compiling an enormous bank of resources for research into the functions of all known genes. The development of these biological resources will eventually allow scientists to know how the human genome behaves in health and disease.

9 May 2011

Researchers analyze gene expression profiles to understand molecular mechanisms behind various diseases

Over the past decades, researchers seeking to understand molecular mechanisms underlying various diseases, notably cancer, have taken advantage of DNA microarrays to interrogate tissues specimen of patients for the expression status of thousands of genes at once.

9 May 2011

Breast cancer linked to lifestyle & three new genes

According to the latest research as many as 20,000 British women could avoid developing breast cancer if they took more exercise, drank less and ate better. The World Cancer Research Fund recommends taking half an hour of physical exercise a day, limiting alcohol consumption to just one drink daily and losing weight.

8 May 2011

Scientists to identify host bacteria that colonize different hybrids

Literature tells us that "no man is an island entire unto itself," but science reveals that we are in fact a walking, talking colony of microscopic creatures.

7 May 2011

Breast cancer cells utilize tissue stem cell EMT for tumor metastasis

Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer.

7 May 2011

Researchers find temperature-sensing protein in immune cells

Researchers at The Scripps Research Institute have found a temperature-sensing protein within immune cells that, when tripped, allows calcium to pour in and activate an immune response.

7 May 2011

Spotlight on the NDM-1 “superbug” highlights the long-standing but increasingly alarming situation of antibiotic resistance globally

At the world’s largest conference on infectious diseases – the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) which opens today – a special Symposium on NMD-1 (New Delhi metallo-beta-lactamase) will focus on the implications of the increasing detection of this gene, which makes bacteria highly resistant to almost all known antibiotics. This is part of an alarming trend of antibiotic resistance that threatens to turn back the clock on years of progress following the discovery of antimicrobials, which revolutionised human health globally.

6 May 2011

Study offers means of activating T cells to fight disease without antigenic triggers

For much of the time our T cells-the white blood cells that act as the police of the immune system-are in what immunologists call a "quiescent state," a sort of standby mode. For years, scientists have wondered if quiescence occurred by default or whether T cells need to work at remaining silent.

6 May 2011

UT Southwestern researcher measures estrogen's effect on breast cancer cells

A UT Southwestern Medical Center researcher has identified the most comprehensive measurement to date of estrogen's effect on breast cancer cells, showing for the first time how immediate and extensive the effect is.

6 May 2011

Scientists use new technologies to identify genetic cause of Kufs disease

Scientists from the Walter and Eliza Hall Institute and the University of Melbourne have used innovative new technologies to identify the gene responsible for a rare but fatal hereditary brain disorder. The discovery will make it possible to diagnose the disease through a blood test rather than a brain biopsy.

6 May 2011

Researchers identify unexpected triple-negative breast cancer marker

German researchers have identified an unexpected molecular marker that predicts how sensitive hard-to-treat triple-negative breast cancers are to chemotherapy.

5 May 2011

Two breast cancer genomic tests produce broadly similar results for high and low-risk patients

Two multi-gene tests designed to predict the risk of disease progression and response to chemotherapy in breast cancer produce broadly similar results for high- and low-risk patients, but do not always agree in their predictions for those at intermediate risk, a new analysis shows.

5 May 2011

Genome epigenetic analysis reveals new ways to detect and treat breast cancer

The most comprehensive analysis yet of the epigenetic modifications present in breast cancer has revealed potentially important new ways to detect and treat the disease, Belgian researchers have reported.

5 May 2011

Genes News and Research

Researchers design new tool for identifying protein function from genetic code

Scientists decipher genome of tropical marine organism

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Genetic mutation linked to Kufs disease

Three Ontario projects set to further knowledge and discovery in biomonitoring, drug development

Intrexon to deploy Novici's GRAMMR technology in concert with UltraVector platform

FDA clears Affymetrix's new gene profiling reagents for use in microarray instrument system

New international project to create more mutant genes, address shortage of Cre resources

Researchers analyze gene expression profiles to understand molecular mechanisms behind various diseases

Breast cancer linked to lifestyle & three new genes

Scientists to identify host bacteria that colonize different hybrids

Breast cancer cells utilize tissue stem cell EMT for tumor metastasis

Researchers find temperature-sensing protein in immune cells

Spotlight on the NDM-1 “superbug” highlights the long-standing but increasingly alarming situation of antibiotic resistance globally

Study offers means of activating T cells to fight disease without antigenic triggers

UT Southwestern researcher measures estrogen's effect on breast cancer cells

Scientists use new technologies to identify genetic cause of Kufs disease

Researchers identify unexpected triple-negative breast cancer marker

Two breast cancer genomic tests produce broadly similar results for high and low-risk patients

Genome epigenetic analysis reveals new ways to detect and treat breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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