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Iverson Genetic Diagnostics receives CMS approval for Warfarin clinical study

Iverson Genetic Diagnostics today announced the company has received approval from CMS to conduct a WARFARIN Clinical Study. The two-year (2) study will assess the impact of genetic information in calculating doses and the changes in the rate of adverse events when initiating Warfarin drug therapy. These changes will be compared against doses initiated without genetic data. The randomized and blinded, multi-center study will involve more than 7000 participants at over 50 sites nationwide.

27 Jul 2010

Affymetrix releases new data for rapid design of custom arrays

Affymetrix, Inc.today announced that it has released an unparalleled data set based on extensive validation of novel SNPs from the 1000 Genomes Project. This data will give researchers access to more rare mutations for genome-wide association studies and will enable the rapid design of custom arrays for a variety of applications, including the validation of sequencing results.

27 Jul 2010

HTG patients face increased risk for heart disease, stroke: Study

It can make blood look like cream of tomato soup. Patients with high levels of triglycerides in their blood, a disease called hypertriglyceridemia face an increased risk for heart disease and stroke. HTG affects one in 20 people in North America and is also associated with obesity, diabetes and pancreatitis. Most people now understand the importance of LDL, the bad cholesterol and HDL, the good cholesterol, to their overall health.

26 Jul 2010

Control of cell migration gene can reduce spread of oral cancer cells: Study

The spread of cancer cells in the tongue may be reduced if a gene that regulates cancer cell migration can be controlled, according to new research at the University of Illinois at Chicago.

26 Jul 2010

Research on new treatments for FXS to be presented at International Fragile X Conference

Accelerated research findings leading to potentially significant new treatments for fragile X syndrome will be presented to nearly 1,000 family members and professionals at the 12th International Fragile X Conference in Dearborn July 21-25.

23 Jul 2010

IBS associated with structural changes in specific brain regions

A large academic study has demonstrated structural changes in specific brain regions in female patients with irritable bowel syndrome, a condition that causes pain and discomfort in the abdomen, along with diarrhea, constipation or both

23 Jul 2010

National Jewish Health receives $31M NIH contract to study skin infections associated with atopic dermatitis

The National Institute of Allergy and Infections Disease has awarded a five-year $31 million contract to National Jewish Health, which is leading a consortium of academic medical centers seeking to better understand skin infections associated with atopic dermatitis. The researchers will focus on antibiotic-resistant staphylococcus aureus (MRSA) infections and widespread viral infections of the skin, both of which are more prevalent among atopic dermatitis patients.

23 Jul 2010

Gene expression profiling may provide molecular diagnostic tool to diagnose depression

Blood tests have been extremely important tools aiding doctors in making medical diagnoses and in guiding the treatment of many diseases. However, psychiatry is one area of medicine where there are few diagnostic blood tests.New scientific fields may someday generate blood tests that can be used for these purposes. Some of the areas under increasingly intensive study are genetics, the study of variations in the genes that can be extracted from blood cells, and genomics like proteomics, the measurement of the levels of specific proteins in the blood, and gene expression profiling, which measures the levels of RNA produced from DNA as an indication of the level of the "activity" of particular genes.

23 Jul 2010

New understanding on insulin resistance, action of diabetes drugs may lead to safer medication

A new understanding of insulin resistance and the action of diabetes drugs such as Avandia and Actos could pave the way for improved medications that are more selective and safer, say scientists from Dana-Farber Cancer Institute and The Scripps Research Institute.Our findings strongly suggest that good and bad effects of these drugs can be separated by designing second-generation drugs that focus on the newly uncovered mechanism, said Bruce Spiegelman, PhD, of Dana-Farber, senior author on a report appearing in the July 22 issue of Nature.

22 Jul 2010

Genomics researchers study role of protein in metabolic disorders, heart disease

Studying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments.

22 Jul 2010

Scientists uncover new mechanism that reduces risk of type 2 diabetes, cardiovascular disease

In a joint study, scientists from The Scripps Research Institute and the Dana-Farber Cancer Institute at Harvard University have uncovered a novel mechanism that dramatically increases insulin sensitivity and reduces the risk of developing type 2 diabetes and cardiovascular disease.

22 Jul 2010

Affymetrix launches QuantiGene ViewRNA Assay formats

Affymetrix, Inc. today announced the launch of QuantiGene® ViewRNA Assay formats, which enable a new era of "in situ multiplex gene expression analysis" by allowing drug screening of native cells and advancing the pace of biomarker disease research and stem cell studies. These in situ assays enable researchers to visualize gene expression in individual cells at an unprecedented level of sensitivity and speed.

22 Jul 2010

TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers

22 Jul 2010

New research identifies stem cells that generate three critical classes of nerve cells

New research, published in the journal Development, by Dr. Anthony-Samuel LaMantia, professor of Pharmacology & Physiology and director of the newly formed GW Institute for Neuroscience, and his colleagues have identified the stem cells that generate three critical classes of nerve cells - olfactory receptors, vomeronasal and gonadotropin releasing hormone neurons - that are responsible for enabling animals and humans, to eat, interact socially and reproduce.

22 Jul 2010

Study links application of disinfectants in recreational pools to adverse health outcomes

Splashing around in a swimming pool on a hot summer day may not be as safe as you think. A recent University of Illinois study links the application of disinfectants in recreational pools to previously published adverse health outcomes such as asthma and bladder cancer.

22 Jul 2010

Valproic acid halts vision loss in patients with retinitis pigmentosa

Researchers at the University of Massachusetts Medical School believe they may have found a new treatment for retinitis pigmentosa, a severe neurodegenerative disease of the retina that ultimately results in blindness. One of the more common retinal degenerative diseases, RP is caused by the death of photoreceptor cells and affects 1 in 4,000 people in the United States. RP typically manifests in young adulthood as night blindness or a loss of peripheral vision and in many cases progresses to legal blindness by age 40.

22 Jul 2010

Buffer among metbolism pathways induces cancer suppressing gene mutation: Research

Eighty years ago, the medical establishment believed cancer was caused by a dysfunction of metabolism, but the idea went out of vogue. Now, scientists are again looking at metabolism and its role in cancer and other common diseases. Metabolism is a highly connected network of reactions that are arranged in parallel and interacting pathways. Such parallelism can mask how genes are linked with disease traits and make it difficult to treat conditions.

22 Jul 2010

Roche, Exiqon join marketing forces for RealTime ready assays, microRNA PCR systems

Roche and Exiqon join marketing forces for Roche Applied Science's RealTime ready assays and Exiqon`s miRCURY LNA Universal RT microRNA qPCR system. As indicated by respective links on their websites, each system will complement the cooperator's product portfolio.

21 Jul 2010

INRA Genomic Platform core facility now provides services on Fluidigm's BioMark System for Genetic Analysis

Fluidigm Corporation today announced that the Toulouse Midi-Pyrénées Genomic Platform - Genotoul INRA core facility is now providing a wide range of services on a BioMark™ System for Genetic Analysis to a wide range of French researchers. These services include SNP genotyping, gene expression analysis and digital PCR quantification of DNA libraries for next-generation sequencing. The INRA has been validating the performance of the system on several projects over the past year.

21 Jul 2010

University of Luebeck becomes part of Metaminer Cardiac Partnership

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that Dr. Salah Mohamed in Department of Cardio and Thoracic Vascular Surgery at the University of Luebeck and his team will be part of the Metaminer Cardiac Partnership. Dr. Mohamed is published within 6 different reputed Scientific American Journals in connection with Biomarker Discovery work performed for the American Heart Association.

21 Jul 2010

Genes News and Research

Iverson Genetic Diagnostics receives CMS approval for Warfarin clinical study

Affymetrix releases new data for rapid design of custom arrays

HTG patients face increased risk for heart disease, stroke: Study

Control of cell migration gene can reduce spread of oral cancer cells: Study

Research on new treatments for FXS to be presented at International Fragile X Conference

IBS associated with structural changes in specific brain regions

National Jewish Health receives $31M NIH contract to study skin infections associated with atopic dermatitis

Gene expression profiling may provide molecular diagnostic tool to diagnose depression

New understanding on insulin resistance, action of diabetes drugs may lead to safer medication

Genomics researchers study role of protein in metabolic disorders, heart disease

Scientists uncover new mechanism that reduces risk of type 2 diabetes, cardiovascular disease

Affymetrix launches QuantiGene ViewRNA Assay formats

TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers

New research identifies stem cells that generate three critical classes of nerve cells

Study links application of disinfectants in recreational pools to adverse health outcomes

Valproic acid halts vision loss in patients with retinitis pigmentosa

Buffer among metbolism pathways induces cancer suppressing gene mutation: Research

Roche, Exiqon join marketing forces for RealTime ready assays, microRNA PCR systems

INRA Genomic Platform core facility now provides services on Fluidigm's BioMark System for Genetic Analysis

University of Luebeck becomes part of Metaminer Cardiac Partnership

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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